Exopeptidase inhibitor (original) (raw)
An exopeptidase inhibitor is a drug that inhibits one or more exopeptidase enzymes. Exopeptidases are one of two types of proteases (enzymes that break down proteins and peptides), the other being endopeptidases. Exopeptidases cleave peptide bonds of terminal amino acids, resulting in the release of a single amino acid or dipeptide from the peptide chain, whereas endoeptidases break non-terminal bonds (that is, they cut proteins/peptides into two chains).
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| dbo:abstract | An exopeptidase inhibitor is a drug that inhibits one or more exopeptidase enzymes. Exopeptidases are one of two types of proteases (enzymes that break down proteins and peptides), the other being endopeptidases. Exopeptidases cleave peptide bonds of terminal amino acids, resulting in the release of a single amino acid or dipeptide from the peptide chain, whereas endoeptidases break non-terminal bonds (that is, they cut proteins/peptides into two chains). Some examples of exopeptidase inhibitors include amastatin, bestatin (ubenimex), puromycin, 1,10-phenanthroline, D-phenylalanine, ACE inhibitors, DPP-4 inhibitors, and exogenous MMP inhibitors like batimastat and marimastat. Various enkephalinase inhibitors, such as ketalorphan, spinorphin, and tynorphin, are mainly exopeptidase inhibitors. (en) |
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| dbo:wikiPageRevisionID | 1073190216 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Puromycin dbr:Endopeptidase dbr:Endopeptidase_inhibitor dbr:Enkephalinase_inhibitor dbr:Enzyme_inhibitor dbr:Peptide dbr:Enzyme dbr:Batimastat dbr:Matrix_metalloproteinase_inhibitor dbr:Drug dbr:ACE_inhibitor dbr:Amino_acid dbc:Protease_inhibitors dbr:Amastatin dbr:Dipeptide dbr:Protease dbr:Protein dbr:Marimastat dbr:Spinorphin dbr:Exogenous dbr:D-phenylalanine dbr:Exopeptidase dbr:Peptide_bond dbr:Tynorphin dbr:Ketalorphan dbr:DPP-4_inhibitor dbr:1,10-phenanthroline dbr:Bestatin |
| dbp:wikiPageUsesTemplate | dbt:More_citations_needed dbt:Pharmacology-stub dbt:Reflist |
| dct:subject | dbc:Protease_inhibitors |
| gold:hypernym | dbr:Drug |
| rdf:type | dbo:Drug |
| rdfs:comment | An exopeptidase inhibitor is a drug that inhibits one or more exopeptidase enzymes. Exopeptidases are one of two types of proteases (enzymes that break down proteins and peptides), the other being endopeptidases. Exopeptidases cleave peptide bonds of terminal amino acids, resulting in the release of a single amino acid or dipeptide from the peptide chain, whereas endoeptidases break non-terminal bonds (that is, they cut proteins/peptides into two chains). (en) |
| rdfs:label | Exopeptidase inhibitor (en) |
| owl:sameAs | yago-res:Exopeptidase inhibitor wikidata:Exopeptidase inhibitor https://global.dbpedia.org/id/2MfsW |
| prov:wasDerivedFrom | wikipedia-en:Exopeptidase_inhibitor?oldid=1073190216&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Exopeptidase_inhibitor |
| is dbo:wikiPageWikiLink of | dbr:Endopeptidase_inhibitor |
| is foaf:primaryTopic of | wikipedia-en:Exopeptidase_inhibitor |