F-ATPase (original) (raw)
F-ATPase, also known as F-Type ATPase, is an ATPase/synthase found in bacterial plasma membranes, in mitochondrial inner membranes (in oxidative phosphorylation, where it is known as Complex V), and in chloroplast thylakoid membranes. It uses a proton gradient to drive ATP synthesis by allowing the passive flux of protons across the membrane down their electrochemical gradient and using the energy released by the transport reaction to release newly formed ATP from the active site of F-ATPase. Together with V-ATPases and A-ATPases, F-ATPases belong to superfamily of related rotary ATPases.
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| dbo:abstract | F-ATPase, also known as F-Type ATPase, is an ATPase/synthase found in bacterial plasma membranes, in mitochondrial inner membranes (in oxidative phosphorylation, where it is known as Complex V), and in chloroplast thylakoid membranes. It uses a proton gradient to drive ATP synthesis by allowing the passive flux of protons across the membrane down their electrochemical gradient and using the energy released by the transport reaction to release newly formed ATP from the active site of F-ATPase. Together with V-ATPases and A-ATPases, F-ATPases belong to superfamily of related rotary ATPases. F-ATPase consists of two domains: * the Fo domain, which is integral in the membrane and is composed of 3 different types of integral proteins classified as a, b and c. * the F1, which is peripheral (on the side of the membrane that the protons are moving into). F1 is composed of 5 polypeptide units α3β3γδε that bind to the surface of the Fo domain. F-ATPases usually work as ATP synthases instead of ATPases in cellular environments. That is to say, it usually makes ATP from the proton gradient instead of working in the other direction like V-ATPases typically do. They do occasionally revert as ATPases in bacteria. (en) F-АТФаза, также известная как АТФаза F-типа, представляет собой АТФазу/синтазу, обнаруженную в бактериальных клеточных мембранах, во внутренних мембранах митохондрий (при окислительном фосфорилировании, где она известна как Комплекс V) и в мембранных тилакоидов хлоропластов. F-АТФаза использует протонный градиент для управления синтезом АТФ, используя энергию, высвобождаемую в результате транспортной реакции, для высвобождения вновь образованного АТФ из активного центра F-АТФазы. Вместе с V-АТФазой и A-АТФазой, F-АТФаза принадлежат к суперсемейству родственных роторных ионтранслирующих АТФаз. F-АТФазы обычно работают как АТФ-синтазы вместо АТФаз в клеточной среде. Другими словами, он обычно производит АТФ из протонного градиента вместо того, чтобы работать в другом направлении, как это обычно делают V-АТФазы. Иногда они превращаются в АТФазы у бактерий. (ru) |
| dbo:symbol | F-ATPase |
| dbo:thumbnail | wiki-commons:Special:FilePath/Atpsynthase.jpg?width=300 |
| dbo:wikiPageID | 2705942 (xsd:integer) |
| dbo:wikiPageLength | 4748 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1082976598 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Proton dbr:Plasma_membrane dbr:Alkalosis dbr:V-ATPase dbr:Inhibitor_protein dbr:Inner_mitochondrial_membrane dbr:Thylakoid dbc:Membrane_proteins dbr:ATP_synthase_delta/OSCP_subunit dbr:Adenosine_triphosphate dbr:Oxidative_phosphorylation dbr:ATP_synthase dbr:ATPase dbr:Acidosis dbr:Chloroplast dbr:Oligomycin dbr:Polypeptides |
| dbp:caption | Simplified model of FOF1-ATPase alias ATP synthase of E. coli. Subunits of the enzyme are labeled accordingly (en) |
| dbp:membranomeSuperfamily | 227 (xsd:integer) |
| dbp:name | F-ATPase (en) |
| dbp:opmFamily | 5 (xsd:integer) |
| dbp:opmProtein | 6 (xsd:integer) |
| dbp:symbol | F-ATPase (en) |
| dbp:tcdb | 3 (xsd:integer) |
| dbp:width | 200 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Reflist dbt:See_also dbt:Short_description dbt:ATPase dbt:Pfam_box |
| dcterms:subject | dbc:Membrane_proteins |
| gold:hypernym | dbr:ATPase |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:WikicatMembraneProteins yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Protein yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 |
| rdfs:comment | F-ATPase, also known as F-Type ATPase, is an ATPase/synthase found in bacterial plasma membranes, in mitochondrial inner membranes (in oxidative phosphorylation, where it is known as Complex V), and in chloroplast thylakoid membranes. It uses a proton gradient to drive ATP synthesis by allowing the passive flux of protons across the membrane down their electrochemical gradient and using the energy released by the transport reaction to release newly formed ATP from the active site of F-ATPase. Together with V-ATPases and A-ATPases, F-ATPases belong to superfamily of related rotary ATPases. (en) F-АТФаза, также известная как АТФаза F-типа, представляет собой АТФазу/синтазу, обнаруженную в бактериальных клеточных мембранах, во внутренних мембранах митохондрий (при окислительном фосфорилировании, где она известна как Комплекс V) и в мембранных тилакоидов хлоропластов. F-АТФаза использует протонный градиент для управления синтезом АТФ, используя энергию, высвобождаемую в результате транспортной реакции, для высвобождения вновь образованного АТФ из активного центра F-АТФазы. Вместе с V-АТФазой и A-АТФазой, F-АТФаза принадлежат к суперсемейству родственных роторных ионтранслирующих АТФаз. (ru) |
| rdfs:label | F-ATPase (en) F-АТФаза (ru) |
| rdfs:seeAlso | dbr:Function dbr:ATP_synthase |
| owl:sameAs | freebase:F-ATPase yago-res:F-ATPase wikidata:F-ATPase dbpedia-ru:F-ATPase https://global.dbpedia.org/id/4jTrT |
| prov:wasDerivedFrom | wikipedia-en:F-ATPase?oldid=1082976598&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Atpsynthase.jpg |
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