Fenamic acid (original) (raw)
Fenamic acid is an organic compound, which, especially in its ester form, is called fenamate. serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid. Fenamic acid can be synthesized from 2-chlorobenzoic acid and can be converted into acridone.
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| dbo:abstract | Fenamic acid is an organic compound, which, especially in its ester form, is called fenamate. serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid. Fenamic acid can be synthesized from 2-chlorobenzoic acid and can be converted into acridone. (en) L'acide fénamique (parfois écrit « acide phénamique ») est un composé aromatique de formule C13H11NO2, dérivé de la diphénylamine et de l'acide anthranilique. Il donne son nom à la famille de ses dérivés utilisés comme anti-inflammatoires non stéroïdiens (AINS) tels que l'acide méfénamique, l', l' ou l'acide méclofénamique, les acides fénamiques (ou acides N-arylanthraniliques). Toutefois, un certain nombre de composés classés dans cette famille pharmacologique ne sont pas stricto sensu des dérivés de l'acide fénamique, comme la par exemple. L'acide fénamique peut être synthétisé à partir de l'acide 2-chlorobenzoïque et peut être converti en acridone. (fr) Ácido fenámico es una molécula que sirve como una estructura de matriz para varios fármacos anti-inflamatorios no esteroideos, incluyendo el ácido mefenámico, ácido tolfenámico, ácido flufenámico, y ácido meclofenámico. Este compuesto se puede sintetizar por la reacción de ácido 2-clorobenzoico y anilina, con base y óxido de cobre catalizador en la reacción de Goldberg. La auto-condensación de ácido fenámico produce acridona. (es) フェナム酸（英: Fenamic acid）とは、芳香族アミノ酸の一つ。N-フェニルアントラニル酸、フェナミン酸ともいう。メフェナム酸、フルフェナム酸、メクロフェナム酸、トルフェナム酸などの非ステロイド性抗炎症薬はフェナム酸からの誘導体であり、フェナム酸系と称される。 2-とアニリンを、酸化銅(II)の存在下でウルマン縮合させて得られる。 フェナム酸が自己縮合すると、アクリドンになる。 (ja) Ácido fenâmico é uma molécula que serve como estrutura base para vários anti-inflamatórios não esteroides, como ácido mefenâmico, , e ácido meclofenâmico. Este composto pode ser sintetizado pela reação do com anilina, usando como catalisador o óxido de cobre na . A auto-condensação do ácido fenâmico gera a . (pt) 芬那酸（Fenamic acid），是一系列非類固醇消炎止痛藥的基本組成分子，衍生的藥物包括甲芬那酸、、及。該化合物可以2-氯苯甲酸與苯胺為基礎，並用氧化銅作為催化劑，透過Goldberg反應而合成。 (zh) |
| dbo:alternativeName | N-phenylanthranilic acid (en) |
| dbo:iupacName | 2-Anilinobenzoic acid (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Fenamic_acid.png?width=300 |
| dbo:wikiPageID | 13591212 (xsd:integer) |
| dbo:wikiPageLength | 2935 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1024222231 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Meclofenamic_acid dbr:Mefenamic_acid dbr:Organic_compound dbr:Anthranilic_acid dbr:2-chlorobenzoic_acid dbr:Tolfenamic_acid dbr:Acridone dbc:Anthranilic_acids dbr:Flufenamic_acid dbr:Nonsteroidal_anti-inflammatory_drug dbc:Nonsteroidal_anti-inflammatory_drugs |
| dbp:imagealt | Ball-and-stick model of fenamic acid (en) |
| dbp:imagefile | Fenamic acid 3D ball.png (en) Fenamic acid.png (en) |
| dbp:imagesize | 200 (xsd:integer) |
| dbp:othernames | N-phenylanthranilic acid (en) |
| dbp:pin | 2 (xsd:integer) |
| dbp:verifiedfields | changed (en) |
| dbp:verifiedrevid | 414204436 (xsd:integer) |
| dbp:watchedfields | changed (en) |
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| dcterms:subject | dbc:Anthranilic_acids dbc:Nonsteroidal_anti-inflammatory_drugs |
| gold:hypernym | dbr:Molecule |
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| rdfs:comment | Fenamic acid is an organic compound, which, especially in its ester form, is called fenamate. serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid. Fenamic acid can be synthesized from 2-chlorobenzoic acid and can be converted into acridone. (en) Ácido fenámico es una molécula que sirve como una estructura de matriz para varios fármacos anti-inflamatorios no esteroideos, incluyendo el ácido mefenámico, ácido tolfenámico, ácido flufenámico, y ácido meclofenámico. Este compuesto se puede sintetizar por la reacción de ácido 2-clorobenzoico y anilina, con base y óxido de cobre catalizador en la reacción de Goldberg. La auto-condensación de ácido fenámico produce acridona. (es) フェナム酸（英: Fenamic acid）とは、芳香族アミノ酸の一つ。N-フェニルアントラニル酸、フェナミン酸ともいう。メフェナム酸、フルフェナム酸、メクロフェナム酸、トルフェナム酸などの非ステロイド性抗炎症薬はフェナム酸からの誘導体であり、フェナム酸系と称される。 2-とアニリンを、酸化銅(II)の存在下でウルマン縮合させて得られる。 フェナム酸が自己縮合すると、アクリドンになる。 (ja) Ácido fenâmico é uma molécula que serve como estrutura base para vários anti-inflamatórios não esteroides, como ácido mefenâmico, , e ácido meclofenâmico. Este composto pode ser sintetizado pela reação do com anilina, usando como catalisador o óxido de cobre na . A auto-condensação do ácido fenâmico gera a . (pt) 芬那酸（Fenamic acid），是一系列非類固醇消炎止痛藥的基本組成分子，衍生的藥物包括甲芬那酸、、及。該化合物可以2-氯苯甲酸與苯胺為基礎，並用氧化銅作為催化劑，透過Goldberg反應而合成。 (zh) L'acide fénamique (parfois écrit « acide phénamique ») est un composé aromatique de formule C13H11NO2, dérivé de la diphénylamine et de l'acide anthranilique. Il donne son nom à la famille de ses dérivés utilisés comme anti-inflammatoires non stéroïdiens (AINS) tels que l'acide méfénamique, l', l' ou l'acide méclofénamique, les acides fénamiques (ou acides N-arylanthraniliques). Toutefois, un certain nombre de composés classés dans cette famille pharmacologique ne sont pas stricto sensu des dérivés de l'acide fénamique, comme la par exemple. (fr) |
| rdfs:label | Ácido fenámico (es) Fenamic acid (en) Acide fénamique (fr) フェナム酸 (ja) Ácido fenâmico (pt) 芬那酸 (zh) |
| owl:sameAs | freebase:Fenamic acid yago-res:Fenamic acid wikidata:Fenamic acid http://azb.dbpedia.org/resource/فنامیک_اسید dbpedia-es:Fenamic acid dbpedia-fa:Fenamic acid dbpedia-fi:Fenamic acid dbpedia-fr:Fenamic acid dbpedia-hu:Fenamic acid dbpedia-ja:Fenamic acid dbpedia-pt:Fenamic acid dbpedia-ro:Fenamic acid dbpedia-sh:Fenamic acid dbpedia-sr:Fenamic acid dbpedia-zh:Fenamic acid https://global.dbpedia.org/id/4cwjQ |
| prov:wasDerivedFrom | wikipedia-en:Fenamic_acid?oldid=1024222231&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Fenamic_acid.png wiki-commons:Special:FilePath/Fenamic_acid_3D_ball.png |
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