Forssman antigen (original) (raw)
The Forssman antigen is a glycolipid heterophil protein and a type of heterogenetic antigen found in certain animals like dogs, horses, cats, turtles and sheep, and enteric organisms such as pneumococci. In sheep, it is found on erythrocytes but not on tissue and organs, unlike hamsters and guinea pigs whose organ cells do carry the antigen. The Forssman antigen is distinct from the Paul-Bunnell antigen, antibodies to which are diagnostic of glandular fever (infectious mononucleosis). Both antigens are present on the red blood cells of horse and sheep but guinea pig kidney cells have only the Forssman antigen. A serum positive for glandular fever therefore agglutinates horse or sheep red blood cells after absorption with guinea pig kidney.
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| dbo:abstract | The Forssman antigen is a glycolipid heterophil protein and a type of heterogenetic antigen found in certain animals like dogs, horses, cats, turtles and sheep, and enteric organisms such as pneumococci. In sheep, it is found on erythrocytes but not on tissue and organs, unlike hamsters and guinea pigs whose organ cells do carry the antigen. The Forssman antigen is distinct from the Paul-Bunnell antigen, antibodies to which are diagnostic of glandular fever (infectious mononucleosis). Both antigens are present on the red blood cells of horse and sheep but guinea pig kidney cells have only the Forssman antigen. A serum positive for glandular fever therefore agglutinates horse or sheep red blood cells after absorption with guinea pig kidney. (en) フォルスマン抗原（フォルスマンこうげん、英: Forssman Antigen）は、糖脂質異好タンパク質であり、肺炎レンサ球菌といった腸内微生物を含むイヌやウマ、ネコ、カメ、ヒツジのような特定の動物において見られる異種抗原の一種である。ヒツジでは、赤血球において見られるが、組織および器官では見られない。フォルスマン抗原はポール・バンネル抗原（伝染性単核球症の特徴）とは異なる。どちらの抗原もウマおよびヒツジの赤血球上に存在するが、モルモットの腎細胞はフォルスマン抗原のみを有する。したがって伝染性単核球症陽性の血清は、モルモット腎臓を吸収した後、ウマまたはヒツジ赤血球を凝集させる。 名称は1930年にこの抗原について記述したスウェーデンの病理学者John Frederick Forssman (1868 – 1947) に因む。 (ja) |
| dbo:wikiPageExternalLink | http://medical-dictionary.thefreedictionary.com/Forssman+antigen%7Ctitle=Forssman http://www.whonamedit.com/doctor.cfm/1838.html%7Ctitle=Whonamedit http://www.merriam-webster.com/dictionary/forssman%20antigen%7Ctitle=Forssman http://www.medilexicon.com/medicaldictionary.php%3Ft=4863%7Ctitle=Forssman |
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| dbo:wikiPageLength | 2130 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 956390938 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Antigen dbc:Immunology dbr:Protein dbr:Red_blood_cell dbr:Streptococcus_pneumoniae dbr:Infectious_mononucleosis |
| dbp:wikiPageUsesTemplate | dbt:Cite_web dbt:External_links dbt:Multiple_issues dbt:No_footnotes dbt:Reflist |
| dct:subject | dbc:Immunology |
| gold:hypernym | dbr:Protein |
| rdf:type | dbo:Protein |
| rdfs:comment | The Forssman antigen is a glycolipid heterophil protein and a type of heterogenetic antigen found in certain animals like dogs, horses, cats, turtles and sheep, and enteric organisms such as pneumococci. In sheep, it is found on erythrocytes but not on tissue and organs, unlike hamsters and guinea pigs whose organ cells do carry the antigen. The Forssman antigen is distinct from the Paul-Bunnell antigen, antibodies to which are diagnostic of glandular fever (infectious mononucleosis). Both antigens are present on the red blood cells of horse and sheep but guinea pig kidney cells have only the Forssman antigen. A serum positive for glandular fever therefore agglutinates horse or sheep red blood cells after absorption with guinea pig kidney. (en) フォルスマン抗原（フォルスマンこうげん、英: Forssman Antigen）は、糖脂質異好タンパク質であり、肺炎レンサ球菌といった腸内微生物を含むイヌやウマ、ネコ、カメ、ヒツジのような特定の動物において見られる異種抗原の一種である。ヒツジでは、赤血球において見られるが、組織および器官では見られない。フォルスマン抗原はポール・バンネル抗原（伝染性単核球症の特徴）とは異なる。どちらの抗原もウマおよびヒツジの赤血球上に存在するが、モルモットの腎細胞はフォルスマン抗原のみを有する。したがって伝染性単核球症陽性の血清は、モルモット腎臓を吸収した後、ウマまたはヒツジ赤血球を凝集させる。 名称は1930年にこの抗原について記述したスウェーデンの病理学者John Frederick Forssman (1868 – 1947) に因む。 (ja) |
| rdfs:label | Forssman antigen (en) フォルスマン抗原 (ja) |
| owl:sameAs | freebase:Forssman antigen wikidata:Forssman antigen http://bs.dbpedia.org/resource/Forssman_sistem_antigena dbpedia-ja:Forssman antigen https://global.dbpedia.org/id/fZ3X |
| prov:wasDerivedFrom | wikipedia-en:Forssman_antigen?oldid=956390938&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Forssman_antigen |
| is dbo:wikiPageWikiLink of | dbr:List_of_MeSH_codes_(D23) dbr:Index_of_immunology_articles dbr:GBGT1 dbr:John_Forssman dbr:Charles_Arthur_Stuart dbr:Heterophile_antigen dbr:P_fimbriae |
| is foaf:primaryTopic of | wikipedia-en:Forssman_antigen |