FtsK (original) (raw)

FtsK is a 1329 amino acid protein involved in bacterial cell division and chromosome segregation. FtsK stands for "Filament temperature sensitive mutant K" because at high temperatures the mutant bacterial cell fails to divide and long filaments develop instead. FtsK, and specifically its C-domain, functions as DNA pump, interacts with other cell division proteins, and intervenes in the regulation of the Xer recombination process. FtsK belongs to the AAA (ATPase Associated with various cellular Activities) superfamily and is present in most bacteria.