Glabrene (original) (raw)
Glabrene is an isoflavonoid that is found in Glycyrrhiza glabra (licorice). It has estrogenic activity, showing estrogenic effects on breast, vascular, and bone tissue, and hence is a phytoestrogen (IC50 for estrogen receptor binding = 1 μM). It has also been found to act as a tyrosinase inhibitor (IC50 = 3.5 μM) and to inhibit the formation of melanin in melanocytes, and for these reasons, has been suggested as a potential skin-lightening agent.
| Property | Value |
|---|---|
| dbo:abstract | Glabrene is an isoflavonoid that is found in Glycyrrhiza glabra (licorice). It has estrogenic activity, showing estrogenic effects on breast, vascular, and bone tissue, and hence is a phytoestrogen (IC50 for estrogen receptor binding = 1 μM). It has also been found to act as a tyrosinase inhibitor (IC50 = 3.5 μM) and to inhibit the formation of melanin in melanocytes, and for these reasons, has been suggested as a potential skin-lightening agent. (en) |
| dbo:alternativeName | 2',2'-dimethyl-2H,2'H-3,8'-bichromene-5',7-diol (en) |
| dbo:iupacName | 2′,2′-Dimethyl-2H,2′H-[3,8′-bi-1-benzopyran]-5′,7-diol (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Glabrene.svg?width=300 |
| dbo:wikiPageID | 52625088 (xsd:integer) |
| dbo:wikiPageLength | 3311 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1024341398 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Enzyme_inhibitor dbr:Bone dbr:Breast dbr:Melanin dbr:Melanocyte dbr:Estrogen dbr:Glabridin dbr:Glycyrrhiza_glabra dbr:Liquiritigenin dbc:Isoflavonoids dbc:Phytoestrogens dbr:Estrogen_receptor dbr:Isoflavonoid dbr:Isoliquiritigenin dbr:Tissue_(biology) dbr:Tyrosinase dbr:IC50 dbr:Phytoestrogen dbr:Vascular_system |
| dbp:imagefile | Glabrene.svg (en) |
| dbp:imagesize | 250 (xsd:integer) |
| dbp:othernames | -300.0 |
| dbp:pin | 2 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Phytoestrogens dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Estrogen_receptor_modulators dbt:Organic-compound-stub dbt:Reflist |
| dcterms:subject | dbc:Isoflavonoids dbc:Phytoestrogens |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound |
| rdfs:comment | Glabrene is an isoflavonoid that is found in Glycyrrhiza glabra (licorice). It has estrogenic activity, showing estrogenic effects on breast, vascular, and bone tissue, and hence is a phytoestrogen (IC50 for estrogen receptor binding = 1 μM). It has also been found to act as a tyrosinase inhibitor (IC50 = 3.5 μM) and to inhibit the formation of melanin in melanocytes, and for these reasons, has been suggested as a potential skin-lightening agent. (en) |
| rdfs:label | Glabrene (en) |
| owl:sameAs | wikidata:Glabrene https://global.dbpedia.org/id/2Ybid |
| prov:wasDerivedFrom | wikipedia-en:Glabrene?oldid=1024341398&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Glabrene.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Glabrene |
| is dbo:wikiPageWikiLink of | dbr:C20H18O4 dbr:Liquorice dbr:Glabridin dbr:Isoflavene |
| is foaf:primaryTopic of | wikipedia-en:Glabrene |
