GlmZ RNA (original) (raw)

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dbo:abstract GlmZ (formally known as SraJ) is a small non-coding RNA (ncRNA). It is the functional product of a gene which is not translated into protein. This ncRNA was discovered in the bacteria Escherichia coli during a large scale computational screen for transcription signals and genomic features of known small RNA-encoding genes. During this screen 14 novel ncRNA genes were identified, including SraB, SraC, SraD and SraG. The expression of SraJ was experimentally confirmed by Northern blotting. This ncRNA is expressed in early logarithmic phase, but its level decreases into stationary phase. Northern blot analysis also indicated this RNA undergoes specific cleavage processing. The GlmZ sRNA has been shown to positively control the synthesis of mRNA. GlmZ is regulated by a related sRNA called GlmY. GlmY functions as an anti-adaptor, it binds to RapZ (RNase adaptor protein for sRNA GlmZ), this binding prevents RapZ from binding to GlmZ and targeting it for cleavage by RNase E. (en)
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dbo:wikiPageRevisionID 1035461331 (xsd:integer)
dbo:wikiPageWikiLink dbr:MRNA dbr:Gene dbr:GlmY_RNA dbr:Bacteria dbc:Non-coding_RNA dbr:Escherichia_coli dbr:Protein dbr:Bacterial_growth dbr:Bacterial_small_RNA dbr:SraB_RNA dbr:SraC/RyeA_RNA dbr:SraG_RNA dbr:Sequence_conservation dbr:Non-coding_RNA dbr:Secondary_structure dbr:RNase dbr:Northern_blotting dbr:SraD_RNA dbr:Glucosamine_synthase
dbp:altsymbols SraJ (en)
dbp:caption Predicted secondary structure and sequence conservation of GlmZ_SraJ (en)
dbp:id RF00083 (en)
dbp:name GlmZ RNA activator of glmS mRNA (en) SraJ RNA (en)
dbp:rfam RF00083 (en)
dbp:rnaType dbr:Gene dbr:Bacterial_small_RNA
dbp:symbol GlmZ_SraJ (en)
dbp:taxDomain dbr:Bacteria
dbp:wikiPageUsesTemplate dbt:Reflist dbt:Short_description dbt:SO dbt:Infobox_rfam dbt:Molecular-cell-biology-stub dbt:Rfam
dcterms:subject dbc:Non-coding_RNA
gold:hypernym dbr:RNA
rdf:type dbo:Protein
rdfs:comment GlmZ (formally known as SraJ) is a small non-coding RNA (ncRNA). It is the functional product of a gene which is not translated into protein. This ncRNA was discovered in the bacteria Escherichia coli during a large scale computational screen for transcription signals and genomic features of known small RNA-encoding genes. During this screen 14 novel ncRNA genes were identified, including SraB, SraC, SraD and SraG. (en)
rdfs:label GlmZ RNA (en)
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prov:wasDerivedFrom wikipedia-en:GlmZ_RNA?oldid=1035461331&ns=0
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is dbo:wikiPageRedirects of dbr:SraJ_RNA
is dbo:wikiPageWikiLink of dbr:GLM dbr:ArcZ_RNA dbr:SraG_RNA dbr:SraJ_RNA
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