Haplotype block (original) (raw)
In genetics, a haplotype block is a region of an organism's genome in which there is little evidence of a history of genetic recombination, and which contain only a small number of distinct haplotypes. According to the haplotype-block model, such blocks should show high levels of linkage disequilibrium and be separated from one another by numerous recombination events. The boundaries of haplotype blocks cannot be directly observed; they must instead be inferred indirectly through the use of algorithms. However, some evidence suggests that different algorithms for identifying haplotype blocks give very different results when used on the same data, though another study suggests that their results are generally consistent. The National Institutes of Health funded the HapMap project to catalog
| Property | Value |
|---|---|
| dbo:abstract | In genetics, a haplotype block is a region of an organism's genome in which there is little evidence of a history of genetic recombination, and which contain only a small number of distinct haplotypes. According to the haplotype-block model, such blocks should show high levels of linkage disequilibrium and be separated from one another by numerous recombination events. The boundaries of haplotype blocks cannot be directly observed; they must instead be inferred indirectly through the use of algorithms. However, some evidence suggests that different algorithms for identifying haplotype blocks give very different results when used on the same data, though another study suggests that their results are generally consistent. The National Institutes of Health funded the HapMap project to catalog haplotype blocks throughout the human genome. (en) |
| dbo:wikiPageID | 59797213 (xsd:integer) |
| dbo:wikiPageLength | 5660 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1006768045 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Algorithm dbc:Biology_terminology dbc:Genomics dbr:Genetic_recombination dbr:Genetics dbr:Genome dbr:Linkage_disequilibrium dbr:Haplotype dbr:Human_genome dbr:National_Institutes_of_Health dbr:HapMap dbr:Single_nucleotide_polymorphism |
| dbp:wikiPageUsesTemplate | dbt:Reflist dbt:Short_description dbt:Genetics-stub |
| dct:subject | dbc:Biology_terminology dbc:Genomics |
| rdfs:comment | In genetics, a haplotype block is a region of an organism's genome in which there is little evidence of a history of genetic recombination, and which contain only a small number of distinct haplotypes. According to the haplotype-block model, such blocks should show high levels of linkage disequilibrium and be separated from one another by numerous recombination events. The boundaries of haplotype blocks cannot be directly observed; they must instead be inferred indirectly through the use of algorithms. However, some evidence suggests that different algorithms for identifying haplotype blocks give very different results when used on the same data, though another study suggests that their results are generally consistent. The National Institutes of Health funded the HapMap project to catalog (en) |
| rdfs:label | Haplotype block (en) |
| owl:sameAs | wikidata:Haplotype block https://global.dbpedia.org/id/AR3gy |
| prov:wasDerivedFrom | wikipedia-en:Haplotype_block?oldid=1006768045&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Haplotype_block |
| is dbo:wikiPageWikiLink of | dbr:Tag_SNP dbr:Uncharacterized_protein_C15orf32 |
| is foaf:primaryTopic of | wikipedia-en:Haplotype_block |