| dbo:abstract |
Hycanthone is the schistosomicide approved by the FDA in 1975. It is a metabolite of lucanthone. Hycanthone interferes with parasite nerve function, resulting in paralysis and death. This agent also intercalates into DNA and inhibits RNA synthesis in vitro and shows potential antineoplastic activity. (en) La hicantona es agente antiesquistosomal efectivo, análogo a la tioxantona y metabolito de la lucantona. (es) |
| dbo:casNumber |
3105-97-3 |
| dbo:chEBI |
52768 |
| dbo:chEMBL |
22077 |
| dbo:fdaUniiCode |
2BXX5EVN2A |
| dbo:kegg |
D00541 |
| dbo:pubchem |
3634 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Hycanthone.png?width=300 |
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| dbo:wikiPageLength |
4579 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
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| dbo:wikiPageWikiLink |
dbr:In_vitro dbr:Intercalation_(biochemistry) dbr:Melting_point dbr:Antineoplastic dbr:Lucanthone dbr:Paralysis dbr:State_of_matter dbr:Acetylcholinesterase dbr:Parasite dbr:Partition_coefficient dbc:Diethylamino_compounds dbc:Antiparasitic_agents dbc:Thioxanthones dbr:Solubility dbr:Schistosoma_mansoni dbr:Schistosomicide dbr:Absorption_maximum |
| dbp:atcPrefix |
none (en) |
| dbp:c |
20 (xsd:integer) |
| dbp:casNumber |
3105 (xsd:integer) |
| dbp:chebi |
52768 (xsd:integer) |
| dbp:chembl |
22077 (xsd:integer) |
| dbp:chemspiderid |
3508 (xsd:integer) |
| dbp:h |
24 (xsd:integer) |
| dbp:iupacName |
1 (xsd:integer) |
| dbp:kegg |
D00541 (en) |
| dbp:n |
2 (xsd:integer) |
| dbp:o |
2 (xsd:integer) |
| dbp:pubchem |
3634 (xsd:integer) |
| dbp:s |
1 (xsd:integer) |
| dbp:smiles |
CCNCCNC1=C2CSC3=CC=CC=C3C2=O (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
MFZWMTSUNYWVBU-UHFFFAOYSA-N (en) |
| dbp:unii |
2 (xsd:integer) |
| dbp:verifiedfields |
changed (en) |
| dbp:verifiedrevid |
407389823 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Anthelmintics |
| dcterms:subject |
dbc:Diethylamino_compounds dbc:Antiparasitic_agents dbc:Thioxanthones |
| gold:hypernym |
dbr:Schistosomicide |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAntiparasiticAgents yago:Agent109190918 yago:CausalAgent100007347 yago:PhysicalEntity100001930 dbo:Drug umbel-rc:DrugProduct |
| rdfs:comment |
Hycanthone is the schistosomicide approved by the FDA in 1975. It is a metabolite of lucanthone. Hycanthone interferes with parasite nerve function, resulting in paralysis and death. This agent also intercalates into DNA and inhibits RNA synthesis in vitro and shows potential antineoplastic activity. (en) La hicantona es agente antiesquistosomal efectivo, análogo a la tioxantona y metabolito de la lucantona. (es) |
| rdfs:label |
Hicantona (es) Hycanthone (en) |
| owl:sameAs |
freebase:Hycanthone yago-res:Hycanthone wikidata:Hycanthone dbpedia-es:Hycanthone dbpedia-sh:Hycanthone dbpedia-sr:Hycanthone https://global.dbpedia.org/id/4mywy |
| prov:wasDerivedFrom |
wikipedia-en:Hycanthone?oldid=1072223333&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Hycanthone.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Hycanthone |
| is dbo:wikiPageWikiLink of |
dbr:List_of_drugs_used_to_treat_schistosomiasis dbr:Thioxanthone dbr:Lucanthone dbr:List_of_MeSH_codes_(D03) dbr:Schistosoma_bovis dbr:List_of_drugs:_Hf–Hz |
| is foaf:primaryTopic of |
wikipedia-en:Hycanthone |
