| dbo:abstract |
The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer, and consists of two subunits, interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various cytokines, including interleukin-2, -4, -9, and -15. Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others. (en) |
| dbo:arm |
p q |
| dbo:band |
13 |
| dbo:chromosome |
5 X |
| dbo:entrezgene |
3561 3575 |
| dbo:hgncid |
6024 6010 |
| dbo:omim |
146661 (xsd:integer) 308380 (xsd:integer) |
| dbo:refseq |
NM_000206 NM_002185 |
| dbo:symbol |
IL2RG SCIDX1, IMD4, CD132 CD127 IL7R |
| dbo:thumbnail |
wiki-commons:Special:FilePath/IL-7receptor_and_signaling.jpg?width=300 |
| dbo:uniprot |
P31785 P16871 |
| dbo:wikiPageID |
14156041 (xsd:integer) |
| dbo:wikiPageLength |
6086 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1079538513 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Rheumatoid_arthritis dbr:Interleukin-7_receptor-α dbr:Interleukin_2 dbr:Interleukin_7 dbr:Genome dbr:STAT5 dbr:Multiple_sclerosis dbr:Cluster_of_differentiation dbc:Type_I_cytokine_receptors dbr:T-cell_receptor dbr:Cell_(biology) dbr:Juvenile_idiopathic_arthritis dbr:Alpha_helix dbr:Protein dbr:T-lymphoblastic_leukemia/lymphoma dbr:C-terminus dbr:IL2RB dbr:Naive_T_cells dbr:IL2RA dbr:N-terminus dbr:V(D)J_recombination dbr:Interleukin-4 dbr:Memory_T_cells dbr:IL2RG dbr:Heterodimer dbr:Interleukin-15 dbr:Interleukin-2 dbr:Interleukin-9 dbr:CD127 dbr:CD132 dbr:File:IL-7receptor_and_signaling.jpg |
| dbp:altsymbols |
CD127 (en) SCIDX1, IMD4, CD132 (en) |
| dbp:arm |
p (en) q (en) |
| dbp:band |
13 (xsd:integer) |
| dbp:chromosome |
5 (xsd:integer) X (en) |
| dbp:entrezgene |
3561 (xsd:integer) 3575 (xsd:integer) |
| dbp:hgncid |
6010 (xsd:integer) 6024 (xsd:integer) |
| dbp:imageSource |
Crystallographic structure of IL-2 complexed with the common gamma chain , IL2RA , and IL2RB . Each protein is individually rainbow colored . (en) |
| dbp:name |
dbr:Interleukin-7_receptor-α dbr:IL2RG |
| dbp:omim |
146661 (xsd:integer) 308380 (xsd:integer) |
| dbp:refseq |
NM_000206 (en) NM_002185 (en) |
| dbp:symbol |
dbr:Interleukin-7_receptor-α dbr:IL2RG |
| dbp:uniprot |
P31785 (en) P16871 (en) |
| dbp:wikiPageUsesTemplate |
dbt:Citation_needed dbt:MeshName dbt:Reflist dbt:Short_description dbt:Interleukin_receptor_modulators dbt:Infobox_protein dbt:NLM_content dbt:Clusters_of_differentiation_by_lineage dbt:Cytokine_receptors |
| dcterms:subject |
dbc:Type_I_cytokine_receptors |
| gold:hypernym |
dbr:Protein |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:WikicatTypeICytokineReceptors yago:BodyPart105220461 yago:Part109385911 yago:PhysicalEntity100001930 yago:Receptor105608868 dbo:Protein yago:Structure105225602 yago:Thing100002452 |
| rdfs:comment |
The interleukin-7 receptor is a protein found on the surface of cells. It is made up of two different smaller protein chains - i.e. it is a heterodimer, and consists of two subunits, interleukin-7 receptor-α (CD127) and common-γ chain receptor (CD132). The common-γ chain receptors is shared with various cytokines, including interleukin-2, -4, -9, and -15. Interleukin-7 receptor is expressed on various cell types, including naive and memory T cells and many others. (en) |
| rdfs:label |
Interleukin-7 receptor (en) |
| owl:sameAs |
freebase:Interleukin-7 receptor wikidata:Interleukin-7 receptor dbpedia-fi:Interleukin-7 receptor https://global.dbpedia.org/id/4nqMf |
| prov:wasDerivedFrom |
wikipedia-en:Interleukin-7_receptor?oldid=1079538513&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Protein_IL2RG_PDB_2b5i.png wiki-commons:Special:FilePath/IL-7receptor_and_signaling.jpg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Interleukin-7_receptor |
| foaf:name |
Interleukin-7 receptor-α (en) interleukin 2 receptor, gamma (en) |
| is dbo:wikiPageRedirects of |
dbr:IL-7_receptor dbr:IL7R dbr:Interleukin-7_receptors dbr:Interleukin_7_receptor dbr:CDW127 |
| is dbo:wikiPageWikiLink of |
dbr:Nasal-associated_lymphoid_tissue dbr:Index_of_immunology_articles dbr:Interleukin dbr:Interleukin-7_receptor-α dbr:Interleukin_7 dbr:Naive_T_cell dbr:Common_gamma_chain dbr:TBR1 dbr:NFAT dbr:IL-7_receptor dbr:IL7R dbr:Interleukin-7_receptors dbr:Interleukin_7_receptor dbr:CDW127 |
| is foaf:primaryTopic of |
wikipedia-en:Interleukin-7_receptor |
