JWH-370 (original) (raw)

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dbo:abstract JWH-370 ([5-(2-methylphenyl)-1-pentylpyrrol-3-yl]-naphthalen-1-ylmethanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB1 (Ki = 5.6 ± 0.4nM) and CB2 (Ki = 4.0 ± 0.5nM) receptors, with a slight selectivity for the CB2 receptor. JWH-370 was first synthesized in 2006 by John W. Huffman and colleagues to examine the nature of ligand binding to the CB1 receptor. (en)
dbo:casNumber 914458-22-3
dbo:fdaUniiCode HJZ9JN4HNM
dbo:pubchem 44418312
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dbo:wikiPageID 68529351 (xsd:integer)
dbo:wikiPageLength 3942 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID 1102142815 (xsd:integer)
dbo:wikiPageWikiLink dbr:John_W._Huffman dbc:Designer_drugs dbr:Controlled_Drugs_and_Substances_Act dbc:JWH_cannabinoids dbr:List_of_JWH_cannabinoids dbr:Misuse_of_Drugs_Act_1971 dbc:CB1_receptor_agonists dbc:CB2_receptor_agonists dbr:Synthetic_cannabinoid dbc:Naphthoylpyrroles dbr:Cannabinoid_receptor_1 dbr:Cannabinoid_receptor_2
dbp:c 27 (xsd:integer)
dbp:casNumber 914458 (xsd:integer)
dbp:chemspiderid 23277889 (xsd:integer)
dbp:h 27 (xsd:integer)
dbp:iupacName [5--1-pentylpyrrol-3-yl]-naphthalen-1-ylmethanone (en)
dbp:legalCa Schedule II (en)
dbp:legalUk Class B (en)
dbp:n 1 (xsd:integer)
dbp:o 1 (xsd:integer)
dbp:pubchem 44418312 (xsd:integer)
dbp:smiles CCCCCN1C=CCC3=CC=CC4=CC=CC=C43 (en)
dbp:stdinchi 1 (xsd:integer)
dbp:stdinchikey HZMLAMXVETUEJZ-UHFFFAOYSA-N (en)
dbp:unii HJZ9JN4HNM (en)
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dct:subject dbc:Designer_drugs dbc:JWH_cannabinoids dbc:CB1_receptor_agonists dbc:CB2_receptor_agonists dbc:Naphthoylpyrroles
rdf:type owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment JWH-370 ([5-(2-methylphenyl)-1-pentylpyrrol-3-yl]-naphthalen-1-ylmethanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB1 (Ki = 5.6 ± 0.4nM) and CB2 (Ki = 4.0 ± 0.5nM) receptors, with a slight selectivity for the CB2 receptor. JWH-370 was first synthesized in 2006 by John W. Huffman and colleagues to examine the nature of ligand binding to the CB1 receptor. (en)
rdfs:label JWH-370 (en)
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