Jennifer Lippincott-Schwartz (original) (raw)
Дженнифер Липпинкотт-Шварц (Jennifer A. Lippincott-Schwartz; род. 19 октября 1952, Манхэттен, Канзас) — американский цитолог, исследовательница органелл.Доктор философии, групп-лидер (с 2016), перед чем более 30 лет провела в Национальных институтах здравоохранения. Член Национальных Академии наук (2008) и (2009) США.
| Property | Value |
|---|---|
| dbo:abstract | Jennifer Lippincott-Schwartz is a Senior Group Leader at Howard Hughes Medical Institute's Janelia Research Campus and a founding member of the Neuronal Cell Biology Program at Janelia. Previously, she was the Chief of the Section on Organelle Biology in the Cell Biology and Metabolism Program, in the Division of Intramural Research in the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health from 1993 to 2016. Lippincott-Schwartz received her PhD from Johns Hopkins University, and performed post-doctoral training with Richard Klausner at the NICHD, NIH in Bethesda, Maryland. Lippincott-Schwartz's research revealed that the organelles of eukaryotic cells are dynamic, self-organized structures that constantly regenerate themselves through intracellular vesicle traffic, rather than static structures. She is also a pioneer in developing live cell imaging techniques to study the dynamic interactions of molecules in cells, including photobleaching and photoactivation techniques which allow investigation of subcellular localization, mobility, transport routes, and turnover of important cellular proteins related to membrane trafficking and compartmentalization. Lippincott-Schwartz's lab also tests mechanistic hypotheses related to protein and organelle functions and dynamics by utilizing quantitative measurements through kinetic modeling and simulation experiments. Along with Craig Blackstone, Lippincott-Schwartz utilized advanced imaging techniques to reveal a more accurate picture of how the peripheral endoplasmic reticulum is structured. Their findings may yield new insights for genetic diseases affecting proteins that help shape the endoplasmic reticulum. Additionally, Lippincott-Schwartz's laboratory demonstrated that Golgi enzymes constitutively recycle back to the endoplasmic reticulum and that such recycling plays a central role in the maintenance, biogenesis, and inheritance of the Golgi apparatus in mammalian cells. Within Lippincott-Schwartz lab, current projects include several cell biological areas. For example, protein transport and cytoskeleton interaction, organelle assembly and disassembly, and cell polarity generation. There are also projects analyzing the dynamics of proteins that have been fluorescently labeled. These proteins are labeled using several live cell imaging techniques such as FRAP, FCS, and photoactivation. Lippincott-Schwartz has dedicated her most recent lab research to photoactivation localization microscopy (PALM), which allows the viewing of molecular distributions of high densities at the nano-scale. (en) Дженнифер Липпинкотт-Шварц (Jennifer A. Lippincott-Schwartz; род. 19 октября 1952, Манхэттен, Канзас) — американский цитолог, исследовательница органелл.Доктор философии, групп-лидер (с 2016), перед чем более 30 лет провела в Национальных институтах здравоохранения. Член Национальных Академии наук (2008) и (2009) США. (ru) |
| dbo:almaMater | dbr:Johns_Hopkins_University dbr:Swarthmore_College |
| dbo:birthDate | 1952-10-19 (xsd:date) |
| dbo:birthName | Jennifer Lippincott (en) |
| dbo:institution | dbr:Eunice_Kennedy_Shriver_National_Institute_of_Child_Health_and_Human_Development |
| dbo:thumbnail | wiki-commons:Special:FilePath/Jennifer-Lippincott-Schwartz.jpg?width=300 |
| dbo:wikiPageExternalLink | https://www.youtube.com/watch%3Fv=FPCqvdsnJwQ http://annualreport.nichd.nih.gov/lippincottschwartz.html https://science.nichd.nih.gov/confluence/display/sob/Home/ https://www.youtube.com/watch%3Fv=Bom9d-Knz0w https://www.youtube.com/watch%3Fv=bhjP9PqfJRE http://www.nichd.nih.gov/news/profiles/researchers/lippincott-schwartz/Pages/default.aspx https://www.janelia.org/lab/lippincott-schwartz-lab http://www.nih.gov/ |
| dbo:wikiPageID | 22729563 (xsd:integer) |
| dbo:wikiPageLength | 23286 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1122731220 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Endoplasmic_reticulum dbr:Brefeldin_A dbr:Howard_Hughes_Medical_Institute dbr:Johns_Hopkins_University dbc:1952_births dbc:21st-century_American_women dbc:Living_people dbr:Stanford_University dbc:21st-century_American_biologists dbc:Members_of_the_National_Academy_of_Medicine dbr:American_Society_for_Cell_Biology dbr:E.B._Wilson_Medal dbr:Eric_Betzig dbr:Eukaryote dbr:Eunice_Kennedy_Shriver_National_Institute_of_Child_Health_and_Human_Development dbr:Fluorescence_recovery_after_photobleaching dbr:Golgi_apparatus dbr:Janelia_Research_Campus dbc:American_women_scientists dbc:Fellows_of_the_Royal_Microscopical_Society dbr:Swarthmore_College dbr:Philip_Hanawalt dbr:Green_fluorescent_protein dbr:National_Academy_of_Sciences dbr:National_Institutes_of_Health dbr:Photobleaching dbr:University_of_Maryland dbr:Photoactivated_localization_microscopy dbr:Janelia_Farm_Research_Campus dbr:National_Institute_of_Child_Health_and_Human_Development dbr:File:Jennifer_Lippincott-Schwartz_(33059648222).jpg |
| dbp:almaMater | Johns Hopkins University (en) Swarthmore College (en) (en) |
| dbp:alt | ALT IMAGE TEXT (en) |
| dbp:birthDate | 1952-10-19 (xsd:date) |
| dbp:birthName | Jennifer Lippincott (en) |
| dbp:birthPlace | Manhattan, Kansas (en) |
| dbp:fields | (en) Organelle Biology (en) |
| dbp:knownFor | (en) |
| dbp:name | Jennifer Lippincott-Schwartz (en) |
| dbp:spouse | Jonathan Schwartz (en) |
| dbp:wikiPageUsesTemplate | dbt:E.B._Wilson_Medal_recipients dbt:Authority_control dbt:Reflist dbt:Short_description dbt:Use_mdy_dates dbt:Birth_date_and_age dbt:Infobox_scientist |
| dbp:workplaces | (en) Eunice Kennedy Shriver National Institute of Child Health and Human Development (en) |
| dcterms:subject | dbc:1952_births dbc:21st-century_American_women dbc:Living_people dbc:21st-century_American_biologists dbc:Members_of_the_National_Academy_of_Medicine dbc:American_women_scientists dbc:Fellows_of_the_Royal_Microscopical_Society |
| gold:hypernym | dbr:Chief |
| rdf:type | owl:Thing foaf:Person dbo:Person dul:NaturalPerson wikidata:Q19088 wikidata:Q215627 wikidata:Q5 wikidata:Q729 yago:WikicatAmericanBiologists dbo:Animal dbo:Eukaryote dbo:Scientist dbo:Species schema:Person yago:WikicatLivingPeople wikidata:Q901 yago:Biologist109855630 yago:CausalAgent100007347 yago:LivingThing100004258 yago:Object100002684 yago:Organism100004475 yago:Person100007846 yago:PhysicalEntity100001930 yago:YagoLegalActor yago:YagoLegalActorGeo yago:Scientist110560637 yago:Whole100003553 |
| rdfs:comment | Дженнифер Липпинкотт-Шварц (Jennifer A. Lippincott-Schwartz; род. 19 октября 1952, Манхэттен, Канзас) — американский цитолог, исследовательница органелл.Доктор философии, групп-лидер (с 2016), перед чем более 30 лет провела в Национальных институтах здравоохранения. Член Национальных Академии наук (2008) и (2009) США. (ru) Jennifer Lippincott-Schwartz is a Senior Group Leader at Howard Hughes Medical Institute's Janelia Research Campus and a founding member of the Neuronal Cell Biology Program at Janelia. Previously, she was the Chief of the Section on Organelle Biology in the Cell Biology and Metabolism Program, in the Division of Intramural Research in the Eunice Kennedy Shriver National Institute of Child Health and Human Development at the National Institutes of Health from 1993 to 2016. Lippincott-Schwartz received her PhD from Johns Hopkins University, and performed post-doctoral training with Richard Klausner at the NICHD, NIH in Bethesda, Maryland. (en) |
| rdfs:label | Jennifer Lippincott-Schwartz (en) Липпинкотт-Шварц, Дженнифер (ru) |
| owl:sameAs | freebase:Jennifer Lippincott-Schwartz yago-res:Jennifer Lippincott-Schwartz http://d-nb.info/gnd/1082094706 http://viaf.org/viaf/19019387 https://orcid.org/0000-0002-8601-3501 wikidata:Jennifer Lippincott-Schwartz http://azb.dbpedia.org/resource/جنیفر_لیپین_کت_شوارتز dbpedia-ru:Jennifer Lippincott-Schwartz https://global.dbpedia.org/id/4oQqh |
| prov:wasDerivedFrom | wikipedia-en:Jennifer_Lippincott-Schwartz?oldid=1122731220&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Jennifer-Lippincott-Schwartz.jpg wiki-commons:Special:FilePath/Jennifer_Lippincott-Schwartz_(33059648222).jpg |
| foaf:isPrimaryTopicOf | wikipedia-en:Jennifer_Lippincott-Schwartz |
| foaf:name | Jennifer Lippincott-Schwartz (en) |
| is dbo:wikiPageWikiLink of | dbr:List_of_members_of_the_National_Academy_of_Medicine dbr:List_of_people_from_Manhattan,_Kansas dbr:List_of_members_of_the_National_Academ..._(Cellular_and_developmental_biology) dbr:Fritiof_S._Sjöstrand dbr:Annual_Review_of_Cell_and_Developmental_Biology dbr:List_of_American_Academy_of_Arts_and_Sciences_members_(2006–2019) dbr:American_Society_for_Cell_Biology dbr:E.B._Wilson_Medal dbr:Keith_R._Porter_Lecture dbr:Janelia_Research_Campus dbr:Suliana_Manley dbr:Association_of_Biomolecular_Resource_Facilities |
| is foaf:primaryTopic of | wikipedia-en:Jennifer_Lippincott-Schwartz |
