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جون س. شيهان (بالإنجليزية: John C. Sheehan) هو أستاذ جامعي وكيميائي أمريكي، ولد في 23 سبتمبر 1915 في باتل كريك في الولايات المتحدة، وتوفي في 21 مارس 1992 في كي بيسكاين في الولايات المتحدة. (ar) John Clark Sheehan (* 23. September 1915; † 21. März 1992) war ein US-amerikanischer Chemiker und Professor für Organische Chemie am Massachusetts Institute of Technology (MIT). (de) John Clark Sheehan (September 23, 1915 – March 21, 1992) was an American organic chemist whose work on synthetic penicillin led to tailor-made forms of the drug. After nine years of hard work at the Massachusetts Institute of Technology (M.I.T.), he became the first to discover a practical method for synthesizing penicillin V. While achieving total synthesis, Sheehan also produced an intermediate compound, 6-aminopenicillanic acid, which turned out to be the foundation of hundreds of kinds of synthetic penicillin. Dr. Sheehan's research on synthetic penicillin paved the way for the development of customized forms of the lifesaving antibiotic that target specific bacteria. Over the four decades he worked at M.I.T., Sheehan came to hold over 30 patents, including the invention of ampicillin, a commonly used semi-synthetic penicillin that is taken orally rather than by injection. His research covered not only penicillin, but also peptides, other antibiotics, alkaloids, and steroids. (en) John Clark Sheehan (Battle Creek, 23 settembre 1915 – Key Biscayne, 21 marzo 1992) è stato un chimico statunitense. PennicillinaV Docente al MIT dal 1952, nel 1958 sintetizzò la penicillina V. Si deve inoltre a lui la sintesi dell'ampicillina. (it) Джон Кларк Шихан (англ. John Clark Sheehan; 23 сентября 1915, Баттл-Крик, Мичиган, 21 марта 1992, Ки-Бискейн, Флорида) — американский химик-органик, первым открывший синтетический путь к пенициллину, сыгравшему огромную роль в медицине второй половины XX века. 6-аминопенициллановая кислота, полученная на промежуточной стадии синтеза пенициллина-V, легла в основу сотен новых антибиотиков пенициллинового ряда. Исследования Шихана также коснулись алкалоидов, стероидов, пептидных антибиотиков и др. (ru) |
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جون س. شيهان (بالإنجليزية: John C. Sheehan) هو أستاذ جامعي وكيميائي أمريكي، ولد في 23 سبتمبر 1915 في باتل كريك في الولايات المتحدة، وتوفي في 21 مارس 1992 في كي بيسكاين في الولايات المتحدة. (ar) John Clark Sheehan (* 23. September 1915; † 21. März 1992) war ein US-amerikanischer Chemiker und Professor für Organische Chemie am Massachusetts Institute of Technology (MIT). (de) John Clark Sheehan (Battle Creek, 23 settembre 1915 – Key Biscayne, 21 marzo 1992) è stato un chimico statunitense. PennicillinaV Docente al MIT dal 1952, nel 1958 sintetizzò la penicillina V. Si deve inoltre a lui la sintesi dell'ampicillina. (it) Джон Кларк Шихан (англ. John Clark Sheehan; 23 сентября 1915, Баттл-Крик, Мичиган, 21 марта 1992, Ки-Бискейн, Флорида) — американский химик-органик, первым открывший синтетический путь к пенициллину, сыгравшему огромную роль в медицине второй половины XX века. 6-аминопенициллановая кислота, полученная на промежуточной стадии синтеза пенициллина-V, легла в основу сотен новых антибиотиков пенициллинового ряда. Исследования Шихана также коснулись алкалоидов, стероидов, пептидных антибиотиков и др. (ru) John Clark Sheehan (September 23, 1915 – March 21, 1992) was an American organic chemist whose work on synthetic penicillin led to tailor-made forms of the drug. After nine years of hard work at the Massachusetts Institute of Technology (M.I.T.), he became the first to discover a practical method for synthesizing penicillin V. While achieving total synthesis, Sheehan also produced an intermediate compound, 6-aminopenicillanic acid, which turned out to be the foundation of hundreds of kinds of synthetic penicillin. Dr. Sheehan's research on synthetic penicillin paved the way for the development of customized forms of the lifesaving antibiotic that target specific bacteria. Over the four decades he worked at M.I.T., Sheehan came to hold over 30 patents, including the invention of ampicillin, (en) |
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جون س. شيهان (ar) John C. Sheehan (de) John C. Sheehan (en) John Sheehan (it) Шихан, Джон Кларк (ru) |
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