Kornblum–DeLaMare rearrangement (original) (raw)

The Kornblum–DeLaMare rearrangement is a rearrangement reaction in organic chemistry in which a primary or secondary organic peroxide is converted to the corresponding ketone and alcohol under acid or base catalysis. The reaction is relevant as a tool in organic synthesis and is a key step in the biosynthesis of prostaglandins. The base can be a hydroxide such as potassium hydroxide or an amine such as triethylamine.