| dbo:abstract |
Lefamulin ist ein antibiotisch wirksamer Arzneistoff aus der Gruppe der . In den USA ist es seit August 2019, in der EU seit Juli 2020 als Xenleta zur Behandlung ambulant erworbener Lungenentzündungen (Community-Acquired Bacterial Pneumonia, CABP) zugelassen. (de) Lefamulin, sold under the brand name Xenleta, is an antibiotic medication used it to treat adults with community-acquired bacterial pneumonia. It is taken by mouth or by injection into a vein. Relatively common side effects include diarrhea, nausea, pain at the site of injection, and liver inflammation. It is a pleuromutilin antibiotic that inhibits the large subunit of bacterial ribosomes. Lefamulin was approved for medical use in the United States in August 2019, and in the European Union in July 2020. (en) La léfamuline est un antibiotique de la famille des . (fr) Лефамулин — полусинтетический антибиотик класса плевромутилинов. Одобрен для применения: США(2019). (ru) |
| dbo:alternativeName |
Xenleta (en) |
| dbo:casNumber |
1061337-51-6 |
| dbo:chEMBL |
3291398 |
| dbo:drugbank |
DB12825 |
| dbo:fdaUniiCode |
21904A5386 |
| dbo:kegg |
D11631 |
| dbo:pubchem |
25185057 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Lefamulin_skeletal.svg?width=300 |
| dbo:wikiPageExternalLink |
https://druginfo.nlm.nih.gov/drugportal/name/lefamulin%7C |
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dbr:Enterococcus_faecium dbr:Methicillin-resistant_Staphylococcus_aureus dbr:Moraxella_catarrhalis dbr:Prokaryotic_large_ribosomal_subunit dbr:Antibiotic dbr:In_vitro dbc:Vinyl_compounds dbr:Oral_administration dbr:Pleuromutilin_antibiotic dbr:Food_and_Drug_Administration dbr:Fast_track_(FDA) dbr:Acute_bacterial_skin_and_skin-structure_infection dbr:Streptococcus_pneumoniae dbc:Pleuromutilin_antibiotics dbr:Pneumonia dbr:Ribosome dbr:Nabriva_Therapeutics dbr:Viridans_group_Streptococci |
| dbp:atcPrefix |
J01 (en) |
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XX12 (en) |
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28 (xsd:integer) |
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1061337 (xsd:integer) |
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3291398 (xsd:integer) |
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32701544 (xsd:integer) |
| dbp:dailymedid |
Lefamulin (en) |
| dbp:drugbank |
DB12825 (en) |
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45 (xsd:integer) |
| dbp:iupacName |
-3 (xsd:integer) |
| dbp:kegg |
D11631 (en) |
| dbp:legalCa |
Rx-only (en) |
| dbp:legalEu |
Rx-only (en) |
| dbp:legalUs |
Rx-only (en) |
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1 (xsd:integer) |
| dbp:o |
5 (xsd:integer) |
| dbp:pubchem |
25185057 (xsd:integer) |
| dbp:routesOfAdministration |
Intravenous, by mouth (en) |
| dbp:s |
1 (xsd:integer) |
| dbp:smiles |
C[C@@H]1CC[C@@]23CCC[C@H]2[C@@]1C (en) |
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1 (xsd:integer) |
| dbp:stdinchikey |
KPVIXBKIJXZQJX-FCEONZPQSA-N (en) |
| dbp:synonyms |
BC-3781 (en) |
| dbp:tradename |
Xenleta (en) |
| dbp:unii |
21904 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Antibiotic-stub dbt:Cite_web dbt:Infobox_drug dbt:Portal_bar dbt:Reflist dbt:Use_dmy_dates dbt:Drugs.com dbt:Protein_synthesis_inhibitor_antibiotics |
| dct:subject |
dbc:Vinyl_compounds dbc:Pleuromutilin_antibiotics |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
Lefamulin ist ein antibiotisch wirksamer Arzneistoff aus der Gruppe der . In den USA ist es seit August 2019, in der EU seit Juli 2020 als Xenleta zur Behandlung ambulant erworbener Lungenentzündungen (Community-Acquired Bacterial Pneumonia, CABP) zugelassen. (de) Lefamulin, sold under the brand name Xenleta, is an antibiotic medication used it to treat adults with community-acquired bacterial pneumonia. It is taken by mouth or by injection into a vein. Relatively common side effects include diarrhea, nausea, pain at the site of injection, and liver inflammation. It is a pleuromutilin antibiotic that inhibits the large subunit of bacterial ribosomes. Lefamulin was approved for medical use in the United States in August 2019, and in the European Union in July 2020. (en) La léfamuline est un antibiotique de la famille des . (fr) Лефамулин — полусинтетический антибиотик класса плевромутилинов. Одобрен для применения: США(2019). (ru) |
| rdfs:label |
Lefamulin (de) Léfamuline (fr) Lefamulin (en) Лефамулин (ru) |
| owl:sameAs |
yago-res:Lefamulin wikidata:Lefamulin dbpedia-de:Lefamulin dbpedia-fa:Lefamulin dbpedia-fi:Lefamulin dbpedia-fr:Lefamulin dbpedia-ro:Lefamulin dbpedia-ru:Lefamulin dbpedia-vi:Lefamulin https://global.dbpedia.org/id/2LoUL |
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wikipedia-en:Lefamulin?oldid=1118399524&ns=0 |
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wiki-commons:Special:FilePath/Lefamulin_skeletal.svg |
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wikipedia-en:Lefamulin |
| is dbo:wikiPageRedirects of |
dbr:Lefamulin_acetate dbr:Xenleta |
| is dbo:wikiPageWikiLink of |
dbr:Antibiotic dbr:ATC_code_J01 dbr:Bioprospecting dbr:Pleuromutilin dbr:Lefamulin_acetate dbr:Xenleta |
| is foaf:primaryTopic of |
wikipedia-en:Lefamulin |
