| dbo:abstract |
Liotrix is a 4:1 mixture of thyroxine (T4) and triiodothyronine (T3) made synthetically. It is used to replenish thyroid hormones in thyroid deficiency and hypothyroidism. The only brand of liotrix available in the U.S. is Thyrolar, manufactured by Forest Laboratories. In 2013, Forest Laboratories has released the following statement regarding the limited availability of liotrix: "U.S. Pharmacopeia, an official public standards-setting authority for prescription and over-the-counter medicines and other health care products manufactured or sold in the United States, has mandated new specifications for a component used in the manufacturing of Thyrolar. As a result, all strengths of Thyrolar are currently on long-term back order while modifications necessary to meet these new specifications are made." (en) |
| dbo:alternativeName |
Thyrolar (en) |
| dbo:casNumber |
8065-29-0 |
| dbo:drugbank |
DB01583 |
| dbo:fdaUniiCode |
YW8HJ0N26X |
| dbo:pubchem |
165686 |
| dbo:wikiPageID |
25725056 (xsd:integer) |
| dbo:wikiPageLength |
5415 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1058236018 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Irregular_heartbeat dbr:Hypothyroidism dbr:Patients dbc:Thyroid_hormone_receptor_agonists dbr:Thyroxine dbr:Chest_pain dbr:Overdose dbr:Congenital_hypothyroidism dbr:Triiodothyronine dbc:Hormones_of_the_thyroid_gland dbc:Thyroid dbr:Dyspnea dbr:Forest_Laboratories dbr:Diarrhea dbr:Differential_diagnosis dbr:Hashimoto's_thyroiditis dbr:Headache dbr:Hyperthyroidism dbc:Combination_drugs dbr:Sweating dbr:Titration dbr:Thyroid_cancer dbr:Euthyroid dbr:Goiter dbr:Obesity dbr:Thyroid_hormone dbr:Trembling dbr:Thyroid_stimulating_hormone dbr:Sympathomimetic_cardiovascular dbr:Thyroid_gland_autonomy |
| dbp:atcPrefix |
H03 (en) |
| dbp:atcSuffix |
AA03 (en) |
| dbp:casNumber |
8065 (xsd:integer) |
| dbp:chemspiderid |
none (en) |
| dbp:class |
dbr:Thyroid_hormone Thyroid hormone (en) |
| dbp:component |
Thyroxine (en) Triiodothyronine (en) |
| dbp:drugbank |
DB01583 (en) |
| dbp:legalUs |
Rx (en) |
| dbp:pregnancyUs |
A (en) |
| dbp:pubchem |
165686 (xsd:integer) |
| dbp:routesOfAdministration |
Oral (en) |
| dbp:tradename |
Thyrolar (en) |
| dbp:type |
combo (en) |
| dbp:unii |
YW8HJ0N26X (en) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Fdacite dbt:Thyroid_hormone_receptor_modulators dbt:Thyroid_therapy dbt:Drugs.com |
| dct:subject |
dbc:Thyroid_hormone_receptor_agonists dbc:Hormones_of_the_thyroid_gland dbc:Thyroid dbc:Combination_drugs |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:CombinationDrug yago:Abstraction100002137 yago:BodySubstance105263850 yago:Hormone105407119 yago:LiquidBodySubstance105397468 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 yago:WikicatHormonesOfTheThyroidGland dbo:Drug yago:Secretion105404728 yago:Substance100019613 |
| rdfs:comment |
Liotrix is a 4:1 mixture of thyroxine (T4) and triiodothyronine (T3) made synthetically. It is used to replenish thyroid hormones in thyroid deficiency and hypothyroidism. The only brand of liotrix available in the U.S. is Thyrolar, manufactured by Forest Laboratories. (en) |
| rdfs:label |
Liotrix (en) |
| owl:sameAs |
freebase:Liotrix yago-res:Liotrix wikidata:Liotrix dbpedia-sh:Liotrix dbpedia-sr:Liotrix dbpedia-vi:Liotrix https://global.dbpedia.org/id/4qWkG |
| prov:wasDerivedFrom |
wikipedia-en:Liotrix?oldid=1058236018&ns=0 |
| foaf:isPrimaryTopicOf |
wikipedia-en:Liotrix |
| is dbo:wikiPageRedirects of |
dbr:Thyrolar |
| is dbo:wikiPageWikiLink of |
dbr:Thyroid_hormones dbr:Forest_Laboratories dbr:Thyrolar |
| is foaf:primaryTopic of |
wikipedia-en:Liotrix |