Live single-cell imaging (original) (raw)

In systems biology, live single-cell imaging is a live cell imaging technique that combines traditional live cell imaging and time-lapse microscopy techniques with automated cell tracking and feature extraction, drawing many techniques from high-content screening. It is used to study signalling dynamics and behaviour in populations of individual living cells. Live single cell studies can reveal key behaviours that would otherwise be masked in population averaging experiments such as western blots.