Lofendazam (original) (raw)
Lofendazam is an organic molecule which is a benzodiazepine derivative. Lofendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring; therefore, lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam. Lofendazam as a human pharmaceutical has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives. It is an active metabolite of another benzodiazepine, arfendazam.
| Property | Value |
|---|---|
| dbo:abstract | Lofendazam is an organic molecule which is a benzodiazepine derivative. Lofendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring; therefore, lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam. Lofendazam as a human pharmaceutical has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives. It is an active metabolite of another benzodiazepine, arfendazam. (en) Il lofendazam è uno psicofarmaco appartenente alla categoria delle benzodiazepine. Il Lofendazam è una 1,5-benzodiazepina, con gli atomi di azoto situati nelle posizioni 1 e 5 dell'anello diazepinico; pertanto, il lofendazam è più strettamente correlato ad altre 1,5-benzodiazepine come il clobazam. Il lofendazam come farmaco umano ha effetti sedativi e ansiolitici simili a quelli prodotti da altri derivati delle benzodiazepine. È un metabolita attivo di un'altra benzodiazepina, l'arfendazam. (it) |
| dbo:casNumber | 29176-29-2 |
| dbo:fdaUniiCode | V7O53S50SN |
| dbo:pubchem | 71709 |
| dbo:thumbnail | wiki-commons:Special:FilePath/Lofendazam.svg?width=300 |
| dbo:wikiPageID | 13397257 (xsd:integer) |
| dbo:wikiPageLength | 2938 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1093940227 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Nitrogen dbr:Metabolite dbr:Benzodiazepine dbc:Chloroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Lactams dbr:Clobazam dbr:Anxiolytic dbr:Diazepine dbc:Benzodiazepines dbr:Arfendazam dbr:Sedative |
| dbp:atcPrefix | none (en) |
| dbp:c | 15 (xsd:integer) |
| dbp:casNumber | 29176 (xsd:integer) |
| dbp:chemspiderid | 64759 (xsd:integer) |
| dbp:cl | 1 (xsd:integer) |
| dbp:h | 13 (xsd:integer) |
| dbp:iupacName | 8 (xsd:integer) |
| dbp:molecularWeight | 272.730000 (xsd:double) |
| dbp:n | 2 (xsd:integer) |
| dbp:o | 1 (xsd:integer) |
| dbp:pubchem | 71709 (xsd:integer) |
| dbp:smiles | Clc3ccc1cc3 (en) |
| dbp:stdinchi | 1 (xsd:integer) |
| dbp:stdinchikey | IUJQOUHDFKALCY-UHFFFAOYSA-N (en) |
| dbp:unii | V7O53S50SN (en) |
| dbp:verifiedrevid | 447931436 (xsd:integer) |
| dbp:width | 180 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Drugbox dbt:GABAAR_PAMs dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Fdacite dbt:Stdinchicite dbt:Benzodiazepines |
| dcterms:subject | dbc:Chloroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Lactams dbc:Benzodiazepines |
| gold:hypernym | dbr:Molecule |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatBenzodiazepines yago:Agent114778436 yago:Benzodiazepine102830852 yago:CausalAgent100007347 yago:Drug103247620 yago:DrugOfAbuse103248958 yago:Matter100020827 yago:Medicine103740161 yago:MinorTranquilizer103771443 yago:MuscleRelaxant103800001 yago:PhysicalEntity100001930 yago:PsychotropicAgent104017429 yago:Relaxant104072811 dbo:ChemicalCompound dbo:Drug yago:Sedative-hypnotic104166841 yago:Sedative104166553 yago:Substance100020090 yago:Tranquilizer104470232 umbel-rc:DrugProduct |
| rdfs:comment | Lofendazam is an organic molecule which is a benzodiazepine derivative. Lofendazam is a 1,5-benzodiazepine, with the nitrogen atoms located at positions 1 and 5 of the diazepine ring; therefore, lofendazam is most closely related to other 1,5-benzodiazepines such as clobazam. Lofendazam as a human pharmaceutical has sedative and anxiolytic effects similar to those produced by other benzodiazepine derivatives. It is an active metabolite of another benzodiazepine, arfendazam. (en) Il lofendazam è uno psicofarmaco appartenente alla categoria delle benzodiazepine. Il Lofendazam è una 1,5-benzodiazepina, con gli atomi di azoto situati nelle posizioni 1 e 5 dell'anello diazepinico; pertanto, il lofendazam è più strettamente correlato ad altre 1,5-benzodiazepine come il clobazam. Il lofendazam come farmaco umano ha effetti sedativi e ansiolitici simili a quelli prodotti da altri derivati delle benzodiazepine. È un metabolita attivo di un'altra benzodiazepina, l'arfendazam. (it) |
| rdfs:label | Lofendazam (it) Lofendazam (en) |
| owl:sameAs | freebase:Lofendazam yago-res:Lofendazam wikidata:Lofendazam dbpedia-it:Lofendazam dbpedia-sh:Lofendazam dbpedia-sr:Lofendazam dbpedia-vi:Lofendazam https://global.dbpedia.org/id/4r57S |
| prov:wasDerivedFrom | wikipedia-en:Lofendazam?oldid=1093940227&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Lofendazam.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Lofendazam |
| is dbo:wikiPageWikiLink of | dbr:List_of_benzodiazepines dbr:Clobazam dbr:Arfendazam dbr:List_of_drugs:_Lo |
| is foaf:primaryTopic of | wikipedia-en:Lofendazam |
