| dbo:abstract |
ML-SI3 es un compuesto químico que actúa como "antagonista" (es decir, bloqueador de canales) de la familia TRPML de canales de calcio, con mayor actividad en el canal TRPML1, aunque también bloquea los canales relacionados TRPML2 y TRPML3 con menor afinidad. Se utiliza para investigar el papel de TRPML1 y sus diversas funciones en los lisosomas y en otras partes del cuerpo. (es) ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel blocker) of the TRPML family of calcium channels, with greatest activity at the TRPML1 channel, although it also blocks the related TRPML2 and TRPML3 channels with lower affinity. It is used for research into the role of TRPML1 and its various functions in lysosomes and elsewhere in the body. (en) |
| dbo:casNumber |
891016-02-7 |
| dbo:pubchem |
94784693 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/ML-SI3_structure.png?width=300 |
| dbo:wikiPageID |
65843198 (xsd:integer) |
| dbo:wikiPageLength |
4348 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1064824012 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:TRPML dbc:Phenylpiperazines dbr:MK6-83 dbc:Sulfonamides dbr:Lysosome dbr:TRPML1 dbr:TRPML2 dbr:TRPML3 |
| dbp:c |
23 (xsd:integer) |
| dbp:casNumber |
891016 (xsd:integer) |
| dbp:chemspiderid |
20304221 (xsd:integer) |
| dbp:h |
31 (xsd:integer) |
| dbp:iupacName |
N-[-2-[4-piperazin-1-yl]cyclohexyl]benzenesulfonamide (en) |
| dbp:n |
3 (xsd:integer) |
| dbp:o |
3 (xsd:integer) |
| dbp:pubchem |
94784693 (xsd:integer) |
| dbp:s |
1 (xsd:integer) |
| dbp:smiles |
COC1=CC=CC=C1N2CCN[C@H]3CCCC[C@@H]3NSC4=CC=CC=C4 (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
OVTXOMMQHRIKGL-SFTDATJTSA-N (en) |
| dbp:width |
220 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Reflist dbt:Transient_receptor_potential_channel_modulators |
| dcterms:subject |
dbc:Phenylpiperazines dbc:Sulfonamides |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
ML-SI3 es un compuesto químico que actúa como "antagonista" (es decir, bloqueador de canales) de la familia TRPML de canales de calcio, con mayor actividad en el canal TRPML1, aunque también bloquea los canales relacionados TRPML2 y TRPML3 con menor afinidad. Se utiliza para investigar el papel de TRPML1 y sus diversas funciones en los lisosomas y en otras partes del cuerpo. (es) ML-SI3 is a chemical compound which acts as an "antagonist" (i.e. channel blocker) of the TRPML family of calcium channels, with greatest activity at the TRPML1 channel, although it also blocks the related TRPML2 and TRPML3 channels with lower affinity. It is used for research into the role of TRPML1 and its various functions in lysosomes and elsewhere in the body. (en) |
| rdfs:label |
ML-SI3 (es) ML-SI3 (en) |
| owl:sameAs |
wikidata:ML-SI3 dbpedia-es:ML-SI3 https://global.dbpedia.org/id/FT41W |
| prov:wasDerivedFrom |
wikipedia-en:ML-SI3?oldid=1064824012&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/ML-SI3_structure.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:ML-SI3 |
| is dbo:wikiPageWikiLink of |
dbr:MK6-83 |
| is foaf:primaryTopic of |
wikipedia-en:ML-SI3 |
