Macroovalocyte (original) (raw)
Macroovalocytes are enlarged, oval-shaped erythrocytes (red blood cells). They are not seen in healthy blood, and are most commonly seen in megaloblastic anemia. In most instances, the macroovalocyte morphology is due to megaloblastic erythropoiesis (Vitamin B-12 or folate deficiency) but may be seen with dyserythropoiesis. Although macroovalocytes are characteristic in these deficiency states, they are not pathognomonic. Poikilocytosis is often present, particularly in more advanced cases. If associated with hypersegmented granulocytes in the absence of other causes (e.g. drugs), the findings are essentially diagnostic of Vitamin B-12 or folate deficiency.
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| dbo:abstract | Macroovalocytes are enlarged, oval-shaped erythrocytes (red blood cells). They are not seen in healthy blood, and are most commonly seen in megaloblastic anemia. In most instances, the macroovalocyte morphology is due to megaloblastic erythropoiesis (Vitamin B-12 or folate deficiency) but may be seen with dyserythropoiesis. Although macroovalocytes are characteristic in these deficiency states, they are not pathognomonic. Poikilocytosis is often present, particularly in more advanced cases. If associated with hypersegmented granulocytes in the absence of other causes (e.g. drugs), the findings are essentially diagnostic of Vitamin B-12 or folate deficiency. (en) |
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| dbo:wikiPageWikiLink | dbc:Blood_cells dbr:Dyserythropoiesis dbr:Megaloblastic_anemia dbr:Poikilocytosis dbr:Folate dbr:Vitamin_B-12 dbr:Erythrocytes |
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| dcterms:subject | dbc:Blood_cells |
| gold:hypernym | dbr:Erythrocytes |
| rdf:type | yago:WikicatBloodCells yago:BloodCell105449268 yago:Cell100006484 yago:LivingThing100004258 yago:Object100002684 yago:PhysicalEntity100001930 yago:SomaticCell105430628 yago:Whole100003553 |
| rdfs:comment | Macroovalocytes are enlarged, oval-shaped erythrocytes (red blood cells). They are not seen in healthy blood, and are most commonly seen in megaloblastic anemia. In most instances, the macroovalocyte morphology is due to megaloblastic erythropoiesis (Vitamin B-12 or folate deficiency) but may be seen with dyserythropoiesis. Although macroovalocytes are characteristic in these deficiency states, they are not pathognomonic. Poikilocytosis is often present, particularly in more advanced cases. If associated with hypersegmented granulocytes in the absence of other causes (e.g. drugs), the findings are essentially diagnostic of Vitamin B-12 or folate deficiency. (en) |
| rdfs:label | Macroovalocyte (en) |
| owl:sameAs | freebase:Macroovalocyte yago-res:Macroovalocyte wikidata:Macroovalocyte https://global.dbpedia.org/id/4qcmr |
| prov:wasDerivedFrom | wikipedia-en:Macroovalocyte?oldid=1105851722&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Macroovalocyte |
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