Mal regulon (original) (raw)
In bacterial genetics, the mal regulon is a regulon - or group of genes under common regulation - associated with the catabolism of maltose and maltodextrins. The system is especially well characterized in the model organism Escherichia coli, where it is classically described as a group of ten genes in multiple operons whose expression is regulated by a single regulatory protein, . MalT binds to maltose or maltodextrin and undergoes a conformational change that allows it to bind DNA at sequences near the promoters of genes required for uptake and catabolism of these sugars. The maltose regulation system in E. coli is a classic example of positive regulation. malT is regulated by catabolite repression via the catabolite activator protein. Genes under the control of malT include ATP-binding
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| dbo:abstract | In bacterial genetics, the mal regulon is a regulon - or group of genes under common regulation - associated with the catabolism of maltose and maltodextrins. The system is especially well characterized in the model organism Escherichia coli, where it is classically described as a group of ten genes in multiple operons whose expression is regulated by a single regulatory protein, . MalT binds to maltose or maltodextrin and undergoes a conformational change that allows it to bind DNA at sequences near the promoters of genes required for uptake and catabolism of these sugars. The maltose regulation system in E. coli is a classic example of positive regulation. malT is regulated by catabolite repression via the catabolite activator protein. Genes under the control of malT include ATP-binding cassette transporter components, maltoporin, maltose binding protein, and several enzymes. Other Gram-negative bacteria such as Klebsiella pneumoniae have additional genes under the control of malT. In many Gram-positive bacteria, such as Streptococcus pneumoniae, maltose catabolism is regulated differently, via a transcriptional repressor called malR, in the lac repressor family. (en) |
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| dbo:wikiPageWikiLink | dbr:DNA dbr:Gene_expression dbr:Genetics dbr:Enzyme dbr:Gene dbr:Gene_regulation dbr:Conformational_change dbr:Lac_repressor dbr:Operon dbr:Maltodextrin dbr:Maltoporin dbr:Maltose dbr:Regulon dbr:Bacteria dbr:Gram-negative dbr:Gram-positive dbr:ATP-binding_cassette_transporter dbc:Molecular_biology dbr:Escherichia_coli dbr:Promoter_(genetics) dbc:Bacterial_genetics dbr:Streptococcus_pneumoniae dbr:Model_organism dbr:Catabolism dbr:Catabolite_activator_protein dbr:Catabolite_repression dbr:Klebsiella_pneumoniae dbr:Repressor dbr:Gene_transcription dbr:Regulatory_protein dbr:Maltose_binding_protein dbr:Positive_regulation dbr:MalT |
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| dcterms:subject | dbc:Molecular_biology dbc:Bacterial_genetics |
| rdfs:comment | In bacterial genetics, the mal regulon is a regulon - or group of genes under common regulation - associated with the catabolism of maltose and maltodextrins. The system is especially well characterized in the model organism Escherichia coli, where it is classically described as a group of ten genes in multiple operons whose expression is regulated by a single regulatory protein, . MalT binds to maltose or maltodextrin and undergoes a conformational change that allows it to bind DNA at sequences near the promoters of genes required for uptake and catabolism of these sugars. The maltose regulation system in E. coli is a classic example of positive regulation. malT is regulated by catabolite repression via the catabolite activator protein. Genes under the control of malT include ATP-binding (en) |
| rdfs:label | Mal regulon (en) |
| owl:sameAs | wikidata:Mal regulon https://global.dbpedia.org/id/hc4y |
| prov:wasDerivedFrom | wikipedia-en:Mal_regulon?oldid=1015142751&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Mal_regulon |
| is dbo:wikiPageRedirects of | dbr:MaI_regulon dbr:Maltose_regulon |
| is dbo:wikiPageWikiLink of | dbr:Maltose-binding_protein dbr:MaI_regulon dbr:Catabolite_activator_protein dbr:Maltose_regulon |
| is foaf:primaryTopic of | wikipedia-en:Mal_regulon |