Mean platelet volume (original) (raw)
Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests as part of the CBC. Since the average platelet size is larger when the body is producing increased numbers of platelets, the MPV test results can be used to make inferences about platelet production in bone marrow or platelet destruction problems. An increased mean platelet volume (MPV) increases the risk to suffer a heart disease
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| dbo:abstract | Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests as part of the CBC. Since the average platelet size is larger when the body is producing increased numbers of platelets, the MPV test results can be used to make inferences about platelet production in bone marrow or platelet destruction problems. An increased mean platelet volume (MPV) increases the risk to suffer a heart disease MPV may be higher when there is destruction of platelets. This may be seen in immune thrombocytopenic purpura (ITP), myeloproliferative diseases and Bernard–Soulier syndrome. It may also be related to pre-eclampsia and recovery from transient hypoplasia. Abnormally low MPV values may correlate with thrombocytopenia when it is due to impaired production of megakaryocytes in the bone marrow, such as in aplastic anemia. A low MPV may indicate inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis. A high MPV is also a bad prognostic marker in patients with sepsis or septic shock. In addition, low MPV may correlate with abnormally small platelet size, sometimes a symptom of a spectrum referred to as Wiskott–Aldrich syndrome (WAS), caused by a genetic mutation of the WAS gene. Sample for MPV testing is obtained in a Lavender-Top EDTA tube. A typical range of platelet volumes is 9.4–12.3 fL (femtolitre), equivalent to spheres 2.65 to 2.9 µm in diameter. (en) Le volume plaquettaire moyen (VPM) est une mesure calculée par une machine, qui évalue la taille moyenne des plaquettes présentes dans le sang. Il est le plus souvent inclus dans les tests sanguins dans le cadre du CBC. La taille moyenne des plaquettes est plus grande lorsque le corps produit de plus en plus de plaquettes, les résultats du test VPM sont utilisés pour tirer des conclusions sur la production de plaquettes en cas de problèmes de destruction de la moelle osseuse ou de plaquettes. Le VPM est plus important (supérieur à 10,9) s'il y a destruction des plaquettes. Cela peut être observé dans les maladies inflammatoires de l'intestin, le purpura thrombopénique immunologique (PTI), les maladies myéloprolifératives et le syndrome de Bernard-Soulier . Il peut aussi être lié à la pré-éclampsie et au rétablissement d'une hypoplasie transitoire. Des valeurs de volume plaquettaire moyen, anormalement basses (inférieures à 7.5) sont en corrélation avec une thrombocytopénie un VPM bas peut être corrélé à une taille de plaquette trop petite, parfois le symptôme d'un spectre appelé syndrome de Wiskott-Aldrich (WAS) causé par une mutation génétique du gène WAS. Un échantillon pour le test VPM s'obstient dans un tube EDTA Lavender-Top. Une gamme typique de volumes de plaquettes est comprise entre 9,4 et 12,3. fL (femtolitre), équivalent aux sphères 2,65 à 2,9 µm de diamètre. (fr) |
| dbo:wikiPageExternalLink | https://www.mrlabtest.com/high-MPV-blood.htm http://www.omim.org/entry/188000 https://books.google.com/books%3Fid=yF5WQdAcdfcC&pg=PA974&dq=atrus+syndrome&hl=en&sa=X&ved=0ahUKEwj258T4orrZAhWunOAKHblrB1UQ6AEINDAC%23v=onepage&q=atrus%20syndrome&f=false http://www.medicinenet.com/thrombocytopenia_low_platelet_count/page4.htm |
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| dbp:name | Mean platelet volume (en) |
| dbp:purpose | can be used to make inferences about platelet production in bone marrow or platelet destruction problems (en) |
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| rdfs:comment | Mean platelet volume (MPV) is a machine-calculated measurement of the average size of platelets found in blood and is typically included in blood tests as part of the CBC. Since the average platelet size is larger when the body is producing increased numbers of platelets, the MPV test results can be used to make inferences about platelet production in bone marrow or platelet destruction problems. An increased mean platelet volume (MPV) increases the risk to suffer a heart disease (en) Le volume plaquettaire moyen (VPM) est une mesure calculée par une machine, qui évalue la taille moyenne des plaquettes présentes dans le sang. Il est le plus souvent inclus dans les tests sanguins dans le cadre du CBC. La taille moyenne des plaquettes est plus grande lorsque le corps produit de plus en plus de plaquettes, les résultats du test VPM sont utilisés pour tirer des conclusions sur la production de plaquettes en cas de problèmes de destruction de la moelle osseuse ou de plaquettes. (fr) |
| rdfs:label | Volume plaquettaire moyen (fr) Mean platelet volume (en) |
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