Methylenediurea deaminase (original) (raw)

Methylenediurea deaminase (EC 3.5.3.21, methylenediurease) is an enzyme with systematic name methylenediurea aminohydrolase found in Brucella anthropi, a bacterium. This enzyme catalyses the following chemical reaction: methylenediurea + 2 H2O N-(hydroxymethyl)urea + 2 NH3 + CO2 (overall reaction)(1a) methylenediurea + H2O N-(carboxyaminomethyl)urea + NH3(1b) N-(carboxyaminomethyl)urea N-(aminomethyl)urea + CO2 (spontaneous)(1c) N-(aminomethyl)urea + H2O N-(hydroxymethyl)urea + NH3 (spontaneous) Methylenediurea is hydrolysed and decarboxylated to give an aminated methylurea.