Methylglyoxal reductase (NADPH-dependent) (original) (raw)
In enzymology, a methylglyoxal reductase (NADPH-dependent) (EC 1.1.1.283) is an enzyme that catalyzes the chemical reaction lactaldehyde + NADP+ methylglyoxal + NADPH + H+ Thus, the two substrates of this enzyme are lactaldehyde and NADP+, whereas its 3 products are methylglyoxal, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is lactaldehyde:NADP+ oxidoreductase. Other names in common use include lactaldehyde dehydrogenase (NADP+), and Gre2.
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| dbo:abstract | In enzymology, a methylglyoxal reductase (NADPH-dependent) (EC 1.1.1.283) is an enzyme that catalyzes the chemical reaction lactaldehyde + NADP+ methylglyoxal + NADPH + H+ Thus, the two substrates of this enzyme are lactaldehyde and NADP+, whereas its 3 products are methylglyoxal, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is lactaldehyde:NADP+ oxidoreductase. Other names in common use include lactaldehyde dehydrogenase (NADP+), and Gre2. (en) La méthylglyoxal réductase NADPH-dépendante est une oxydoréductase qui catalyse la réaction : (S)-lactaldéhyde + NADP+ méthylglyoxal + NADPH + H+. Cette enzyme intervient dans la (en). Présente chez des procaryotes telles que les levures, elle diffère de la méthylglyoxal réductase NADH-dépendante des mammifères par l'utilisation de NADP+ plutôt que de NAD+. Elle oxyde également le et le glyoxal. Chez E. coli, la réaction n'a été démontrée que dans le sens de l'oxydation. (fr) メチルグリオキサールレダクターゼ (NADPH依存)（メチルグリオキサールレダクターゼ (NADPHいそん)、methylglyoxal reductase (NADPH-dependent)）は、次の化学反応を触媒する酸化還元酵素である。 (S)-ラクトアルデヒド + NADP+ メチルグリオキサール + NADPH + H+ 反応式の通り、この酵素の基質は(S)-ラクトアルデヒドとNADP+、生成物はメチルグリオキサールとNADPHとH+である。 組織名は(S)-lactaldehyde:NADP+ oxidoreductaseで、別名にmethylglyoxal reductase, D-lactaldehyde dehydrogenaseがある。 (ja) La metilgliossale reduttasi (NADPH-dipendente) è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: + NADP+ ⇄ metilgliossale + NADPH + H+ Questo enzima del lievito Saccharomyces cerevisiae catalizza la conversione del metilgliossale in lattaldeide; non è stata dimostrata la reazione inversa. Differisce nel tipo di coenzima necessario, dalla metilgliossale reduttasi (dipendente da NAD), che si trova nei mammiferi. Agisce anche sui e gliossali. (it) |
| dbo:ecNumber | 1.1.1.283 |
| dbo:wikiPageID | 13901228 (xsd:integer) |
| dbo:wikiPageLength | 2177 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 997928410 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:List_of_enzymes dbr:Enzymology dbc:EC_1.1.1 dbc:Enzymes_of_unknown_structure dbc:NADPH-dependent_enzymes dbr:Chemical_reaction dbr:Enzyme dbr:Substrate_(biochemistry) dbr:Nicotinamide_adenine_dinucleotide_phosphate dbr:Product_(chemistry) dbr:Hydrogen_ion dbr:Lactaldehyde dbr:Methylglyoxal dbr:Catalysis dbr:Oxidoreductase |
| dbp:ecNumber | 1.100000 (xsd:double) |
| dbp:goCode | 43892 (xsd:integer) |
| dbp:iubmbEcNumber | 1 (xsd:integer) |
| dbp:name | methylglyoxal reductase (en) |
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| dct:subject | dbc:EC_1.1.1 dbc:Enzymes_of_unknown_structure dbc:NADPH-dependent_enzymes |
| rdf:type | owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:WikicatNADPH-dependentEnzymes yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymesOfUnknownStructure |
| rdfs:comment | In enzymology, a methylglyoxal reductase (NADPH-dependent) (EC 1.1.1.283) is an enzyme that catalyzes the chemical reaction lactaldehyde + NADP+ methylglyoxal + NADPH + H+ Thus, the two substrates of this enzyme are lactaldehyde and NADP+, whereas its 3 products are methylglyoxal, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is lactaldehyde:NADP+ oxidoreductase. Other names in common use include lactaldehyde dehydrogenase (NADP+), and Gre2. (en) La méthylglyoxal réductase NADPH-dépendante est une oxydoréductase qui catalyse la réaction : (S)-lactaldéhyde + NADP+ méthylglyoxal + NADPH + H+. Cette enzyme intervient dans la (en). Présente chez des procaryotes telles que les levures, elle diffère de la méthylglyoxal réductase NADH-dépendante des mammifères par l'utilisation de NADP+ plutôt que de NAD+. Elle oxyde également le et le glyoxal. Chez E. coli, la réaction n'a été démontrée que dans le sens de l'oxydation. (fr) メチルグリオキサールレダクターゼ (NADPH依存)（メチルグリオキサールレダクターゼ (NADPHいそん)、methylglyoxal reductase (NADPH-dependent)）は、次の化学反応を触媒する酸化還元酵素である。 (S)-ラクトアルデヒド + NADP+ メチルグリオキサール + NADPH + H+ 反応式の通り、この酵素の基質は(S)-ラクトアルデヒドとNADP+、生成物はメチルグリオキサールとNADPHとH+である。 組織名は(S)-lactaldehyde:NADP+ oxidoreductaseで、別名にmethylglyoxal reductase, D-lactaldehyde dehydrogenaseがある。 (ja) La metilgliossale reduttasi (NADPH-dipendente) è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: + NADP+ ⇄ metilgliossale + NADPH + H+ Questo enzima del lievito Saccharomyces cerevisiae catalizza la conversione del metilgliossale in lattaldeide; non è stata dimostrata la reazione inversa. Differisce nel tipo di coenzima necessario, dalla metilgliossale reduttasi (dipendente da NAD), che si trova nei mammiferi. Agisce anche sui e gliossali. (it) |
| rdfs:label | Méthylglyoxal réductase NADPH-dépendante (fr) Metilgliossale reduttasi (NADPH-dipendente) (it) Methylglyoxal reductase (NADPH-dependent) (en) メチルグリオキサールレダクターゼ (NADPH依存) (ja) |
| owl:sameAs | freebase:Methylglyoxal reductase (NADPH-dependent) yago-res:Methylglyoxal reductase (NADPH-dependent) wikidata:Methylglyoxal reductase (NADPH-dependent) dbpedia-fr:Methylglyoxal reductase (NADPH-dependent) dbpedia-it:Methylglyoxal reductase (NADPH-dependent) dbpedia-ja:Methylglyoxal reductase (NADPH-dependent) dbpedia-sh:Methylglyoxal reductase (NADPH-dependent) dbpedia-sr:Methylglyoxal reductase (NADPH-dependent) https://global.dbpedia.org/id/2WnYi |
| prov:wasDerivedFrom | wikipedia-en:Methylglyoxal_reductase_(NADPH-dependent)?oldid=997928410&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Methylglyoxal_reductase_(NADPH-dependent) |
| foaf:name | methylglyoxal reductase (NADPH-dependent) (en) |
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