Mezlocillin (original) (raw)
| Property | Value |
|---|---|
| dbo:abstract | ميزلوسيللين (بالإنجليزية: Mezlocillin) مضاد حيوي من زمرة البنسلينات. في الولايات المتحدة، يستعمل كعامل من عوامل الوقاية الجراحية وكذلك عدوى المسالك البولية. (ar) Mezlocillin ist eine organisch-chemische Verbindung aus der Gruppe der β-Lactam-Antibiotika, genauer der Ureidopenicilline (Acylaminopenicilline). Es wurde 1974 von der Bayer AG patentiert. Das Breitsprektrum-Antibiotikum wird in Form des Natriumsalz-Monohydrats eingesetzt. Das große Wirkungsspektrum ermöglicht, dass es sowohl gegen Gram-negative als auch gegen einige Gram-positive Bakterien wirkt. Das Medikament ist beispielsweise für eine Behandlung einer Infektion des Gallentrakts geeignet ist. (de) La mezlocilina es un antibiótico de la familia de las ureidopenicilinas. Su acción es similar a la azlocilina. (es) Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. (en) La mezlocilline est une molécule antibiotique, de la famille des pénicillines. (fr) La mezlocillina è un antibiotico penicillinico ad ampio spettro, attivo nei confronti dei batteri Gram-negativi e di alcuni Gram-positivi. A differenza della maggior parte delle penicilline ad ampio spettro questa viene escreta per via epatica, rendendola utile nel contrastare infezioni del tratto biliare. (it) |
| dbo:casNumber | 51481-65-3 |
| dbo:chEBI | 6919 |
| dbo:chEMBL | 1731 |
| dbo:drugbank | DB00948 |
| dbo:fdaUniiCode | OH2O403D1G |
| dbo:kegg | D05021 |
| dbo:pubchem | 656511 |
| dbo:thumbnail | wiki-commons:Special:FilePath/Mezlocillin.svg?width=300 |
| dbo:wikiPageExternalLink | http://www.wheelessonline.com/ortho/mezlocillin_mezlin |
| dbo:wikiPageID | 6049638 (xsd:integer) |
| dbo:wikiPageLength | 5500 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 982369241 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Pseudomonas dbr:Enterococcus_faecalis dbr:Morganella_morganii dbc:Penicillins dbr:Antibiotic dbr:Penicillin dbr:Penicillin_binding_proteins dbr:Intramuscular_injection dbr:Intravenous_therapy dbr:Proteus_mirabilis dbr:Proteus_vulgaris dbr:Providencia_rettgeri dbc:Imidazolidinones dbr:Pseudomonas_aeruginosa dbr:Enterobacter dbr:Liver dbr:Haemophilus_influenzae dbr:Azlocillin dbr:Bacteria dbc:Enantiopure_drugs dbr:Gram-negative dbr:Gram-positive dbr:Ampicillin dbr:Escherichia_coli dbr:Ethylenediamine dbr:Cell_wall dbr:Bacteroides dbr:Bacteroides_fragilis dbr:Kidney dbr:Methanesulfonyl_chloride dbr:Klebsiella dbr:Lysis dbr:Serratia_marcescens dbr:Neisseria_gonorrhoeae dbr:Peptococcus dbr:Peptostreptococcus dbr:Beta-lactam_antibiotic dbr:(2''R'')-2-[(3-methylsulfonyl...o[3.2.0]heptane-2- carboxylic_acid dbr:File:Mezlocillin_synthesis.svg |
| dbp:atcPrefix | J01 (en) |
| dbp:atcSuffix | CA10 (en) |
| dbp:c | 21 (xsd:integer) |
| dbp:casNumber | 51481 (xsd:integer) |
| dbp:chebi | 6919 (xsd:integer) |
| dbp:chembl | 1731 (xsd:integer) |
| dbp:chemspiderid | 570894 (xsd:integer) |
| dbp:drugbank | DB00948 (en) |
| dbp:eliminationHalfLife | -15840.0 |
| dbp:excretion | Renal and biliary (en) |
| dbp:h | 25 (xsd:integer) |
| dbp:iupacName | -33 (xsd:integer) |
| dbp:kegg | D05021 (en) |
| dbp:metabolism | dbr:Liver |
| dbp:n | 5 (xsd:integer) |
| dbp:o | 8 (xsd:integer) |
| dbp:pregnancyCategory | B (en) |
| dbp:proteinBound | 16 (xsd:integer) |
| dbp:pubchem | 656511 (xsd:integer) |
| dbp:routesOfAdministration | dbr:Intramuscular_injection dbr:Intravenous_therapy |
| dbp:s | 2 (xsd:integer) |
| dbp:smiles | O=C[C@@H]3N4C[C@@H][C@H]4SC3C (en) |
| dbp:stdinchi | 1 (xsd:integer) |
| dbp:stdinchikey | YPBATNHYBCGSSN-VWPFQQQWSA-N (en) |
| dbp:unii | OH2O403D1G (en) |
| dbp:verifiedrevid | 462252118 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Antibiotic-stub dbt:Cite_journal dbt:Div_col dbt:Div_col_end dbt:Drugbox dbt:Main dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Drugs.com dbt:DiseasesDB dbt:PenicillinAntiBiotics |
| dcterms:subject | dbc:Penicillins dbc:Imidazolidinones dbc:Enantiopure_drugs |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAntibiotics yago:WikicatBeta-lactamAntibiotics yago:WikicatMolecularFormulas yago:Abstraction100002137 yago:Agent114778436 yago:Antibacterial102716205 yago:Antibiotic102716866 yago:CausalAgent100007347 yago:Communication100033020 yago:Drug103247620 yago:Formula106816935 yago:Matter100020827 yago:Medicine103740161 yago:Message106598915 yago:MolecularFormula106817173 yago:PhysicalEntity100001930 dbo:Drug yago:Statement106722453 yago:Substance100020090 yago:WikicatEnantiopureDrugs umbel-rc:DrugProduct |
| rdfs:comment | ميزلوسيللين (بالإنجليزية: Mezlocillin) مضاد حيوي من زمرة البنسلينات. في الولايات المتحدة، يستعمل كعامل من عوامل الوقاية الجراحية وكذلك عدوى المسالك البولية. (ar) Mezlocillin ist eine organisch-chemische Verbindung aus der Gruppe der β-Lactam-Antibiotika, genauer der Ureidopenicilline (Acylaminopenicilline). Es wurde 1974 von der Bayer AG patentiert. Das Breitsprektrum-Antibiotikum wird in Form des Natriumsalz-Monohydrats eingesetzt. Das große Wirkungsspektrum ermöglicht, dass es sowohl gegen Gram-negative als auch gegen einige Gram-positive Bakterien wirkt. Das Medikament ist beispielsweise für eine Behandlung einer Infektion des Gallentrakts geeignet ist. (de) La mezlocilina es un antibiótico de la familia de las ureidopenicilinas. Su acción es similar a la azlocilina. (es) Mezlocillin is a broad-spectrum penicillin antibiotic. It is active against both Gram-negative and some Gram-positive bacteria. Unlike most other extended spectrum penicillins, it is excreted by the liver, therefore it is useful for biliary tract infections, such as ascending cholangitis. (en) La mezlocilline est une molécule antibiotique, de la famille des pénicillines. (fr) La mezlocillina è un antibiotico penicillinico ad ampio spettro, attivo nei confronti dei batteri Gram-negativi e di alcuni Gram-positivi. A differenza della maggior parte delle penicilline ad ampio spettro questa viene escreta per via epatica, rendendola utile nel contrastare infezioni del tratto biliare. (it) |
| rdfs:label | ميزلوسيللين (ar) Mezlocillin (de) Mezlocilina (es) Mezlocilline (fr) Mezlocillina (it) Mezlocillin (en) |
| owl:sameAs | freebase:Mezlocillin yago-res:Mezlocillin http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB00948 wikidata:Mezlocillin dbpedia-ar:Mezlocillin dbpedia-cy:Mezlocillin dbpedia-de:Mezlocillin dbpedia-es:Mezlocillin dbpedia-fa:Mezlocillin dbpedia-fi:Mezlocillin dbpedia-fr:Mezlocillin dbpedia-it:Mezlocillin dbpedia-ro:Mezlocillin dbpedia-sh:Mezlocillin dbpedia-sr:Mezlocillin dbpedia-th:Mezlocillin https://global.dbpedia.org/id/349tt |
| prov:wasDerivedFrom | wikipedia-en:Mezlocillin?oldid=982369241&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Mezlocillin.svg wiki-commons:Special:FilePath/Mezlocillin_synthesis.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Mezlocillin |
| is dbo:wikiPageRedirects of | dbr:C21H25N5O8S2 dbr:ATC_code_J01CA10 dbr:ATCvet_code_QJ01CA10 dbr:Mezlin dbr:Mezlo dbr:Mezlocillin_sodium_monohydrate |
| is dbo:wikiPageWikiLink of | dbr:List_of_antibiotics dbr:List_of_MeSH_codes_(D02) dbr:Penicillin dbr:David_Hager dbr:Pseudomonas_aeruginosa dbr:Timeline_of_antibiotics dbr:Azlocillin dbr:C21H25N5O8S2 dbr:List_of_MeSH_codes_(D03) dbr:ATC_code_J01CA10 dbr:ATCvet_code_QJ01CA10 dbr:Mezlin dbr:ATC_code_J01 dbr:Ureidopenicillin dbr:Extended-spectrum_penicillin dbr:List_of_β-lactam_antibiotics dbr:Peptococcus dbr:List_of_drugs:_Meu–Mi dbr:Mezlo dbr:Mezlocillin_sodium_monohydrate |
| is foaf:primaryTopic of | wikipedia-en:Mezlocillin |
