| dbo:abstract |
N(6)-Carboxymethyllysine (CML), also known as N(epsilon)-(carboxymethyl)lysine, is an advanced glycation endproduct (AGE). CML has been the most used marker for AGEs in food analysis. Recently, it has been demonstrated that gut microbiota mediates an aging-associated decline in gut barrier function, allowing AGEs to leak into the bloodstream from the gut and impairing microglial function in the brain. It is suggested that the amount of CML in human blood samples may correlated with age. (en) N(ε)-カルボキシメチルリシン (CML、英語:N(ε)-Carboxymethyllysine)あるいはN(6)-(カルボキシメチル)リシンは、終末糖化産物 (AGEs)の一種である。CMLは食品分析においてAGEのマーカーとして最もよく用いられる。 (ja) N(6)-карбоксиметиллизин — производное лизина, образующееся в процессе реакции Майяра, самый распространённый конечный продукт гликирования. Является биомаркёром диабета. (ru) |
| dbo:iupacName |
(2S)-2-Amino-6-[(carboxymethyl)amino]hexanoic acid (en) |
| dbo:thumbnail |
wiki-commons:Special:FilePath/N(6)-carboxymethyllysine.svg?width=300 |
| dbo:wikiPageID |
11330158 (xsd:integer) |
| dbo:wikiPageLength |
3202 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1095892752 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Gamma-Glutamylcysteine dbc:Amino_acid_derivatives dbr:Advanced_glycation_endproduct |
| dbp:imagefile |
N-carboxymethyllysine.svg (en) |
| dbp:imagename |
Stereo, skeletal formula of N-carboxymethyllysine (en) |
| dbp:pin |
-2 (xsd:integer) |
| dbp:verifiedfields |
changed (en) |
| dbp:verifiedrevid |
420918695 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:wikiPageUsesTemplate |
dbt:Biochem-stub dbt:Chembox dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Cascite dbt:Chembox_Related dbt:Chemboximage dbt:Chemspidercite dbt:Ebicite dbt:Fdacite dbt:Stdinchicite |
| dcterms:subject |
dbc:Amino_acid_derivatives |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:WikicatAminoAcidDerivatives yago:Abstraction100002137 yago:Calculation105802185 yago:Cognition100023271 yago:DerivedFunction106014730 yago:HigherCognitiveProcess105770664 yago:ProblemSolving105796750 yago:Process105701363 yago:PsychologicalFeature100023100 dbo:ChemicalCompound yago:Thinking105770926 umbel-rc:ChemicalSubstanceType |
| rdfs:comment |
N(6)-Carboxymethyllysine (CML), also known as N(epsilon)-(carboxymethyl)lysine, is an advanced glycation endproduct (AGE). CML has been the most used marker for AGEs in food analysis. Recently, it has been demonstrated that gut microbiota mediates an aging-associated decline in gut barrier function, allowing AGEs to leak into the bloodstream from the gut and impairing microglial function in the brain. It is suggested that the amount of CML in human blood samples may correlated with age. (en) N(ε)-カルボキシメチルリシン (CML、英語:N(ε)-Carboxymethyllysine)あるいはN(6)-(カルボキシメチル)リシンは、終末糖化産物 (AGEs)の一種である。CMLは食品分析においてAGEのマーカーとして最もよく用いられる。 (ja) N(6)-карбоксиметиллизин — производное лизина, образующееся в процессе реакции Майяра, самый распространённый конечный продукт гликирования. Является биомаркёром диабета. (ru) |
| rdfs:label |
N(6)-Carboxymethyllysine (en) Nε-カルボキシメチルリシン (ja) Карбоксиметиллизин (ru) |
| owl:sameAs |
freebase:N(6)-Carboxymethyllysine yago-res:N(6)-Carboxymethyllysine wikidata:N(6)-Carboxymethyllysine http://azb.dbpedia.org/resource/ان(۶)-کربوکسی_متیلیسین dbpedia-fa:N(6)-Carboxymethyllysine dbpedia-ja:N(6)-Carboxymethyllysine dbpedia-ru:N(6)-Carboxymethyllysine dbpedia-sh:N(6)-Carboxymethyllysine dbpedia-sr:N(6)-Carboxymethyllysine https://global.dbpedia.org/id/64uFn |
| prov:wasDerivedFrom |
wikipedia-en:N(6)-Carboxymethyllysine?oldid=1095892752&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/N(6)-carboxymethyllysine.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:N(6)-Carboxymethyllysine |
| is dbo:wikiPageRedirects of |
dbr:N(6)-carboxymethyllysine dbr:Carboxymethyllysine |
| is dbo:wikiPageWikiLink of |
dbr:Procyanidin_B2 dbr:Gamma-L-Glutamyl-L-cysteine dbr:Argpyrimidine dbr:Advanced_glycation_end-product dbr:C8H16N2O4 dbr:CML dbr:N(6)-carboxymethyllysine dbr:Carboxymethyllysine |
| is foaf:primaryTopic of |
wikipedia-en:N(6)-Carboxymethyllysine |
