| dbo:abstract |
Nitrocefin ist ein Stoff aus der chemischen Gruppe der Cephalosporine, der seine Farbe bei der Spaltung durch β-Lactamasen von gelb nach rot verändert. (de) Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Beta-lactamase mediated resistance to beta-lactam antibiotics such as penicillin is a widespread mechanism of resistance for a number of bacteria including members of the family Enterobacteriaceae, a major group of enteric Gram-negative bacteria. Other methods for beta-lactamase detection exist including PCR; however, nitrocefin allows for rapid beta-lactamase detection using few materials and inexpensive equipment. (en) |
| dbo:casNumber |
41906-86-9 |
| dbo:chEMBL |
480517 |
| dbo:fdaUniiCode |
EWP54G0J8F |
| dbo:pubchem |
6436140 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Nitrocefin.svg?width=300 |
| dbo:wikiPageID |
38040677 (xsd:integer) |
| dbo:wikiPageLength |
6465 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1072399560 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Carbon dbr:Enterobacteriaceae dbr:Nitrogen dbr:Beta-lactamase dbr:Antimicrobial dbr:Beta-lactam dbr:Penicillin dbr:Penicillin_binding_proteins dbr:Carbonyl dbr:Polymerase_chain_reaction dbr:Colony_(biology) dbr:Peptidoglycan dbr:Visible_spectrum dbr:Bacteria dbc:Cephalosporin_antibiotics dbr:Cephalosporin dbr:Amide dbr:Gram-negative_bacteria dbr:Hydrolysis dbr:Antibiotic_resistance dbr:Chromogenic dbr:Ultraviolet dbr:Beta-lactam_antibiotic dbr:Beta-lactamases |
| dbp:c |
21 (xsd:integer) |
| dbp:casNumber |
41906 (xsd:integer) |
| dbp:chembl |
480517 (xsd:integer) |
| dbp:chemspiderid |
4940809 (xsd:integer) |
| dbp:h |
16 (xsd:integer) |
| dbp:iupacName |
-3 (xsd:integer) 2 (xsd:integer) 5 (xsd:integer) 8 (xsd:integer) |
| dbp:n |
4 (xsd:integer) |
| dbp:o |
8 (xsd:integer) |
| dbp:pubchem |
6436140 (xsd:integer) |
| dbp:s |
2 (xsd:integer) |
| dbp:smiles |
O=CN[C@@H]1CN2C=CCS[C@H]12 (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
LHNIIDJCEODSHA-OQRUQETBSA-N (en) |
| dbp:unii |
EWP54G0J8F (en) |
| dbp:verifiedrevid |
460017669 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Fdacite dbt:Stdinchicite |
| dct:subject |
dbc:Cephalosporin_antibiotics |
| gold:hypernym |
dbr:Substrate |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAntimicrobialDrugs yago:WikicatBeta-lactamAntibiotics yago:WikicatCephalosporinAntibiotics yago:Agent114778436 yago:Antibacterial102716205 yago:Antibiotic102716866 yago:CausalAgent100007347 yago:Drug103247620 yago:Matter100020827 yago:Medicine103740161 yago:PhysicalEntity100001930 dbo:ChemicalCompound dbo:Drug yago:Substance100020090 |
| rdfs:comment |
Nitrocefin ist ein Stoff aus der chemischen Gruppe der Cephalosporine, der seine Farbe bei der Spaltung durch β-Lactamasen von gelb nach rot verändert. (de) Nitrocefin is a chromogenic cephalosporin substrate routinely used to detect the presence of beta-lactamase enzymes produced by various microbes. Beta-lactamase mediated resistance to beta-lactam antibiotics such as penicillin is a widespread mechanism of resistance for a number of bacteria including members of the family Enterobacteriaceae, a major group of enteric Gram-negative bacteria. Other methods for beta-lactamase detection exist including PCR; however, nitrocefin allows for rapid beta-lactamase detection using few materials and inexpensive equipment. (en) |
| rdfs:label |
Nitrocefin (de) Nitrocefin (en) |
| owl:sameAs |
freebase:Nitrocefin yago-res:Nitrocefin wikidata:Nitrocefin dbpedia-de:Nitrocefin dbpedia-sh:Nitrocefin dbpedia-sr:Nitrocefin https://global.dbpedia.org/id/uKME |
| prov:wasDerivedFrom |
wikipedia-en:Nitrocefin?oldid=1072399560&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Nitrocefin.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Nitrocefin |
| is dbo:wikiPageWikiLink of |
dbr:Beta-lactamase dbr:Beta-lactam_antibiotics dbr:Cephalosporin |
| is foaf:primaryTopic of |
wikipedia-en:Nitrocefin |
