O-1602 (original) (raw)
O-1602 is a synthetic compound most closely related to abnormal cannabidiol, and more distantly related in structure to cannabinoid drugs such as THC. O-1602 does not bind to the classical cannabinoid receptors CB1 or CB2 with any significant affinity, but instead is an agonist at several other receptors which appear to be related to the cannabinoid receptors, particularly GPR18 and GPR55. These previously orphan receptors have been found to be targets for a number of endogenous and synthetic cannabinoid compounds, and are thought to be responsible for most of the non-CB1, non-CB2 mediated effects that have become evident in the course of cannabinoid research. O-1602 produces some effects shared with classical cannabinoid compounds such as analgesic and antiinflammatory effects and appetit
| Property | Value |
|---|---|
| dbo:abstract | O-1602 is a synthetic compound most closely related to abnormal cannabidiol, and more distantly related in structure to cannabinoid drugs such as THC. O-1602 does not bind to the classical cannabinoid receptors CB1 or CB2 with any significant affinity, but instead is an agonist at several other receptors which appear to be related to the cannabinoid receptors, particularly GPR18 and GPR55. These previously orphan receptors have been found to be targets for a number of endogenous and synthetic cannabinoid compounds, and are thought to be responsible for most of the non-CB1, non-CB2 mediated effects that have become evident in the course of cannabinoid research. O-1602 produces some effects shared with classical cannabinoid compounds such as analgesic and antiinflammatory effects and appetite stimulation, but it does not produce sedation or psychoactive effects, and has several actions in the gut and brain that are not shared with typical cannabinoid agonists. (en) |
| dbo:casNumber | 317321-41-8 |
| dbo:pubchem | 45073499 |
| dbo:thumbnail | wiki-commons:Special:FilePath/O-1602_structure.png?width=300 |
| dbo:wikiPageID | 38891969 (xsd:integer) |
| dbo:wikiPageLength | 4720 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1090852382 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Cannabidiol dbr:Cannabinoid_receptor dbr:GPR18 dbc:Cannabinoids dbc:Cyclohexenes dbr:Orphan_receptor dbr:GPR55 dbr:Abnormal_cannabidiol dbr:Analgesic dbr:THC dbr:Antiinflammatory dbr:O-1918 dbr:Cannabinoid |
| dbp:c | 17 (xsd:integer) |
| dbp:casNumber | 317321 (xsd:integer) |
| dbp:chemspiderid | 23014383 (xsd:integer) |
| dbp:h | 22 (xsd:integer) |
| dbp:iupacName | 5 (xsd:integer) |
| dbp:iupharLigand | 5525 (xsd:integer) |
| dbp:molecularWeight | 258.160000 (xsd:double) |
| dbp:o | 2 (xsd:integer) |
| dbp:pubchem | 45073499 (xsd:integer) |
| dbp:smiles | CC1=C[C@@H][C@H]CC1 (en) |
| dbp:stdinchi | 1 (xsd:integer) |
| dbp:stdinchikey | KDZOUSULXZNDJH-LSDHHAIUSA-N (en) |
| dbp:width | 220 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Cannabinoids dbt:Drugbox dbt:Reflist dbt:Short_description |
| dct:subject | dbc:Cannabinoids dbc:Cyclohexenes |
| gold:hypernym | dbr:Compound |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:ChemicalCompound dbo:Drug |
| rdfs:comment | O-1602 is a synthetic compound most closely related to abnormal cannabidiol, and more distantly related in structure to cannabinoid drugs such as THC. O-1602 does not bind to the classical cannabinoid receptors CB1 or CB2 with any significant affinity, but instead is an agonist at several other receptors which appear to be related to the cannabinoid receptors, particularly GPR18 and GPR55. These previously orphan receptors have been found to be targets for a number of endogenous and synthetic cannabinoid compounds, and are thought to be responsible for most of the non-CB1, non-CB2 mediated effects that have become evident in the course of cannabinoid research. O-1602 produces some effects shared with classical cannabinoid compounds such as analgesic and antiinflammatory effects and appetit (en) |
| rdfs:label | O-1602 (en) |
| owl:sameAs | freebase:O-1602 wikidata:O-1602 dbpedia-sh:O-1602 dbpedia-sr:O-1602 https://global.dbpedia.org/id/YMYd |
| prov:wasDerivedFrom | wikipedia-en:O-1602?oldid=1090852382&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/O-1602_structure.png |
| foaf:isPrimaryTopicOf | wikipedia-en:O-1602 |
| is dbo:wikiPageWikiLink of | dbr:List_of_psychedelic_drugs dbr:GPR55 dbr:4'-Fluorocannabidiol dbr:Abnormal_cannabidiol dbr:KLS-13019 dbr:Tetrahydrocannabiorcol dbr:C17H22O2 dbr:O-1918 dbr:Organix_Inc dbr:NAGly_receptor |
| is foaf:primaryTopic of | wikipedia-en:O-1602 |
