O-1871 (original) (raw)
O-1871 is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan at Organix Inc in 2002. It has a CB1 receptor affinity of 2.0nM and a CB2 receptor affinity of 0.3nM. Structurally, O-1871 is a cyclohexylphenol derivative related to CP 47,497, and so is illegal in some jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative, which are not cyclohexylphenol derivatives.
| Property | Value |
|---|---|
| dbo:abstract | O-1871 is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan at Organix Inc in 2002. It has a CB1 receptor affinity of 2.0nM and a CB2 receptor affinity of 0.3nM. Structurally, O-1871 is a cyclohexylphenol derivative related to CP 47,497, and so is illegal in some jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative, which are not cyclohexylphenol derivatives. (en) |
| dbo:casNumber | 620964-96-7 |
| dbo:fdaUniiCode | SGY2L36FDU |
| dbo:pubchem | 10405368 |
| dbo:thumbnail | wiki-commons:Special:FilePath/O-1871_structure.png?width=300 |
| dbo:wikiPageExternalLink | https://pubchem.ncbi.nlm.nih.gov/compound/21087754 https://pubchem.ncbi.nlm.nih.gov/compound/58803980 |
| dbo:wikiPageID | 39943711 (xsd:integer) |
| dbo:wikiPageLength | 3035 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1108882085 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Cannabicyclohexanol dbr:Cannabidiol dbr:O-1656 dbc:Cannabinoids dbr:CP_47,497 dbr:CP_55,940 dbc:2,6-Dihydroxybiphenyls dbr:Organix_Inc dbr:Cannabinoid dbr:Cannabinor dbr:Cannabinoid_receptor_1 dbr:Cannabinoid_receptor_2 dbr:File:O-1656_structure.png dbr:File:O-1660_structure.png |
| dbp:atcPrefix | none (en) |
| dbp:c | 23 (xsd:integer) |
| dbp:casNumber | 620964 (xsd:integer) |
| dbp:chemspiderid | 8580806 (xsd:integer) |
| dbp:h | 38 (xsd:integer) |
| dbp:iupacName | 2 (xsd:integer) |
| dbp:legalStatus | Banned as cyclohexylphenol derivative (en) |
| dbp:o | 2 (xsd:integer) |
| dbp:pubchem | 10405368 (xsd:integer) |
| dbp:smiles | CCCCCC1C2=CC=CC=C2O (en) |
| dbp:stdinchi | 1 (xsd:integer) |
| dbp:stdinchikey | WBSPBIRKSHKQQD-UHFFFAOYSA-N (en) |
| dbp:unii | SGY2L36FDU (en) |
| dbp:width | 280 (xsd:integer) |
| dbp:wikiPageUsesTemplate | dbt:Cannabinoid-stub dbt:Cannabinoids dbt:Clear-left dbt:Drugbox dbt:Reflist dbt:Short_description dbt:Cascite dbt:Fdacite |
| dcterms:subject | dbc:Cannabinoids dbc:2,6-Dihydroxybiphenyls |
| gold:hypernym | dbr:Agonist |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment | O-1871 is a potent cannabinoid agonist which was invented by Billy R Martin and Raj K Razdan at Organix Inc in 2002. It has a CB1 receptor affinity of 2.0nM and a CB2 receptor affinity of 0.3nM. Structurally, O-1871 is a cyclohexylphenol derivative related to CP 47,497, and so is illegal in some jurisdictions where CP 47,497 and its derivatives are banned. However the 3,3-dimethylcyclohexyl substituent of O-1871 can be replaced by various other groups, producing other potent compounds such as the cycloheptyl derivative O-1656 and the 2-adamantyl derivative O-1660, as well as the corresponding 3,5-dichlorophenyl derivative, which are not cyclohexylphenol derivatives. (en) |
| rdfs:label | O-1871 (en) |
| owl:sameAs | freebase:O-1871 wikidata:O-1871 dbpedia-sh:O-1871 dbpedia-sr:O-1871 https://global.dbpedia.org/id/Xorc |
| prov:wasDerivedFrom | wikipedia-en:O-1871?oldid=1108882085&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/O-1656_structure.png wiki-commons:Special:FilePath/O-1660_structure.png wiki-commons:Special:FilePath/O-1871_structure.png |
| foaf:isPrimaryTopicOf | wikipedia-en:O-1871 |
| is dbo:wikiPageWikiLink of | dbr:Cannabicyclohexanol dbr:List_of_psychedelic_drugs dbr:O-1656 dbr:CBD-DMH dbr:CP_47,497 dbr:Tetrahydrocannabiphorol dbr:C23H38O2 dbr:Organix_Inc dbr:Cannabinor dbr:Structural_scheduling_of_synthetic_cannabinoids |
| is foaf:primaryTopic of | wikipedia-en:O-1871 |
