Odevixibat, sold under the trade name Bylvay, is a medication for the treatment of progressive familial intrahepatic cholestasis (PFIC). It is taken by mouth. The most common side effects include diarrhea, abdominal pain, hemorrhagic diarrhea, soft feces, and hepatomegaly (enlarged liver). Odevixibat is a reversible, potent, selective inhibitor of the ileal bile acid transporter (IBAT). Odevixibat was approved for medical use in the United States and in the European Union in July 2021.
| Property |
Value |
| dbo:abstract |
Odevixibat, sold under the trade name Bylvay, is a medication for the treatment of progressive familial intrahepatic cholestasis (PFIC). It is taken by mouth. The most common side effects include diarrhea, abdominal pain, hemorrhagic diarrhea, soft feces, and hepatomegaly (enlarged liver). Odevixibat is a reversible, potent, selective inhibitor of the ileal bile acid transporter (IBAT). Odevixibat was approved for medical use in the United States and in the European Union in July 2021. (en) |
| dbo:alternativeName |
Bylvay (en) |
| dbo:casNumber |
501692-44-0 |
| dbo:chEMBL |
4297588 |
| dbo:drugbank |
DB16261 |
| dbo:fdaUniiCode |
2W150K0UUC |
| dbo:kegg |
D11716 |
| dbo:pubchem |
10153627 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Odevixibat_structure.png?width=300 |
| dbo:wikiPageExternalLink |
https://druginfo.nlm.nih.gov/drugportal/name/odevixibat |
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67731438 (xsd:integer) |
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10127 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1104107254 (xsd:integer) |
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dbr:Progressive_familial_intrahepatic_cholestasis dbc:Carboxylic_acids dbc:Phenols dbc:Tertiary_amines dbc:Thioethers dbr:Oral_administration dbr:Committee_for_Medicinal_Products_for_Human_Use dbc:Thiadiazepines dbc:Orphan_drugs dbr:European_Medicines_Agency dbc:Amides dbr:Hepatomegaly dbr:Ileal_bile_acid_transporter dbr:Medication dbr:Hemorrhagic |
| dbp:atcPrefix |
A05 (en) |
| dbp:atcSuffix |
AX05 (en) |
| dbp:c |
37 (xsd:integer) |
| dbp:casNumber |
501692 (xsd:integer) |
| dbp:chembl |
4297588 (xsd:integer) |
| dbp:chemspiderid |
8329135 (xsd:integer) |
| dbp:dailymedid |
Odevixibat (en) |
| dbp:drugbank |
DB16261 (en) |
| dbp:h |
48 (xsd:integer) |
| dbp:iupacName |
-2 (xsd:integer) |
| dbp:iupharLigand |
11194 (xsd:integer) |
| dbp:kegg |
D11716 (en) |
| dbp:legalEu |
Rx-only (en) |
| dbp:legalUs |
Rx-only (en) |
| dbp:n |
4 (xsd:integer) |
| dbp:o |
8 (xsd:integer) |
| dbp:pubchem |
10153627 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Oral_administration |
| dbp:s |
2 (xsd:integer) |
| dbp:smiles |
CCCCC1CNC2=CC=CC=C2SN1 (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
XULSCZPZVQIMFM-IPZQJPLYSA-N (en) |
| dbp:synonyms |
A4250 (en) |
| dbp:tradename |
Bylvay (en) |
| dbp:unii |
2 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Gastrointestinal-drug-stub dbt:Cite_web dbt:Infobox_drug dbt:Portal_bar dbt:Reflist dbt:Short_description dbt:Use_American_English dbt:Use_dmy_dates dbt:ClinicalTrialsGov dbt:Bile_and_liver_therapy |
| dcterms:subject |
dbc:Carboxylic_acids dbc:Phenols dbc:Tertiary_amines dbc:Thioethers dbc:Thiadiazepines dbc:Orphan_drugs dbc:Amides |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
Odevixibat, sold under the trade name Bylvay, is a medication for the treatment of progressive familial intrahepatic cholestasis (PFIC). It is taken by mouth. The most common side effects include diarrhea, abdominal pain, hemorrhagic diarrhea, soft feces, and hepatomegaly (enlarged liver). Odevixibat is a reversible, potent, selective inhibitor of the ileal bile acid transporter (IBAT). Odevixibat was approved for medical use in the United States and in the European Union in July 2021. (en) |
| rdfs:label |
Odevixibat (en) |
| owl:sameAs |
wikidata:Odevixibat https://global.dbpedia.org/id/BPvoj |
| prov:wasDerivedFrom |
wikipedia-en:Odevixibat?oldid=1104107254&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Odevixibat_structure.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Odevixibat |
| is dbo:wikiPageRedirects of |
dbr:Bylvay |
| is dbo:wikiPageWikiLink of |
dbr:Bylvay dbr:ATC_code_A05 |
| is foaf:primaryTopic of |
wikipedia-en:Odevixibat |
