| dbo:abstract |
Das Postsplenektomie-Syndrom (OPSI-Syndrom, engl. overwhelming postsplenectomy infection syndrome) ist eine besonders schwere Verlaufsform einer bakteriellen Infektion nach einer operativen Entfernung der Milz (Splenektomie). (de) An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen. The infections are typically characterized by either meningitis or sepsis, and are caused by encapsulated organisms including Streptococcus pneumoniae. It is a medical emergency and requires immediate treatment. Death has been reported to occur within 12 hours. The spleen is necessary for protection against encapsulated bacteria (see Mechanism) and as such when removed by splenectomy it can lead to rapid unchallenged infection by encapsulated bacteria. The rapid progression from mild viral symptoms to sepsis is one of the things that makes OPSI particularly dangerous. Another source of infection are species of Babesia, which are tick-borne parasites that cause babesiosis. Infection with Capnocytophaga canimorsus after dog bites can also cause the condition. (en) Posocznica posplenektomijna in. zespół OPSI (ang. overwhelming post-splenectomy infection (OPSI), overwhelming post-splenectomy sepsis (OPSS)) – posocznica o piorunującym przebiegu występująca u pacjentów z asplenią (faktyczny lub funkcjonalny brak śledziony). (pl) |
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| dbo:wikiPageWikiLink |
dbr:Patient_education dbr:Animal_bite dbr:Antibiotic dbr:Influenza-like_illness dbr:Spleen dbr:Coma dbr:Complement_system dbr:Meningitis dbr:Phagocytosis dbr:Pseudomonas_aeruginosa dbr:Malaise dbr:Malaria dbr:Hematologic_disease dbr:Pathogen dbr:Medical_advice dbr:Medical_emergency dbr:Medical_identification_tag dbr:Babesia dbr:Babesiosis dbr:Bacteria dbr:Centers_for_Disease_Control_and_Prevention dbr:E._coli dbr:Capnocytophaga_canimorsus dbr:Diarrhea dbr:Vomiting dbr:Protein dbr:Headache dbr:Hematological dbr:Bacterial_capsule dbr:Thalassemia dbr:Streptococcus_pneumoniae dbr:Asplenia dbr:Abdominal_pain dbc:Medical_emergencies dbc:Bacterial_diseases dbc:Spleen_(anatomy) dbr:Chills dbr:Blood dbr:Hemophilus_influenzae dbr:Dog_bite dbr:Splenectomy dbr:Infection dbr:Antibodies dbr:Sepsis dbr:Klebsiella_pneumoniae dbr:Infectious_disease dbr:Macrophage dbr:Septic_shock dbr:Shivering dbr:Neisseria_meningitidis dbr:Immunization dbr:Immunoglobulin_G dbr:Streptococcus_agalactiae dbr:Myalgia dbr:Polysaccharide dbr:Splenic_injury dbr:Reticuloendothelial_system dbr:Splenic_tumor dbr:Bacterial_capsules dbr:Phagocytose dbr:Salmonella_typhi dbr:Opsonization dbr:Opsonizer dbr:Human_immune_system dbr:Humoral dbr:Sickle-Cell_Anemia dbr:Green_book_on_immunisation |
| dbp:causes |
Exposure to pathogens following splenectomy or asplenia (en) |
| dbp:name |
Overwhelming post-splenectomy infection (en) |
| dbp:onset |
172800.0 (dbd:second) |
| dbp:prognosis |
Up to 99% mortality rate (en) |
| dbp:risks |
9.46728E7 (dbd:second) |
| dbp:specialty |
dbr:Infectious_disease |
| dbp:synonym |
Overwhelming post-splenectomy sepsis (en) |
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dbt:Reflist dbt:Infobox_medical_condition |
| dct:subject |
dbc:Medical_emergencies dbc:Bacterial_diseases dbc:Spleen_(anatomy) |
| rdf:type |
owl:Thing wikidata:Q12136 yago:WikicatMedicalEmergencies yago:Abstraction100002137 yago:Crisis107417644 yago:Emergency107417405 yago:Event100029378 yago:Happening107283608 yago:Juncture107416714 yago:PsychologicalFeature100023100 yago:YagoPermanentlyLocatedEntity dbo:Disease |
| rdfs:comment |
Das Postsplenektomie-Syndrom (OPSI-Syndrom, engl. overwhelming postsplenectomy infection syndrome) ist eine besonders schwere Verlaufsform einer bakteriellen Infektion nach einer operativen Entfernung der Milz (Splenektomie). (de) Posocznica posplenektomijna in. zespół OPSI (ang. overwhelming post-splenectomy infection (OPSI), overwhelming post-splenectomy sepsis (OPSS)) – posocznica o piorunującym przebiegu występująca u pacjentów z asplenią (faktyczny lub funkcjonalny brak śledziony). (pl) An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen. The infections are typically characterized by either meningitis or sepsis, and are caused by encapsulated organisms including Streptococcus pneumoniae. It is a medical emergency and requires immediate treatment. Death has been reported to occur within 12 hours. (en) |
| rdfs:label |
Postsplenektomie-Syndrom (de) Overwhelming post-splenectomy infection (en) Posocznica posplenektomijna (pl) |
| owl:sameAs |
freebase:Overwhelming post-splenectomy infection yago-res:Overwhelming post-splenectomy infection wikidata:Overwhelming post-splenectomy infection dbpedia-de:Overwhelming post-splenectomy infection dbpedia-pl:Overwhelming post-splenectomy infection https://global.dbpedia.org/id/zLr8 |
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wikipedia-en:Overwhelming_post-splenectomy_infection?oldid=1115603789&ns=0 |
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wikipedia-en:Overwhelming_post-splenectomy_infection |
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dbr:OPSI |
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dbr:Overwhelming_post-splenectomy_sepsis dbr:Overwhelming_post_splenectomy_infection |
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dbr:List_of_diseases_(O) dbr:OPSI dbr:Sickle_cell_disease dbr:Babesiosis dbr:Asplenia dbr:Spleen_transplantation dbr:Splenectomy dbr:Pneumococcal_infection dbr:Outline_of_emergency_medicine dbr:Splenic_infarction dbr:Overwhelming_post-splenectomy_sepsis dbr:Overwhelming_post_splenectomy_infection |
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wikipedia-en:Overwhelming_post-splenectomy_infection |