| dbo:abstract |
فيناسيميد (بالإنجليزية: Phenacemide) هو دواء يُستعمل في علاج: * نوبة جزئية مركبة (ar) Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity. (en) La fenacemide è un farmaco anticonvulsivante derivato dall'urea ed appartenente ad una categoria molto eterogenea di sostanze denominate ossazolidindioni. Sebbene il farmaco abbia una catena lineare caratterizzata da diversi gruppi di acetilurea, allo stato cristallino la molecole adotta una conformazione pseudociclica che la rende molto simile a quella della difenilidantoina e di altri composti eterociclici di tipo anticonvulsivante. (it) |
| dbo:alternativeName |
Phenurone (en) |
| dbo:casNumber |
63-98-9 |
| dbo:chEMBL |
918 |
| dbo:drugbank |
DB01121 |
| dbo:fdaUniiCode |
PAI7J52V09 |
| dbo:kegg |
D00504 |
| dbo:pubchem |
4753 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Phenacemide.svg?width=300 |
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6047975 (xsd:integer) |
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4516 (xsd:nonNegativeInteger) |
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| dbo:wikiPageWikiLink |
dbr:Epilepsy dbr:Anticonvulsant dbr:Hydantoin dbr:Structural_analog dbc:Ureas dbr:Congener_(chemistry) dbr:Barbiturate dbc:Imides dbr:British_Approved_Name dbc:Withdrawn_drugs dbr:International_Nonproprietary_Name dbr:Toxicity dbr:Ureide dbr:Pheneturide dbr:Phenytoin |
| dbp:atcPrefix |
N03 (en) |
| dbp:atcSuffix |
AX07 (en) |
| dbp:c |
9 (xsd:integer) |
| dbp:casNumber |
63 (xsd:integer) |
| dbp:chembl |
918 (xsd:integer) |
| dbp:chemspiderid |
4589 (xsd:integer) |
| dbp:drugbank |
DB01121 (en) |
| dbp:eliminationHalfLife |
-90000.0 |
| dbp:h |
10 (xsd:integer) |
| dbp:iupacName |
N-Carbamoyl-2-phenyl-acetamide (en) |
| dbp:iupharLigand |
7265 (xsd:integer) |
| dbp:kegg |
D00504 (en) |
| dbp:n |
2 (xsd:integer) |
| dbp:o |
2 (xsd:integer) |
| dbp:pubchem |
4753 (xsd:integer) |
| dbp:smiles |
O=CCc1ccccc1 (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
XPFRXWCVYUEORT-UHFFFAOYSA-N (en) |
| dbp:tradename |
Phenurone (en) |
| dbp:unii |
PAI7J52V09 (en) |
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464199698 (xsd:integer) |
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changed (en) |
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| dbp:wikiPageUsesTemplate |
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| dcterms:subject |
dbc:Ureas dbc:Imides dbc:Withdrawn_drugs |
| gold:hypernym |
dbr:Anticonvulsant |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatUreas yago:Abstraction100002137 yago:Acetamide114711197 yago:Amide114724264 yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Substance100019613 yago:Urea115085472 yago:WikicatAcetamides umbel-rc:DrugProduct |
| rdfs:comment |
فيناسيميد (بالإنجليزية: Phenacemide) هو دواء يُستعمل في علاج: * نوبة جزئية مركبة (ar) Phenacemide (INN, BAN) (brand name Phenurone), also known as phenylacetylurea, is an anticonvulsant of the ureide (acetylurea) class. It is a congener and ring-opened analogue of phenytoin (a hydantoin), and is structurally related to the barbiturates and to other hydantoins. Phenacemide was introduced in 1949 for the treatment of epilepsy, but was eventually withdrawn due to toxicity. (en) La fenacemide è un farmaco anticonvulsivante derivato dall'urea ed appartenente ad una categoria molto eterogenea di sostanze denominate ossazolidindioni. Sebbene il farmaco abbia una catena lineare caratterizzata da diversi gruppi di acetilurea, allo stato cristallino la molecole adotta una conformazione pseudociclica che la rende molto simile a quella della difenilidantoina e di altri composti eterociclici di tipo anticonvulsivante. (it) |
| rdfs:label |
فيناسيميد (ar) Fenacemide (it) Phenacemide (en) 苯乙酰脲 (zh) |
| owl:sameAs |
freebase:Phenacemide http://www4.wiwiss.fu-berlin.de/drugbank/resource/drugs/DB01121 yago-res:Phenacemide wikidata:Phenacemide dbpedia-ar:Phenacemide dbpedia-cy:Phenacemide dbpedia-it:Phenacemide dbpedia-sh:Phenacemide dbpedia-sr:Phenacemide dbpedia-zh:Phenacemide https://global.dbpedia.org/id/3TXjN |
| prov:wasDerivedFrom |
wikipedia-en:Phenacemide?oldid=1096809164&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Phenacemide.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Phenacemide |
| is dbo:wikiPageRedirects of |
dbr:C9H10N2O2 dbr:Carbanmide dbr:Phenacalum dbr:Phenacereum dbr:Phenacetur dbr:Phenarone dbr:Phenicarb dbr:Phenuron dbr:Phenurone dbr:Phenutal dbr:Phenyrit dbr:Phetylureum dbr:Epheron dbr:Epiclase dbr:ATC_code_N03AX07 dbr:ATCvet_code_QN03AX07 dbr:Felurea dbr:Fenacemid dbr:Fenacemide dbr:Fenacetamide dbr:Fenacetil-Karbamide dbr:Fenilep dbr:Fenised dbr:Fenostenyl dbr:Fenural dbr:Fenurea dbr:Fenurone dbr:Fenylacetylmocovina dbr:Fenytan dbr:Acetylureum dbr:Eferon dbr:Phacetur dbr:Cetylureum dbr:Comitiadone dbr:Neophedan dbr:Neophenal |
| is dbo:wikiPageWikiLink of |
dbr:List_of_compounds_with_carbon_number_9 dbr:Anticonvulsant dbr:C9H10N2O2 dbr:Carbanmide dbr:Phenacalum dbr:Phenacereum dbr:Phenacetur dbr:Phenarone dbr:Phenicarb dbr:Phenuron dbr:Phenurone dbr:Phenutal dbr:Phenyrit dbr:Phetylureum dbr:California_Proposition_65_list_of_chemicals dbr:Acylurea dbr:Epheron dbr:Epiclase dbr:ATC_code_N03AX07 dbr:ATCvet_code_QN03AX07 dbr:Felurea dbr:Fenacemid dbr:Fenacemide dbr:Fenacetamide dbr:Fenacetil-Karbamide dbr:Fenilep dbr:Fenised dbr:Fenostenyl dbr:Fenural dbr:Fenurea dbr:Fenurone dbr:Fenylacetylmocovina dbr:Fenytan dbr:ATC_code_N03 dbr:Acetylureum dbr:Eferon dbr:Pheneturide dbr:Phenylacetic_acid dbr:Phacetur dbr:Cetylureum dbr:Comitiadone dbr:List_of_drugs:_Pf–Ph dbr:Neophedan dbr:Neophenal |
| is foaf:primaryTopic of |
wikipedia-en:Phenacemide |
