Pierre Chambon (original) (raw)
Pierre Chambon (* 7. února 1931, Mylhúzy, Francie) je francouzský genetik. Známým se stal díky výzkumu . Je profesorem na College de France a ředitelem Institutu genetiky a molekulární buněčné biologie (Institut de Genetique et de Biologie Moleculaire et Cellulaire, IGBMC).
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| dbo:abstract | Pierre Chambon (* 7. února 1931, Mylhúzy, Francie) je francouzský genetik. Známým se stal díky výzkumu . Je profesorem na College de France a ředitelem Institutu genetiky a molekulární buněčné biologie (Institut de Genetique et de Biologie Moleculaire et Cellulaire, IGBMC). (cs) بيير شامبون من مواليد 7 فبراير 1931 في ميلوز، هو طبيب وعالم كيمياء حيوية وعالم وراثة فرنسي، وأستاذ فخري بكلية الطب بجامعة ستراسبورغ. أسس وأدار معهد علم الوراثة والبيولوجيا الجزيئية والخلوية حتى عام 2002. (ar) Pierre Chambon (* 7. Februar 1931 in Mülhausen, Elsass) ist ein französischer Genetiker. Chambon studierte Medizin an der Universität Straßburg, wo er 1958 promoviert wurde. Er war der langjährige Direktor (und Gründer) des Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) der Universität Straßburg in Illkirch-Graffenstaden und ist mit Gründer der École supérieure de biotechnologie de Strasbourg (ESBS). Er ist Mitglied der Académie des sciences und lehrt heute am Collège de France in Paris. Er ist Direktor des Institut clinique de la souris (ICS). Seine Untersuchungen von Proteinen, die an der Übersetzung genetischer Informationen durch zelluläre Botenstoffe beteiligt sind, gelten als bedeutend für die Zell- und Tumorbiologie. Er war ab den 1970er Jahren einer der Pioniere in der Anwendung moderner gentechnischer Verfahren in der Erforschung der Genregulation bei Eukaryoten-Zellen. Er identifizierte RNA-Polymerase II (B), verschiedene Transkriptions-Kontrollelemente und klonierte und untersuchte die Funktion von Kernrezeptoren für Hormone. Mit Ronald M. Evans entdeckte er den Rezeptor für Retinsäuren in der Zelle mit Anwendungen in der Tumorforschung und Entwicklungsbiologie. (de) Pierre Chambon, né le 7 février 1931 à Mulhouse, est un médecin, biochimiste et généticien français, professeur émérite de la faculté de médecine de l'université de Strasbourg. Il a fondé et dirigé l'Institut de génétique et de biologie moléculaire et cellulaire jusqu'en 2002. (fr) Pierre Chambon (born 7 February 1931 in Mulhouse, France) was the founder of the in Strasbourg, France. He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryotic genes and their modes of regulation. His major contributions to science include the identification of RNA polymerase II(B), the identification of transcriptional control elements, the cloning and dissection of nuclear hormone receptors, revealing their structure and showing how they contribute to human physiology. His group was also one of the first to demonstrate, biochemically and electron-microscopically, that the nucleosome is the smallest unit of chromatin (Cell, Vol. 4, 281–300, 1975). He accomplished much of his work in the 1970-90s. Chambon was elected a Foreign Associate of the US National Academy of Sciences and to the French Académie des Sciences in 1985, a foreign member of the Royal Swedish Academy of Sciences in 1987. He was awarded the Louisa Gross Horwitz Prize from Columbia University in 1999 and a second time in 2018. In 2003 he was awarded the March of Dimes Prize in Developmental Biology. He received the Albert Lasker Award for Basic Medical Research in 2004 for his work in the field. In 2010, Chambon was awarded the Gairdner Foundation International Award "for the elucidation of fundamental mechanisms of transcription in animal cells and to the discovery of the nuclear receptor superfamily". In 2018 he received the Louisa Gross Horwitz Prize for a second time. (en) ピエール・シャンボン（Pierre Chambon、1931年2月7日 - ）はフランス、ストラスブールのInstitute for Genetics and Cellular and Molecular Biologyの所長である。ミュルーズ出身。フランス科学アカデミーの会員になり、コレージュ・ド・フランスで教鞭を執る。 核内受容体（細胞核にあるステロイドホルモンなどの受容体）を発見し、その構造を明らかにし、どのように生理学に寄与するかを示したことで知られる。 (ja) Pierre Chambon (Mulhouse, 7 febbraio 1931) è un biologo francese. Chambon è stato eletto associato straniero della National Academy of Sciences degli Stati Uniti e dell'Académie des Sciences francese nel 1985, membro straniero della Royal Swedish Academy of Sciences nel 1987. Ha ricevuto il premio Louisa Gross Horwitz dalla Columbia University nel 1999. Nel 2003 gli è stato assegnato il in Biologia. Ha ricevuto il nel 2004. Nel 2010, Chambon è stato insignito del "per la spiegazione dei meccanismi fondamentali di trascrizione nelle cellule animali e per la scoperta della superfamiglia dei recettori nucleari". Nel 2018 ha ricevuto per la seconda volta il premio Louisa Gross Horwitz. (it) Pierre Chambon (ur. 7 lutego 1931 w Miluzie) – francuski lekarz, genetyk i biochemik. Emerytowany profesor Uniwersytetu w Strasburgu. Założył i był dyrektorem (fr.)(Institut de génétique et de biologie moléculaire et cellulaire, IGBMC). Znany z badań nad receptorami jądrowymi. Profesor College de France. (pl) Pierre Chambon, född 7 februari 1931 i Mulhouse, Frankrike, är en fransk medicinsk forskare. Hans mer kända forskningsinsatser gäller framför allt kärnreceptorer. Chambon är ledamot av Franska vetenskapsakademin, invaldes 1985 som utländsk medlem av The National Academy of Sciences och 1987 som utländsk ledamot av Kungliga Vetenskapsakademien. Han tilldelades Médaille d'or du CNRS 1979 och Albert Lasker Basic Medical Research Award 2004. (sv) Pierre Chambon (Mulhouse, 7 de fevereiro de 1931) foi um geneticista francês. (pt) 皮埃尔·尚邦（法語：Pierre Chambon，1931年2月7日－），出生于法国米卢斯，法国斯特拉斯堡的遗传、细胞和分子生物学研究所的创始人。他利用基因的克隆和测序技术的第一次破译真核生物基因的结构和它们的监管模式。他的主要科学贡献，包括RNA聚合酶II（B）、转录控制元件的识别、核激素受体的克隆和解剖，揭示了它们的结构和它们如何促进人的生理运作。他的大部分工作是在20世纪79至90年代完成的。 (zh) Пьер Шамбон (фр. Pierre Chambon; род. 7 февраля 1931, Мюлуз, Франция) — французский учёный. Труды в основном посвящены генетике, молекулярной биологии и биохимии. Лауреат многих престижных премий.Получил известность как исследователь белков и эукариотов. Идентифицировал поли(АДФ-рибоза)-полимеразы, структуру хроматина, нуклеосому, РНК-полимеразу II, энхансер, промотор. Является членом Французской академии наук, Европейской академии, EMBO, Академии Американской ассоциации исследований рака (2014), иностранным членом Национальной академии наук США (1985), Американской академии искусств и наук и Шведской королевской академии наук. В 1958 году получил степень доктора медицины в Страсбургском университете. (ru) |
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| rdfs:comment | Pierre Chambon (* 7. února 1931, Mylhúzy, Francie) je francouzský genetik. Známým se stal díky výzkumu . Je profesorem na College de France a ředitelem Institutu genetiky a molekulární buněčné biologie (Institut de Genetique et de Biologie Moleculaire et Cellulaire, IGBMC). (cs) بيير شامبون من مواليد 7 فبراير 1931 في ميلوز، هو طبيب وعالم كيمياء حيوية وعالم وراثة فرنسي، وأستاذ فخري بكلية الطب بجامعة ستراسبورغ. أسس وأدار معهد علم الوراثة والبيولوجيا الجزيئية والخلوية حتى عام 2002. (ar) Pierre Chambon, né le 7 février 1931 à Mulhouse, est un médecin, biochimiste et généticien français, professeur émérite de la faculté de médecine de l'université de Strasbourg. Il a fondé et dirigé l'Institut de génétique et de biologie moléculaire et cellulaire jusqu'en 2002. (fr) ピエール・シャンボン（Pierre Chambon、1931年2月7日 - ）はフランス、ストラスブールのInstitute for Genetics and Cellular and Molecular Biologyの所長である。ミュルーズ出身。フランス科学アカデミーの会員になり、コレージュ・ド・フランスで教鞭を執る。 核内受容体（細胞核にあるステロイドホルモンなどの受容体）を発見し、その構造を明らかにし、どのように生理学に寄与するかを示したことで知られる。 (ja) Pierre Chambon (Mulhouse, 7 febbraio 1931) è un biologo francese. Chambon è stato eletto associato straniero della National Academy of Sciences degli Stati Uniti e dell'Académie des Sciences francese nel 1985, membro straniero della Royal Swedish Academy of Sciences nel 1987. Ha ricevuto il premio Louisa Gross Horwitz dalla Columbia University nel 1999. Nel 2003 gli è stato assegnato il in Biologia. Ha ricevuto il nel 2004. Nel 2010, Chambon è stato insignito del "per la spiegazione dei meccanismi fondamentali di trascrizione nelle cellule animali e per la scoperta della superfamiglia dei recettori nucleari". Nel 2018 ha ricevuto per la seconda volta il premio Louisa Gross Horwitz. (it) Pierre Chambon (ur. 7 lutego 1931 w Miluzie) – francuski lekarz, genetyk i biochemik. Emerytowany profesor Uniwersytetu w Strasburgu. Założył i był dyrektorem (fr.)(Institut de génétique et de biologie moléculaire et cellulaire, IGBMC). Znany z badań nad receptorami jądrowymi. Profesor College de France. (pl) Pierre Chambon, född 7 februari 1931 i Mulhouse, Frankrike, är en fransk medicinsk forskare. Hans mer kända forskningsinsatser gäller framför allt kärnreceptorer. Chambon är ledamot av Franska vetenskapsakademin, invaldes 1985 som utländsk medlem av The National Academy of Sciences och 1987 som utländsk ledamot av Kungliga Vetenskapsakademien. Han tilldelades Médaille d'or du CNRS 1979 och Albert Lasker Basic Medical Research Award 2004. (sv) Pierre Chambon (Mulhouse, 7 de fevereiro de 1931) foi um geneticista francês. (pt) 皮埃尔·尚邦（法語：Pierre Chambon，1931年2月7日－），出生于法国米卢斯，法国斯特拉斯堡的遗传、细胞和分子生物学研究所的创始人。他利用基因的克隆和测序技术的第一次破译真核生物基因的结构和它们的监管模式。他的主要科学贡献，包括RNA聚合酶II（B）、转录控制元件的识别、核激素受体的克隆和解剖，揭示了它们的结构和它们如何促进人的生理运作。他的大部分工作是在20世纪79至90年代完成的。 (zh) Pierre Chambon (* 7. Februar 1931 in Mülhausen, Elsass) ist ein französischer Genetiker. Chambon studierte Medizin an der Universität Straßburg, wo er 1958 promoviert wurde. Er war der langjährige Direktor (und Gründer) des Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC) der Universität Straßburg in Illkirch-Graffenstaden und ist mit Gründer der École supérieure de biotechnologie de Strasbourg (ESBS). Er ist Mitglied der Académie des sciences und lehrt heute am Collège de France in Paris. Er ist Direktor des Institut clinique de la souris (ICS). (de) Pierre Chambon (born 7 February 1931 in Mulhouse, France) was the founder of the in Strasbourg, France. He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryotic genes and their modes of regulation. His major contributions to science include the identification of RNA polymerase II(B), the identification of transcriptional control elements, the cloning and dissection of nuclear hormone receptors, revealing their structure and showing how they contribute to human physiology. His group was also one of the first to demonstrate, biochemically and electron-microscopically, that the nucleosome is the smallest unit of chromatin (Cell, Vol. 4, 281–300, 1975). He accomplished much of his work in the 1970-90s. (en) Пьер Шамбон (фр. Pierre Chambon; род. 7 февраля 1931, Мюлуз, Франция) — французский учёный. Труды в основном посвящены генетике, молекулярной биологии и биохимии. Лауреат многих престижных премий.Получил известность как исследователь белков и эукариотов. Идентифицировал поли(АДФ-рибоза)-полимеразы, структуру хроматина, нуклеосому, РНК-полимеразу II, энхансер, промотор. В 1958 году получил степень доктора медицины в Страсбургском университете. (ru) |
| rdfs:label | بيير شامبون (ar) Pierre Chambon (cs) Pierre Chambon (de) Pierre Chambon (fr) Pierre Chambon (it) ピエール・シャンボン (ja) Pierre Chambon (en) Pierre Chambon (pl) Pierre Chambon (pt) Шамбон, Пьер (ru) Pierre Chambon (sv) 皮埃尔·尚邦 (zh) |
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