Pneumocandin B0 (original) (raw)
Pneumocandin B0, also known as pneumocandin B0, pneumocandin B(0), and hydroxy echinocandin, is an organic chemical compound with the formula C50H80N8O17, produced by the fungus . It is a strong antifungal and inhibits the synthesis of β-(1→3)-D-glucan, which is a fundamental component in most cell walls, like the Candida albicans membrane. This is a very important activity since there is an increase in the frequency of fungal infections, accompanied by an increase in the variety of opportunistic and pathogenic fungi such as Candida. This compound is used to synthesize caspofungin.
| Property | Value |
|---|---|
| dbo:abstract | Pneumocandin B0, also known as pneumocandin B0, pneumocandin B(0), and hydroxy echinocandin, is an organic chemical compound with the formula C50H80N8O17, produced by the fungus . It is a strong antifungal and inhibits the synthesis of β-(1→3)-D-glucan, which is a fundamental component in most cell walls, like the Candida albicans membrane. This is a very important activity since there is an increase in the frequency of fungal infections, accompanied by an increase in the variety of opportunistic and pathogenic fungi such as Candida. This compound is used to synthesize caspofungin. Pneumocandin B0 can be easily confused with pneumocandin B, although they have different side chains and residues. (en) |
| dbo:alternativeName | CHEMBL269311; 135575-42-7; Pneumocandin B0; Hydroxy Echinocandin; SCHEMBL8444763 (en) |
| dbo:iupacName | N-{(2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-[(1S)-3-Amino-1-hydroxy-3-oxopropyl]-23-[(1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl]-2,11,12,15-tetrahydroxy-6-[(1S)-1-hydroxyethyl]-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl}-10,12-dimethyltetradecanamide (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Pneumocandin_B0.svg?width=300 |
| dbo:wikiPageExternalLink | http://www.chemicalbook.com/ChemicalProductProperty_EN_CB51120636.htm |
| dbo:wikiPageID | 48249088 (xsd:integer) |
| dbo:wikiPageLength | 9158 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1043793174 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Candida_(fungus) dbr:Carbon dbr:Caspofungin dbr:Nitrogen dbr:Antifungal dbr:Hydrogen dbr:Pathogenic_fungus dbc:Heterocyclic_compounds_with_3_rings dbc:Nitrogen_heterocycles dbr:Gene_cluster dbr:Leucine dbr:Whole_genome_sequencing dbr:Lipopeptide dbr:Ethanol dbr:Oxygen dbr:Cell_wall dbr:Residue_(chemistry) dbc:Antifungals dbr:Echinocandin dbr:Homopolysaccharide dbr:Dimethyl_sulfoxide dbr:Dimethylformamide dbr:Methanol dbr:Candida_albicans dbr:Pneumocystis_jirovecii dbr:Glarea_lozoyensis dbr:File:Pneumocandin_B0_(HQ).png |
| dbp:imagefile | Pneumocandin B0.svg (en) |
| dbp:imagesize | 300 (xsd:integer) |
| dbp:iupacname | 120.0 |
| dbp:name | Pneumocandin B0 (en) |
| dbp:othernames | CHEMBL269311; 135575-42-7; Pneumocandin B0; Hydroxy Echinocandin; SCHEMBL8444763 (en) |
| dbp:wikiPageUsesTemplate | dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Main_article dbt:Reflist dbt:Cascite dbt:Fdacite dbt:Antifungals |
| dcterms:subject | dbc:Heterocyclic_compounds_with_3_rings dbc:Nitrogen_heterocycles dbc:Antifungals |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound |
| rdfs:comment | Pneumocandin B0, also known as pneumocandin B0, pneumocandin B(0), and hydroxy echinocandin, is an organic chemical compound with the formula C50H80N8O17, produced by the fungus . It is a strong antifungal and inhibits the synthesis of β-(1→3)-D-glucan, which is a fundamental component in most cell walls, like the Candida albicans membrane. This is a very important activity since there is an increase in the frequency of fungal infections, accompanied by an increase in the variety of opportunistic and pathogenic fungi such as Candida. This compound is used to synthesize caspofungin. (en) |
| rdfs:label | Pneumocandin B0 (en) |
| owl:sameAs | wikidata:Pneumocandin B0 https://global.dbpedia.org/id/2MaMx |
| prov:wasDerivedFrom | wikipedia-en:Pneumocandin_B0?oldid=1043793174&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Pneumocandin_B0.svg wiki-commons:Special:FilePath/Pneumocandin_B0_(HQ).png |
| foaf:isPrimaryTopicOf | wikipedia-en:Pneumocandin_B0 |
| foaf:name | Pneumocandin B0 (en) |
| is dbo:wikiPageRedirects of | dbr:Pneumocandin_Bo dbr:Hydroxy_Echinocandin dbr:PneumocandinB0 dbr:Pneumocandin_B(0) |
| is dbo:wikiPageWikiLink of | dbr:Caspofungin dbr:Pneumocandin_Bo dbr:Hydroxy_Echinocandin dbr:PneumocandinB0 dbr:Pneumocandin_B(0) |
| is foaf:primaryTopic of | wikipedia-en:Pneumocandin_B0 |
