| dbo:abstract |
Propylpyrazoletriol (PPT) is a synthetic, nonsteroidal agonist of ERα with 400-fold selectivity over ERβ that is used widely in scientific research to study the function of ERα. Though originally thought to be highly selective for ERα, PPT has subsequently been found to also act as an agonist of the GPER (GPR30). (en) 丙基吡唑三醇（Propylpyrazoletriol，PPT），是一种合成激动剂，选择性是的400倍，常用於研究ERα的功能。最初科學家認爲PPT對ERα有高度选择性，唯後來發現PPT也可作（G蛋白偶聯雌激素受體1，GPR30）激动剂。 (zh) |
| dbo:casNumber |
263717-53-9 |
| dbo:fdaUniiCode |
0T83Y6JZPF |
| dbo:pubchem |
6095481 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Propylpyrazoletriol.svg?width=300 |
| dbo:wikiPageID |
48938164 (xsd:integer) |
| dbo:wikiPageLength |
3542 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1015044777 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:ERA-45 dbr:ERA-63 dbc:Ketones dbc:Phenols dbc:Synthetic_estrogens dbr:GPER dbr:GTx-758 dbr:Agonist dbc:Pyrazoles dbr:Nonsteroidal dbr:Scientific_research dbc:GPER_agonists dbr:Methylpiperidinopyrazole dbr:Estrogen_receptor_alpha dbr:Synthetic_compound dbr:ERβ |
| dbp:c |
24 (xsd:integer) |
| dbp:casNumber |
263717 (xsd:integer) |
| dbp:chemspiderid |
16142497 (xsd:integer) |
| dbp:h |
22 (xsd:integer) |
| dbp:iupacName |
4 (xsd:integer) |
| dbp:n |
2 (xsd:integer) |
| dbp:o |
3 (xsd:integer) |
| dbp:pubchem |
6095481 (xsd:integer) |
| dbp:smiles |
CCCC1=CC4=CC=CO (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
UOSWGERPQQOSHS-UHFFFAOYSA-N (en) |
| dbp:unii |
0 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Drugbox dbt:Estrogen_receptor_modulators dbt:Pharmacology-stub dbt:Reflist dbt:Fdacite |
| dcterms:subject |
dbc:Ketones dbc:Phenols dbc:Synthetic_estrogens dbc:Pyrazoles dbc:GPER_agonists |
| gold:hypernym |
dbr:Agonist |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug |
| rdfs:comment |
Propylpyrazoletriol (PPT) is a synthetic, nonsteroidal agonist of ERα with 400-fold selectivity over ERβ that is used widely in scientific research to study the function of ERα. Though originally thought to be highly selective for ERα, PPT has subsequently been found to also act as an agonist of the GPER (GPR30). (en) 丙基吡唑三醇（Propylpyrazoletriol，PPT），是一种合成激动剂，选择性是的400倍，常用於研究ERα的功能。最初科學家認爲PPT對ERα有高度选择性，唯後來發現PPT也可作（G蛋白偶聯雌激素受體1，GPR30）激动剂。 (zh) |
| rdfs:label |
Propylpyrazoletriol (en) 丙基吡唑三醇 (zh) |
| owl:sameAs |
wikidata:Propylpyrazoletriol dbpedia-zh:Propylpyrazoletriol https://global.dbpedia.org/id/2MkFX yago-res:Propylpyrazoletriol |
| prov:wasDerivedFrom |
wikipedia-en:Propylpyrazoletriol?oldid=1015044777&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Propylpyrazoletriol.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Propylpyrazoletriol |
| is dbo:wikiPageDisambiguates of |
dbr:PPT |
| is dbo:wikiPageRedirects of |
dbr:Propyl-pyrazole-triol dbr:Propyl-pyrazoletriol dbr:Propyl_pyrazole_triol dbr:Propyl_pyrazoletriol dbr:Propylpyrazole-triol dbr:Propylpyrazole_triol |
| is dbo:wikiPageWikiLink of |
dbr:ERA-45 dbr:ERA-63 dbr:(R,R)-Tetrahydrochrysene dbr:16α-LE2 dbr:Liquiritigenin dbr:PPT dbr:GPER dbr:GTx-758 dbr:PHTPP dbr:Methylpiperidinopyrazole dbr:Estrogen_receptor_alpha dbr:Estrogen_receptor_beta dbr:Nonsteroidal_estrogen dbr:Propyl-pyrazole-triol dbr:Propyl-pyrazoletriol dbr:Propyl_pyrazole_triol dbr:Propyl_pyrazoletriol dbr:Propylpyrazole-triol dbr:Propylpyrazole_triol |
| is foaf:primaryTopic of |
wikipedia-en:Propylpyrazoletriol |
