| dbo:abstract |
The enzyme protein serine/threonine phosphatase (EC 3.1.3.16; systematic name protein-serine/threonine-phosphate phosphohydrolase) is a form of phosphoprotein phosphatase that acts upon phosphorylated serine/threonine residues: [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate Serine and threonine phosphates are stable under physiological conditions, so a phosphatase enzyme has to remove the phosphate to reverse the regulation signal. Ser/Thr-specific protein phosphatases are regulated partly by their location within the cell and by specific inhibitor proteins. Serine and threonine are amino acids which have similar side-chain compositions that contain a hydroxyl group and thus can be phosphorylated by enzymes called serine/threonine protein kinases. The addition of the phosphate group can be reversed by enzymes called serine/threonine phosphatases. The addition and removal of phosphate groups regulates many cellular pathways involved in cell proliferation, programmed cell death (apoptosis), embryonic development, and cell differentiation. (en) |
| dbo:ecNumber |
3.1.3.16 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/5muf.jpg?width=300 |
| dbo:wikiPageExternalLink |
http://phosphatome.net/wiki/index.php/Phosphatase_Subfamily_PPP2C |
| dbo:wikiPageID |
30128701 (xsd:integer) |
| dbo:wikiPageLength |
2353 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1105306738 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Enzyme_inhibitor dbc:EC_3.1.3 dbr:PPP4C dbr:PPP6C dbr:Phosphoprotein_phosphatase dbr:Protein_Phosphatase_2 dbr:Calcineurin dbr:Cell_(biology) dbr:Threonine dbr:Serine dbr:PPP5C dbr:PPP1 |
| dbp:caption |
Protein serine/threonine phosphatase dodecamer, Human (en) |
| dbp:casNumber |
9025 (xsd:integer) |
| dbp:ecNumber |
3.100000 (xsd:double) |
| dbp:iubmbEcNumber |
3 (xsd:integer) |
| dbp:name |
protein-serine/threonine phosphatase (en) |
| dbp:width |
270 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:EC_number dbt:Enzymes dbt:Esterases dbt:Hydrolase-stub dbt:Infobox_enzyme dbt:Portal_bar dbt:Reflist dbt:Intracellular_signaling_peptides_and_proteins |
| dct:subject |
dbc:EC_3.1.3 |
| gold:hypernym |
dbr:Form |
| rdf:type |
owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8047 yago:Abstraction100002137 yago:Activator114723079 yago:Catalyst114723628 yago:Chemical114806838 yago:Compound114818238 yago:Enzyme114732946 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Enzyme yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatEnzymes |
| rdfs:comment |
The enzyme protein serine/threonine phosphatase (EC 3.1.3.16; systematic name protein-serine/threonine-phosphate phosphohydrolase) is a form of phosphoprotein phosphatase that acts upon phosphorylated serine/threonine residues: [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate (en) |
| rdfs:label |
Protein serine/threonine phosphatase (en) |
| owl:sameAs |
freebase:Protein serine/threonine phosphatase wikidata:Protein serine/threonine phosphatase https://global.dbpedia.org/id/4u7FN |
| prov:wasDerivedFrom |
wikipedia-en:Protein_serine/threonine_phosphatase?oldid=1105306738&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/5muf.jpg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Protein_serine/threonine_phosphatase |
| foaf:name |
protein-serine/threonine phosphatase (en) |
| is dbo:wikiPageRedirects of |
dbr:Serine/threonine_protein_phosphatase dbr:Serine/threonine_specific_protein_phosphatase dbr:Phosphoprotein_phosphohydrolase dbr:EC_3.1.3.16 |
| is dbo:wikiPageWikiLink of |
dbr:Protein_phosphatase_1 dbr:Protein_phosphatase_2 dbr:List_of_EC_numbers_(EC_3) dbr:CDC25A dbr:Okadaic_acid dbr:Serine/threonine-specific_protein_kinase dbr:Myosin-light-chain_phosphatase dbr:Serine/threonine_protein_phosphatase dbr:Serine/threonine_specific_protein_phosphatase dbr:Phosphoprotein_phosphohydrolase dbr:EC_3.1.3.16 |
| is foaf:primaryTopic of |
wikipedia-en:Protein_serine/threonine_phosphatase |
