Psymberin (original) (raw)
La psymberina, también conocida como irciniastatina A, es una citotoxina derivada de las esponjas de mar. Fue descubierta por dos grupos de investigadores independientes en 2004. Se descubrió que la psymberina era altamente bioactiva ya que mostró LC50 a concentraciones nanomolares contra varios tipos de tumores.
| Property | Value |
|---|---|
| dbo:abstract | La psymberina, también conocida como irciniastatina A, es una citotoxina derivada de las esponjas de mar. Fue descubierta por dos grupos de investigadores independientes en 2004. Se descubrió que la psymberina era altamente bioactiva ya que mostró LC50 a concentraciones nanomolares contra varios tipos de tumores. (es) Psymberin, also known as irciniastatin A, is a cytotoxin derived from sea sponges. It was discovered by two independent research groups, one led by Dr. Phil Crews and one led by Dr. Jean Schmidt, in 2004. Psymberin was found to be highly bioactive as it showed LC50s at nanomolar concentrations against various types of tumors. (en) |
| dbo:alternativeName | irciniastatin A (en) |
| dbo:iupacName | (2S,3S)-N-((S)-((2S,4R,6R)-6-((2S,3R)-3-((R)-6,8-dihydroxy-5-methyl-1-oxoisochroman-3-yl)-2-hydroxybutyl)-4-hydroxy-5,5-dimethyltetrahydro-2H-pyran-2-yl)(methoxy)methyl)-2-hydroxy-3-methoxy-5-methylhex-5-enamide (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/psymberin.png?width=300 |
| dbo:wikiPageID | 21344883 (xsd:integer) |
| dbo:wikiPageLength | 4539 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1054562944 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Roman_numerals dbr:Pederin dbc:Sponge_toxins dbr:Genes dbr:Condensation_domain dbr:Tumor dbr:Cytotoxin dbr:Protein dbr:Biological_activity dbr:Phillip_Crews dbr:Clade dbr:Polyketide_synthase dbr:Paederus dbr:LC50 dbr:Sea_sponge dbr:File:Psymberinbiosynthesis.tif |
| dbp:imagefile | psymberin.png (en) |
| dbp:imagesize | 250 (xsd:integer) |
| dbp:iupacname | -N--2-hydroxy-3-methoxy-5-methylhex-5-enamide (en) |
| dbp:othernames | irciniastatin A (en) |
| dbp:wikiPageUsesTemplate | dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:MeshName dbt:Reflist |
| dcterms:subject | dbc:Sponge_toxins |
| gold:hypernym | dbr:Cytotoxin |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:Matter100020827 yago:PhysicalEntity100001930 yago:Poison115032376 yago:WikicatInvertebrateToxins dbo:ChemicalCompound yago:Substance100020090 yago:Toxin115034074 |
| rdfs:comment | La psymberina, también conocida como irciniastatina A, es una citotoxina derivada de las esponjas de mar. Fue descubierta por dos grupos de investigadores independientes en 2004. Se descubrió que la psymberina era altamente bioactiva ya que mostró LC50 a concentraciones nanomolares contra varios tipos de tumores. (es) Psymberin, also known as irciniastatin A, is a cytotoxin derived from sea sponges. It was discovered by two independent research groups, one led by Dr. Phil Crews and one led by Dr. Jean Schmidt, in 2004. Psymberin was found to be highly bioactive as it showed LC50s at nanomolar concentrations against various types of tumors. (en) |
| rdfs:label | Psymberina (es) Psymberin (en) |
| owl:sameAs | freebase:Psymberin yago-res:Psymberin wikidata:Psymberin dbpedia-es:Psymberin dbpedia-vi:Psymberin https://global.dbpedia.org/id/4toCL |
| prov:wasDerivedFrom | wikipedia-en:Psymberin?oldid=1054562944&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/psymberin.png |
| foaf:isPrimaryTopicOf | wikipedia-en:Psymberin |
| is dbo:wikiPageWikiLink of | dbr:Pederin dbr:Krische_allylation dbr:Phillip_Crews |
| is foaf:primaryTopic of | wikipedia-en:Psymberin |
