Qrr RNA (original) (raw)

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Qrr (Quorum regulatory RNA) is a non-coding RNA that is thought to be involved in the regulation of quorum sensing in Vibrio species. It is believed that these RNAs, guided by a protein, Hfq, can mediate the destabilisation of the quorum-sensing master regulators LuxR/HapR/VanT mRNAs. There are 5 different qrr genes (Qrr1–5) in V. harveyi; of these, qrr2, 3 and 4 are activated by LuxR.

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dbo:abstract Qrr (Quorum regulatory RNA) is a non-coding RNA that is thought to be involved in the regulation of quorum sensing in Vibrio species. It is believed that these RNAs, guided by a protein, Hfq, can mediate the destabilisation of the quorum-sensing master regulators LuxR/HapR/VanT mRNAs. Qrr operates as part of a negative feedback loop which regulates the shift in cell state from that of low density populations to that in high density populations. In Vibrio harveyi, Qrr binds and represses expression of the luxR mRNA transcript, a master regulator of quorum-sensing genes. At higher population densities, increased autoinducer concentration leads to termination of qrr transcription hence derepression of luxR. There are 5 different qrr genes (Qrr1–5) in V. harveyi; of these, qrr2, 3 and 4 are activated by LuxR. (en)
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dbo:wikiPageWikiLink dbr:MRNA dbr:Vibrio_harveyi dbc:Non-coding_RNA dbr:Protein dbr:Quorum_sensing dbr:Hfq_protein dbr:Autoinducer dbr:Negative_feedback dbr:Vibrio dbr:Non-coding_RNA
dbp:altsymbols Qrr1–5 (en)
dbp:id RF00378 (en)
dbp:name Qrr RNA (en) Quorum regulatory RNA (en)
dbp:rfam RF00378 (en)
dbp:rnaType sRNA (en)
dbp:symbol Qrr (en)
dbp:taxDomain Vibrio (en)
dbp:width 270 (xsd:integer)
dbp:wikiPageUsesTemplate dbt:Cite_journal dbt:Reflist dbt:Short_description dbt:Infobox_rfam dbt:Rfam
dcterms:subject dbc:Non-coding_RNA
gold:hypernym dbr:RNA
rdf:type dbo:Protein
rdfs:comment Qrr (Quorum regulatory RNA) is a non-coding RNA that is thought to be involved in the regulation of quorum sensing in Vibrio species. It is believed that these RNAs, guided by a protein, Hfq, can mediate the destabilisation of the quorum-sensing master regulators LuxR/HapR/VanT mRNAs. There are 5 different qrr genes (Qrr1–5) in V. harveyi; of these, qrr2, 3 and 4 are activated by LuxR. (en)
rdfs:label Qrr RNA (en)
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prov:wasDerivedFrom wikipedia-en:Qrr_RNA?oldid=1032051970&ns=0
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