Rakesh Jain (original) (raw)

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Ракеш Джайн (англ. Rakesh K. Jain, род. 18 декабря 1950) — индийско-американский учёный, специалист в области биологии рака и химии.Профессор Гарвардской медицинской школы, а прежде Университета Карнеги — Меллона, сотрудник Массачусетской больницы общего профиля и Массачусетского технологического института, член Национальных Академии наук (2009), (2003) и Инженерной (2004) академий США (лишь один из девятерых, удостоенных такого тройного членства), иностранный член Индийской национальной академии наук (2015).Удостоен Национальной научной медали (2013).В 2014—2017 годах приводится Thomson Reuters в числе 1 % наиболее цитируемых исследователей в области клинической медицины.

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dbo:abstract Rakesh Kumar Jain (* 18. Dezember 1950 in Lalitpur) ist ein indisch-US-amerikanischer Tumorbiologe und Chemiker. Jain studierte am Indian Institute of Technology in Kanpur Chemieingenieurwesen mit dem Bachelor-Abschluss 1972 und an der University of Delaware in Newark mit dem Master-Abschluss 1974 und der Promotion bei James Wei 1975. Er war 1976 bis 1978 Assistant Professor für Biomedizin-Technik und Chemie an der Columbia University und ab 1978 an der Carnegie Mellon University, an der er 1979 Associate Professor wurde und 1983 eine volle Professor erhielt. Ab 1991 war er Direktor des Edwin L. Steele Laboratory for Tumor Biology des Massachusetts General Hospital sowie Professor am MIT und an der Harvard Medical School (A. Werk Cook Professor of Radiation Oncology (Tumor Biology)). Er untersucht die Mikro-Umgebung von Tumoren, die Mikrozirkulation in deren Umgebung, Wärmehaushalt im Tumorgewebe und Transport von Molekülen im Tumor, Rheologie maligner und nicht-maligner Zellen (Metastasen-Ausbreitung) und Wechselwirkung mit Gefäßwänden (Tumor-Wirt-Wechselwirkung). Dabei entwickelte er auch Methoden Tumoren in vivo bildlich darzustellen (unter anderem mit speziellen gentechnisch veränderten Mausstämmen und chirurgisch implantierten transparenten Fenstern), Medikamente an die Tumoren heranzuführen und neue Therapieansätze aufgrund von Erkenntnissen über die Mikroumgebung von Tumoren wie eine Anti-Angiogenese Therapie, die darauf beruht die abnorme Tumor-Blutgefäßbildung zu normalisieren (vascular normalization) und so zum Beispiel eine bessere Chemotherapie zu ermöglichen. Weitere Ansatzpunkte sind die Manipulation der extrazellulären Matrix von Tumoren, die ebenfalls ein Hindernis für die Chemotherapie sein kann, indem sie die Blutzufuhr behindert. Er arbeitet interdisziplinär und mit unmittelbarer klinischer Anwendung (Bench to Bedside). Jain ist Mitglied der National Academy of Sciences, der American Academy of Arts and Sciences, der National Academy of Engineering, der National Academy of Medicine und der American Association for the Advancement of Science. Er ist Ehrendoktor der Duke University, der Katholischen Universität Löwen und des IIT in Kanpur. 1990/91 erhielt er einen Humboldt-Forschungspreis, mit dem er an den Universitäten Mainz und München war. 2014 erhielt er die National Medal of Science. 1983/84 war er Guggenheim Fellow. Es gibt einen gleichnamigen aus Indien stammenden Chemiker (* 1956) am Roswell Park Cancer Institute, der synthetische Antigene entwickelt. (de) Rakesh K. Jain (born 1950) is the Andrew Werk Cook Professor of Tumor Biology at Massachusetts General Hospital in the Harvard Medical School and Director of the E.L. Steele Laboratories for Tumor Biology at the Massachusetts General Hospital. He has mentored more than 200 graduate and postdoctoral students from over a dozen different disciplines. Jain's research findings are summarized in more than 600 publications, which have been cited more than 70,000 times (as of December, 2015). He was among the top 1% cited researchers in Clinical Medicine in 2014-15. He serves or has served on advisory panels to government, industry and academia, and is a member of editorial advisory boards of 22 journals, including Nature Reviews Cancer and Nature Reviews Clinical Oncology. He has received more than 75 awards from engineering and medical professional societies/institutions. He was elected a member of the National Academy of Engineering in 2004 for the integration of bioengineering with tumor biology and imaging gene expression and functions in vivo for drug delivery in tumors. He is also a member of the National Academy of Medicine, the National Academy of Sciences and the American Academy of Arts and Sciences. In 2014, he was chosen as one of 50 Oncology Luminaries on the occasion of the 50th anniversary of the American Society of Clinical Oncology. In 2015, Jain received honorary doctorates from Duke University, KU Leuven, Belgium and IIT-Kanpur, India. In 2013, he was awarded the National Medal of Science. (en) Ракеш Джайн (англ. Rakesh K. Jain, род. 18 декабря 1950) — индийско-американский учёный, специалист в области биологии рака и химии.Профессор Гарвардской медицинской школы, а прежде Университета Карнеги — Меллона, сотрудник Массачусетской больницы общего профиля и Массачусетского технологического института, член Национальных Академии наук (2009), (2003) и Инженерной (2004) академий США (лишь один из девятерых, удостоенных такого тройного членства), иностранный член Индийской национальной академии наук (2015).Удостоен Национальной научной медали (2013).В 2014—2017 годах приводится Thomson Reuters в числе 1 % наиболее цитируемых исследователей в области клинической медицины. (ru)
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dbp:academicAdvisors Pietro M. Gullino (en)
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dbp:awards American Association for Cancer Research (en) National Academy of Sciences (en) National Medal of Science (en) Guggenheim Fellowship (en) National Academy of Engineering (en) National Academy of Medicine (en) Elected to American Academy of Arts and Sciences (en) Founding Fellow, American Institute for Medical and Biological Engineering (en) Whitaker Distinguished Lecturer, Biomedical Engineering Society (en) ASCO Science of Oncology Award and Lecture (en) Eugene M. Landis Award, Microcirculatory Society (en) Outstanding Investigator Grant, NIH (en) Princess Takamatsu Lecture/Award (en) Academic Scientist of the Year, 2005 Pharmaceutical Achievement Awards (en) Benjamin Zweifach Distinguished Lecture, The City College, New York (en)
dbp:birthDate 1950-12-18 (xsd:date)
dbp:doctoralAdvisor James Wei (en)
dbp:fields Chemical Engineering, Bioengineering, Tumor Biology (en)
dbp:knownFor Tumor pathophysiology, Tumor normalization (en)
dbp:name Rakesh K. Jain (en)
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rdfs:comment Ракеш Джайн (англ. Rakesh K. Jain, род. 18 декабря 1950) — индийско-американский учёный, специалист в области биологии рака и химии.Профессор Гарвардской медицинской школы, а прежде Университета Карнеги — Меллона, сотрудник Массачусетской больницы общего профиля и Массачусетского технологического института, член Национальных Академии наук (2009), (2003) и Инженерной (2004) академий США (лишь один из девятерых, удостоенных такого тройного членства), иностранный член Индийской национальной академии наук (2015).Удостоен Национальной научной медали (2013).В 2014—2017 годах приводится Thomson Reuters в числе 1 % наиболее цитируемых исследователей в области клинической медицины. (ru) Rakesh Kumar Jain (* 18. Dezember 1950 in Lalitpur) ist ein indisch-US-amerikanischer Tumorbiologe und Chemiker. Jain studierte am Indian Institute of Technology in Kanpur Chemieingenieurwesen mit dem Bachelor-Abschluss 1972 und an der University of Delaware in Newark mit dem Master-Abschluss 1974 und der Promotion bei James Wei 1975. Er war 1976 bis 1978 Assistant Professor für Biomedizin-Technik und Chemie an der Columbia University und ab 1978 an der Carnegie Mellon University, an der er 1979 Associate Professor wurde und 1983 eine volle Professor erhielt. Ab 1991 war er Direktor des Edwin L. Steele Laboratory for Tumor Biology des Massachusetts General Hospital sowie Professor am MIT und an der Harvard Medical School (A. Werk Cook Professor of Radiation Oncology (Tumor Biology)). (de) Rakesh K. Jain (born 1950) is the Andrew Werk Cook Professor of Tumor Biology at Massachusetts General Hospital in the Harvard Medical School and Director of the E.L. Steele Laboratories for Tumor Biology at the Massachusetts General Hospital. (en)
rdfs:label Rakesh K. Jain (de) Rakesh Jain (en) Джайн, Ракеш (ru)
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