Riligustilide is a nonsteroidal phytoprogestogen that is found in Ligusticum chuanxiong. It is a very weak agonist of the progesterone receptor (EC50 ≈ 81 μM). Another compound in the plant, 3,8-dihydrodiligustilide, is also a phytoprogestogen, but is almost 1,000-fold more potent in comparison (EC50 = 90 nM).
| Property |
Value |
| dbo:abstract |
Riligustilide is a nonsteroidal phytoprogestogen that is found in Ligusticum chuanxiong. It is a very weak agonist of the progesterone receptor (EC50 ≈ 81 μM). Another compound in the plant, 3,8-dihydrodiligustilide, is also a phytoprogestogen, but is almost 1,000-fold more potent in comparison (EC50 = 90 nM). (en) |
| dbo:iupacName |
(3S,3′Z,5′aR,6′S,7′aS)-3′-Butylidene-6′-propylspiro[4,5-dihydro-2-benzofuran-3,7′-5,5a,6,7a-tetrahydro-4H-cyclobuta[g][2]benzofuran]-1,1′-dione (en) |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Riligustilide.svg?width=300 |
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52730805 (xsd:integer) |
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2629 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1104973141 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Potency_(pharmacology) dbr:EC50 dbc:Alkene_derivatives dbc:Lactones dbc:Progestogens dbc:Spiro_compounds dbr:Ligusticum_chuanxiong dbr:Progesterone_receptor dbr:Agonist dbr:Nonsteroidal dbc:Cyclobutanes dbr:Tanaproget dbr:Kaempferol dbr:Phytoprogestogen dbr:3,8-dihydrodiligustilide |
| dbp:imagefile |
Riligustilide.svg (en) |
| dbp:imagesize |
250 (xsd:integer) |
| dbp:iupacname |
-3 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Genito-urinary-drug-stub dbt:Progesterone_receptor_modulators dbt:Reflist dbt:Fdacite |
| dcterms:subject |
dbc:Alkene_derivatives dbc:Lactones dbc:Progestogens dbc:Spiro_compounds dbc:Cyclobutanes |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound |
| rdfs:comment |
Riligustilide is a nonsteroidal phytoprogestogen that is found in Ligusticum chuanxiong. It is a very weak agonist of the progesterone receptor (EC50 ≈ 81 μM). Another compound in the plant, 3,8-dihydrodiligustilide, is also a phytoprogestogen, but is almost 1,000-fold more potent in comparison (EC50 = 90 nM). (en) |
| rdfs:label |
Riligustilide (en) |
| owl:sameAs |
yago-res:Riligustilide wikidata:Riligustilide https://global.dbpedia.org/id/2d7N6 |
| prov:wasDerivedFrom |
wikipedia-en:Riligustilide?oldid=1104973141&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Riligustilide.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Riligustilide |
| is dbo:wikiPageWikiLink of |
dbr:Ligusticum_striatum dbr:3,8-Dihydrodiligustilide dbr:C24H28O4 dbr:Phytoprogestogen |
| is foaf:primaryTopic of |
wikipedia-en:Riligustilide |
