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رولف هاسلر (بالألمانية: Rolf Hassler) هو عالم أمراض ألماني، ولد في 1914، وتوفي في 1984. (ar) Rolf Hassler (1914-1984) est un neuropathologiste allemand qui est l'auteur d'importantes découvertes sur la physiopathologie et le traitement de la maladie de Parkinson. En 1938, il démontre par des études autopsiques que la structure la plus touchée dans la maladie de Parkinson est la substantia nigra (en), tandis que le striatum et le globus pallidus sont intacts. Il découvre dans cette région une perte neuronale et la présence de corps de Lewy en abondance. Ces résultats confirment les théories de (en), qui en 1919 avait prédit que la substantia nigra devait être la principale structure cérébrale atteinte. Hassler a ensuite été directeur de l'Institut Max-Planck pour la recherche sur le cerveau à Francfort-sur-le-Main, où il poursuit ses études sur la maladie de Parkinson, devenant un pionnier de la chirurgie du tremblement. (fr) Rolf Hassler (1914–1984) was a German pathologist who made important discoveries on the pathophisiology and treatment of Parkinson's disease (PD). In 1938 he published the autopsies of PD patients that showed while the striatum and globus pallidus were mostly unaffected and the main affected structure was the substantia nigra pars compacta; it lost many neurons and also held abundant Lewy bodies. Such findings confirmed Konstantin Tretiakoff's theories, who in 1919 had reported that the substantia nigra was the main cerebral structure affected. Hassler later was the director of the Max-Planck-Institut für Hirnforschung at Frankfurt am Main where he continued his studies on PD, becoming a pioneer in surgery for tremors. (en) |
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رولف هاسلر (بالألمانية: Rolf Hassler) هو عالم أمراض ألماني، ولد في 1914، وتوفي في 1984. (ar) Rolf Hassler (1914–1984) was a German pathologist who made important discoveries on the pathophisiology and treatment of Parkinson's disease (PD). In 1938 he published the autopsies of PD patients that showed while the striatum and globus pallidus were mostly unaffected and the main affected structure was the substantia nigra pars compacta; it lost many neurons and also held abundant Lewy bodies. Such findings confirmed Konstantin Tretiakoff's theories, who in 1919 had reported that the substantia nigra was the main cerebral structure affected. (en) Rolf Hassler (1914-1984) est un neuropathologiste allemand qui est l'auteur d'importantes découvertes sur la physiopathologie et le traitement de la maladie de Parkinson. En 1938, il démontre par des études autopsiques que la structure la plus touchée dans la maladie de Parkinson est la substantia nigra (en), tandis que le striatum et le globus pallidus sont intacts. Il découvre dans cette région une perte neuronale et la présence de corps de Lewy en abondance. Ces résultats confirment les théories de (en), qui en 1919 avait prédit que la substantia nigra devait être la principale structure cérébrale atteinte. (fr) |
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