SDZ SER-082 (original) (raw)

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dbo:abstract SDZ SER-082 is a drug which acts as a mixed antagonist for the 5-HT2B and 5-HT2C serotonin receptors, with good selectivity over other serotonin receptor subtypes and slight preference for 5-HT2C over 5-HT2B. It has been used in animal studies into the behavioural effects of the different 5-HT2 subtypes, and how they influence the effects of other drugs such as cocaine. (en)
dbo:casNumber 141474-54-6
dbo:fdaUniiCode M7FHF24Q22
dbo:pubchem 9859407
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dbp:c 15 (xsd:integer)
dbp:casNumber 141474 (xsd:integer)
dbp:chemspiderid 8035107 (xsd:integer)
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dbp:iupacName -cis 4,5,7a,8,9,10,11,11a-octahydro-7H-10-methylindolo[1,7-bc][2,6]-naphthyridine (en)
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dbp:pubchem 9859407 (xsd:integer)
dbp:smiles CN1CC[C@@H]2CN3CCC4=C3C[C@@H]2C1 (en)
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dbp:stdinchikey YASBOGFWAMXINH-TZMCWYRMSA-N (en)
dbp:unii M7FHF24Q22 (en)
dbp:verifiedfields changed (en)
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dct:subject dbc:Indolonaphthyridines dbc:5-HT2_antagonists
gold:hypernym dbr:Drug
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rdfs:comment SDZ SER-082 is a drug which acts as a mixed antagonist for the 5-HT2B and 5-HT2C serotonin receptors, with good selectivity over other serotonin receptor subtypes and slight preference for 5-HT2C over 5-HT2B. It has been used in animal studies into the behavioural effects of the different 5-HT2 subtypes, and how they influence the effects of other drugs such as cocaine. (en)
rdfs:label SDZ SER-082 (en)
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