| dbo:alternativeName |
Xadago, Onstryv (en) |
| dbo:bioavailability |
95.000000 (xsd:float) |
| dbo:casNumber |
133865-89-1 202825-46-5 |
| dbo:chEBI |
134718 |
| dbo:chEMBL |
396778 48582 |
| dbo:description |
chemische Verbindung (de) composto chimico (it) composto químico (pt) cheemesch Verbindung (lb) chemická sloučenina (cs) chemická zlúčenina (sk) chemiese verbinding (af) chemische verbinding (nl) component quimic (oc) compositum chemicum (la) compost químic (ca) composto químico (gl) composé chimique (fr) compuesto quimico (an) compuestu químicu (ast) compus chimic (ro) kemia kombinaĵo (eo) kemiallinen yhdiste (fi) kemisk forbindelse (da) kemična spojina (sl) kjemisk sambinding (nn) komponim kimik (sq) konposatu kimiko (eu) senyawa kimia (in) związek chemiczny (pl) ķīmisks savienojums (lv) քիմիական միացություն (hy) תרכובת (iw) مركب كيميائي (ar) کیٖمیٲیی مُرَکَب (ks) রাসায়নিক যৌগ (bn) medicamento indicado para el tratamiento de la enfermedad de Parkinson (es) drug indicated for the treatment of Parkinson's disease (en) |
| dbo:drugbank |
DB06654 |
| dbo:fdaUniiCode |
90ENL74SIG |
| dbo:kegg |
D10158 D10191 |
| dbo:pubchem |
131682 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Safinamide.svg?width=300 |
| dbo:wikiPageExternalLink |
https://druginfo.nlm.nih.gov/drugportal/name/safinamide https://druginfo.nlm.nih.gov/drugportal/name/safinamide%20mesylate |
| dbo:wikiPageWikiLink |
dbr:Zambon dbc:Merck_brands dbr:Bioavailability dbr:Mydriasis dbr:Diabetic_neuropathy dbr:Diclofenac dbr:Idiopathic_disease dbr:Tyramine dbr:Dyskinesia dbr:Psychomotor_agitation dbr:Placebo dbr:Selective_serotonin_reuptake_inhibitor dbr:Serotonin_syndrome dbr:Carboxylic_acid dbr:Cytochrome_P450 dbr:Dextromethorphan dbr:Monoamine_oxidase_inhibitor dbr:Pitavastatin dbr:Sigma-1_receptor dbr:Dopamine_reuptake_inhibitor dbr:Pharmacia dbc:Monoamine_oxidase_inhibitors dbc:Sodium_channel_blockers dbr:Metabolism dbr:Glucuronidation dbr:Retinopathy dbr:Kidney dbr:Blood_plasma dbr:Ciprofloxacin dbr:Tetracyclic_antidepressant dbr:Tricyclic_antidepressant dbr:Pravastatin dbr:Amidase dbc:Dopamine_reuptake_inhibitors dbc:Calcium_channel_blockers dbr:Epilepsy dbr:Hypertension dbr:Albinism dbr:Calcium_channel_blocker dbr:European_Medicines_Agency dbr:CYP3A4 dbr:Methotrexate dbr:Rasagiline dbr:Nausea dbr:Food_and_Drug_Administration dbr:Parkinson's_disease dbc:Fluoroarenes dbc:Serotonin_reuptake_inhibitors dbr:Glucuronide dbc:Propionamides dbr:Levodopa dbr:Retinitis_pigmentosa dbr:Oral_administration dbr:Uveitis dbr:Dopamine dbr:Retina dbr:Opioids dbc:Sigma_receptor_ligands dbr:IC50 dbr:Pethidine dbr:Microsome dbr:Management_of_Parkinson's_disease dbr:ABCG2 dbr:Sigma_receptor dbr:Sodium_channel_blocker dbr:Serotonin_reuptake_inhibitor dbr:Orthostatic_hypotension dbr:Faeces dbr:Glutamate dbr:Monoamine_oxidase_B dbr:Sigma-2_receptor dbr:Upjohn dbr:Selegiline dbr:Merck-Serono dbr:Merck_KGaA dbr:Elimination_half-life dbr:Organic_anion_transporter_3 dbr:Plasma_proteins dbr:Pharmaceutical_drug dbr:First-pass_metabolism dbr:Serotonin–noradrenaline_reuptake_inhibitor dbr:Farmitalia-Carlo_Erba dbr:Hypertensive_crises dbr:International_Nonproprietary_Name dbr:Phase_III_clinical_trial dbr:Newron_Pharmaceuticals dbr:4-[(3-fluorophenyl)methoxy]phenyl]_methylamino]propanamide dbr:File:Safinamide_metabolism.svg |
| dbp:atcPrefix |
N04 (en) |
| dbp:atcSuffix |
BD03 (en) |
| dbp:bioavailability |
95.0 (dbd:perCent) |
| dbp:c |
17 (xsd:integer) |
| dbp:casNumber |
133865 (xsd:integer) 202825 (xsd:integer) |
| dbp:chebi |
134718 (xsd:integer) |
| dbp:chembl |
48582 (xsd:integer) 396778 (xsd:integer) |
| dbp:chemspiderid |
116349 (xsd:integer) |
| dbp:displayAuthors |
6 (xsd:integer) |
| dbp:drugbank |
DB06654 (en) |
| dbp:eliminationHalfLife |
-108000.0 (dbd:second) |
| dbp:excretion |
76 (xsd:integer) |
| dbp:f |
1 (xsd:integer) |
| dbp:h |
19 (xsd:integer) |
| dbp:imageClass |
skin-invert-image (en) |
| dbp:index2Label |
mesylate (en) |
| dbp:iupacName |
N2-{4-[oxy]benzyl}-(L)-alaninamide (en) |
| dbp:iupharLigand |
8291 (xsd:integer) |
| dbp:kegg |
D10158 (en) D10191 (en) |
| dbp:legalCa |
Rx-only (en) |
| dbp:legalEu |
Rx-only (en) |
| dbp:legalUk |
POM (en) |
| dbp:legalUs |
Rx-only (en) |
| dbp:metabolism |
Amidases, glucuronidation (en) |
| dbp:n |
2 (xsd:integer) |
| dbp:nameListStyle |
vanc (en) |
| dbp:o |
2 (xsd:integer) |
| dbp:pregnancyCategory |
Fetal malformations in animal studies (en) |
| dbp:proteinBound |
88 (xsd:integer) |
| dbp:pubchem |
131682 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Oral_administration |
| dbp:smiles |
O=C[C@@H]C (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
NEMGRZFTLSKBAP-LBPRGKRZSA-N (en) |
| dbp:synonyms |
-2 (xsd:integer) EMD-1195686, PNU-15774E; (en) |
| dbp:tradename |
Xadago, Onstryv (en) |
| dbp:unii |
90 (xsd:integer) |
| dbp:verifiedfields |
changed (en) |
| dbp:verifiedrevid |
464386010 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:width |
250 (xsd:integer) |
| dbp:wikiPageUsesTemplate |
dbt:Authority_control dbt:Clear_left dbt:Reflist dbt:Infobox_drug dbt:Keggcite dbt:Portal_bar dbt:Ebicite dbt:Ion_channel_modulators dbt:Cascite dbt:Chemspidercite dbt:Stdinchicite dbt:Use_dmy_dates dbt:Sigma_receptor_modulators dbt:Monoamine_metabolism_modulators dbt:Drugbankcite dbt:Monoamine_reuptake_inhibitors dbt:Drugs.com dbt:Fdacite dbt:Cs1_config dbt:Short_description dbt:Antiparkinson |
| dct:subject |
dbc:Drugs_developed_by_Merck dbc:Antidyskinetic_agents dbc:Monoamine_oxidase_inhibitors dbc:Sodium_channel_blockers dbc:Dopamine_reuptake_inhibitors dbc:Calcium_channel_blockers dbc:3-Fluorophenyl_compounds dbc:Serotonin_reuptake_inhibitors dbc:Propionamides dbc:Sigma_receptor_ligands |
| gold:hypernym |
dbr:Drug |
| rdf:type |
owl:Thing dul:ChemicalObject wikidata:Q8386 dbo:ChemicalSubstance |
| rdfs:label |
Safinamide (en) سافيناميد (ar) Safinamida (es) Safinamid (de) Safinamide (it) Сафинамид (ru) |
| owl:sameAs |
freebase:Safinamide yago-res:Safinamide wikidata:Safinamide dbpedia-it:Safinamide dbpedia-de:Safinamide dbpedia-he:Safinamide dbpedia-ro:Safinamide dbpedia-es:Safinamide dbpedia-ru:Safinamide dbpedia-ar:Safinamide dbpedia-la:Safinamide dbpedia-sh:Safinamide dbpedia-sr:Safinamide dbpedia-global:Safinamide |
| prov:wasDerivedFrom |
wikipedia-en:Safinamide?oldid=1292970993&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Safinamide.svg wiki-commons:Special:FilePath/Safinamide_metabolism.svg |
| foaf:isPrimaryTopicOf |
wikipedia-en:Safinamide |
| is dbo:wikiPageRedirects of |
dbr:Onstryv dbr:Xadago dbr:Safinamide_mesylate dbr:Safinamide_methanesulfonate |
| is dbo:wikiPageWikiLink of |
dbr:Zambon dbr:ATC_code_N04 dbr:Monoamine_oxidase_inhibitor dbr:Ralfinamide dbr:Parkinson's_disease dbr:List_of_dopaminergic_drugs dbr:List_of_adrenergic_drugs dbr:Monoamine_oxidase_B dbr:C17H19FN2O2 dbr:Onstryv dbr:Xadago dbr:Safinamide_mesylate dbr:Safinamide_methanesulfonate |
| is foaf:primaryTopic of |
wikipedia-en:Safinamide |
