Sialogogue (original) (raw)
Un sialogogue est un aliment, une substance naturelle ou chimique, capable de stimuler la sécrétion salivaire.
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| dbo:abstract | Un sialogogue est un aliment, une substance naturelle ou chimique, capable de stimuler la sécrétion salivaire. (fr) A sialogogue (also spelled sialagogue, ptysmagogue or ptyalagogue) is a drug or substance that increases the flow rate of saliva. Sialogogues can be used in the treatment of xerostomia (the subjective feeling of having a dry mouth), to stimulate any functioning salivary gland tissue to produce more saliva. Saliva has a bactericidal effect, so when low levels of it are secreted, the risk of caries increases. Not only this, but fungal infections such as oral candidosis also can be a consequence of low salivary flow rates. The buffer effect of saliva is also important, neutralising acids that cause tooth enamel demineralisation. The following are used in dentistry to treat xerostomia: * Parasympathomimetic drugs act on parasympathetic muscarinic receptors to induce an increased saliva flow. The M3 receptor has been identified as the principal target to increase salivary flow rates. Pilocarpine is an example; the maximum dose of this drug is 30 mg/day. Contraindications include many lung conditions, such as asthma, cardiac problems, epilepsy and Parkinson's disease; side effects include flushing, increased urination, increase perspiration, and GI disturbances. * Chewing gum induces stimulated saliva secretion of the minor salivary glands in the oral cavity. During mastication (chewing), the resultant compression forces acting on the periodontal ligament cause the stimulated release of gingival crevicular fluid. Further salivation can be also achieved by the stimulation of taste receptors (parasympathetic fibers from the chorda tympani and the lingual nerve are involved). * Malic and ascorbic acid are effective sialogogues, but are not ideal as they cause demineralisation of tooth enamel. (en) |
| dbo:wikiPageID | 6133004 (xsd:integer) |
| dbo:wikiPageLength | 3748 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1089993442 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Gentiana dbr:Gentiana_lutea dbr:Pyrethrum dbr:Zingiber dbr:Chrysanthemum dbr:Bloodroot dbr:Chorda_tympani dbr:Buffer_solution dbc:Drugs dbc:Otorhinolaryngology dbr:Cayenne_pepper dbr:Drug dbr:Ginger dbr:Heliopsis_longipes dbr:Iris_(plant) dbr:Iris_versicolor dbr:Lingual_nerve dbr:Capsicum dbr:Centaurium dbr:Centaurium_erythraea dbr:Caries dbr:Tooth_enamel dbr:Ireland dbr:Hypersalivation dbr:Acmella dbr:Acmella_oleracea dbc:Dentistry dbr:Salivary_gland dbr:Pilocarpine dbr:Polygala dbr:Candidosis dbr:Saliva dbr:Zanthoxylum dbr:Zanthoxylum_americanum dbr:Xerostomia dbr:Sanguinaria dbr:Senega dbr:Muscarinic_receptors dbr:Periodontal_ligament |
| dbp:wikiPageUsesTemplate | dbt:Reflist |
| dct:subject | dbc:Drugs dbc:Otorhinolaryngology dbc:Dentistry |
| gold:hypernym | dbr:Drug |
| rdf:type | yago:Agent114778436 yago:CausalAgent100007347 yago:Drug103247620 yago:Matter100020827 yago:PhysicalEntity100001930 dbo:Drug yago:Substance100020090 yago:WikicatDrugs |
| rdfs:comment | Un sialogogue est un aliment, une substance naturelle ou chimique, capable de stimuler la sécrétion salivaire. (fr) A sialogogue (also spelled sialagogue, ptysmagogue or ptyalagogue) is a drug or substance that increases the flow rate of saliva. Sialogogues can be used in the treatment of xerostomia (the subjective feeling of having a dry mouth), to stimulate any functioning salivary gland tissue to produce more saliva. Saliva has a bactericidal effect, so when low levels of it are secreted, the risk of caries increases. Not only this, but fungal infections such as oral candidosis also can be a consequence of low salivary flow rates. The buffer effect of saliva is also important, neutralising acids that cause tooth enamel demineralisation. The following are used in dentistry to treat xerostomia: (en) |
| rdfs:label | Sialogogue (fr) Sialogogue (en) |
| owl:sameAs | freebase:Sialogogue yago-res:Sialogogue wikidata:Sialogogue dbpedia-fr:Sialogogue https://global.dbpedia.org/id/3Cfxm |
| prov:wasDerivedFrom | wikipedia-en:Sialogogue?oldid=1089993442&ns=0 |
| foaf:isPrimaryTopicOf | wikipedia-en:Sialogogue |
| is dbo:wikiPageRedirects of | dbr:Sialagogue |
| is dbo:wikiPageWikiLink of | dbr:Sialadenitis dbr:Dysgeusia dbr:Acmella_oleracea dbr:Meth_mouth dbr:Challacombe_scale dbr:Xerostomia dbr:Sialagogue |
| is foaf:primaryTopic of | wikipedia-en:Sialogogue |