Siderophage (original) (raw)
心臓病細胞（しんぞうびょうさいぼう、英:heart failure cell）とは細胞質内に多量のヘモジデリンを含有している肺胞マクロファージ。心機能障害、肺の鬱血が存在するときに認められる。心不全細胞とも。
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| dbo:abstract | Als Siderophagen werden Makrophagen bezeichnet, die Hämosiderin, ein Abbauprodukt des Blutfarbstoffes Hämoglobin, phagozytiert haben. Dem histologischen oder zytologischen Nachweis von Siderophagen kommt in der Pathologie diagnostische Bedeutung als Hinweis auf ältere Einblutungen zu. Nach einer Subarachnoidalblutung können sie beispielsweise im Liquor cerebrospinalis nachgewiesen werden. In den Lungenalveolen finden sich Siderophagen als sogenannte „Herzfehlerzellen“ bei chronischer Lungenstauung, z. B. im Rahmen einer chronischen Linksherzinsuffizienz. Mit Berliner Blau können sie selektiv angefärbt werden. (de) A siderophage is a hemosiderin-containing macrophage. Heart failure cells are siderophages generated in the alveoli of the lungs of people with left heart failure or chronic pulmonary edema, when the high pulmonary blood pressure causes red blood cells to pass through the vascular wall. Siderophages are not specific of heart failure. They are present wherever red blood cells encounter macrophages, such as pulmonary hemorrhage. In left heart failure, the left ventricle can not keep pace with the incoming blood from the pulmonary veins. The resulting backup causes increased pressure on the alveolar capillaries, and red blood cells leak out. Alveolar macrophages (dust cells) engulf the red blood cells, and become engorged with brownish hemosiderin. In chronic pulmonary edema, alveolar septa become thick and fibrous, again increasing pressure on alveolar capillaries and resulting in leakage of red blood cells which undergo phagocytosis by alveolar macrophages. (en) 心臓病細胞（しんぞうびょうさいぼう、英:heart failure cell）とは細胞質内に多量のヘモジデリンを含有している肺胞マクロファージ。心機能障害、肺の鬱血が存在するときに認められる。心不全細胞とも。 (ja) Um siderófago é um macrófago que contém hemossiderina. As células da insuficiência cardíaca são siderófagos de alvéolos de pacientes com insuficiência cardíaca esquerda ou edema pulmonar crônico, quando a hipertensão pulmonar faz com que os glóbulos vermelhos passem pela parede vascular. Os siderófagos não são específicos da insuficiência cardíaca. Eles estão presentes em processos nos quais glóbulos vermelhos encontram macrófagos, como na hemorragia pulmonar . (pt) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Histopathology_of_sid...ic_pulmonary_congestion.jpg?width=300 |
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| dbo:wikiPageLength | 2016 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1071228343 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Capillaries dbr:Pulmonary_alveolus dbr:Pulmonary_edema dbr:Pulmonary_hypertension dbr:Phagocytosis dbr:Pulmonary_hemorrhage dbr:Left_ventricle dbr:Hemosiderin dbc:Macrophages dbr:Heart_failure dbr:Alveolar_macrophage dbr:Red_blood_cell dbr:Pulmonary_veins dbr:Red_blood_cells dbr:Lung dbr:Macrophage dbr:File:Histopathology_of_siderophage_in_chronic_pulmonary_congestion.jpg dbr:File:Siderophages_in_endometriotic_focus.jpg |
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| dcterms:subject | dbc:Macrophages |
| rdf:type | yago:WikicatMacrophages yago:Cell100006484 yago:LivingThing100004258 yago:Macrophage105450740 yago:Object100002684 yago:Phagocyte105450888 yago:PhysicalEntity100001930 yago:SomaticCell105430628 yago:Whole100003553 |
| rdfs:comment | 心臓病細胞（しんぞうびょうさいぼう、英:heart failure cell）とは細胞質内に多量のヘモジデリンを含有している肺胞マクロファージ。心機能障害、肺の鬱血が存在するときに認められる。心不全細胞とも。 (ja) Um siderófago é um macrófago que contém hemossiderina. As células da insuficiência cardíaca são siderófagos de alvéolos de pacientes com insuficiência cardíaca esquerda ou edema pulmonar crônico, quando a hipertensão pulmonar faz com que os glóbulos vermelhos passem pela parede vascular. Os siderófagos não são específicos da insuficiência cardíaca. Eles estão presentes em processos nos quais glóbulos vermelhos encontram macrófagos, como na hemorragia pulmonar . (pt) Als Siderophagen werden Makrophagen bezeichnet, die Hämosiderin, ein Abbauprodukt des Blutfarbstoffes Hämoglobin, phagozytiert haben. Dem histologischen oder zytologischen Nachweis von Siderophagen kommt in der Pathologie diagnostische Bedeutung als Hinweis auf ältere Einblutungen zu. Nach einer Subarachnoidalblutung können sie beispielsweise im Liquor cerebrospinalis nachgewiesen werden. In den Lungenalveolen finden sich Siderophagen als sogenannte „Herzfehlerzellen“ bei chronischer Lungenstauung, z. B. im Rahmen einer chronischen Linksherzinsuffizienz. (de) A siderophage is a hemosiderin-containing macrophage. Heart failure cells are siderophages generated in the alveoli of the lungs of people with left heart failure or chronic pulmonary edema, when the high pulmonary blood pressure causes red blood cells to pass through the vascular wall. Siderophages are not specific of heart failure. They are present wherever red blood cells encounter macrophages, such as pulmonary hemorrhage. (en) |
| rdfs:label | Siderophage (de) 心臓病細胞 (ja) Siderophage (en) Siderófago (pt) |
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| prov:wasDerivedFrom | wikipedia-en:Siderophage?oldid=1071228343&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Siderophages_in_endometriotic_focus.jpg wiki-commons:Special:FilePath/Histopathology_of_sid...e_in_chronic_pulmonary_congestion.jpg |
| foaf:isPrimaryTopicOf | wikipedia-en:Siderophage |
| is dbo:wikiPageRedirects of | dbr:Heart_failure_cells dbr:Heart_failure_cell dbr:Hemosiderin-laden_macrophage |
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| is dbp:caption of | dbr:Macrophage |
| is foaf:primaryTopic of | wikipedia-en:Siderophage |
