| dbo:abstract |
Sivelestat (nombre DCI ONO 5046, comercializado como Elaspol) es un inhibidor de la proteína humana y está siendo probada en el tratamiento de afecciones pulmonares como insuficiencia respiratoria y fibrosis pulmonar. (es) Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase. It is used in the treatment of acute respiratory failure and preliminary studies show it may also improve neuropathic pain. (en) シベレスタット（Sivelestat）は、ヒト好中球エラスターゼの選択的阻害薬である。急性呼吸不全の治療に用いられる。商品名エラスポール。開発コードONO 5046。 (ja) |
| dbo:casNumber |
127373-66-4 |
| dbo:chEMBL |
76688 |
| dbo:fdaUniiCode |
DWI62G0P59 |
| dbo:kegg |
D03788 |
| dbo:pubchem |
107706 |
| dbo:thumbnail |
wiki-commons:Special:FilePath/Sivelestat.svg?width=300 |
| dbo:wikiPageID |
18681307 (xsd:integer) |
| dbo:wikiPageLength |
3622 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID |
1033010982 (xsd:integer) |
| dbo:wikiPageWikiLink |
dbr:Intravenous_therapy dbc:Hydrolase_inhibitors dbc:Pivalate_esters dbr:Neutrophil_elastase dbc:Benzamides dbr:Respiratory_failure dbr:International_Nonproprietary_Name dbc:Sulfonamides dbr:File:Sivelestat_scheme.png |
| dbp:atcPrefix |
None (en) |
| dbp:c |
20 (xsd:integer) |
| dbp:casNumber |
127373 (xsd:integer) |
| dbp:chembl |
76688 (xsd:integer) |
| dbp:chemspiderid |
96875 (xsd:integer) |
| dbp:h |
22 (xsd:integer) |
| dbp:iupacName |
N-{2-[amino]benzoyl}glycine (en) |
| dbp:iupharLigand |
6441 (xsd:integer) |
| dbp:kegg |
D03788 (en) |
| dbp:legalStatus |
Rx-only (en) |
| dbp:legalUs |
Not approved (en) |
| dbp:n |
2 (xsd:integer) |
| dbp:o |
7 (xsd:integer) |
| dbp:pubchem |
107706 (xsd:integer) |
| dbp:routesOfAdministration |
dbr:Intravenous_therapy |
| dbp:s |
1 (xsd:integer) |
| dbp:smiles |
CCCOC1=CC=CSNC2=CC=CC=C2CNCCO (en) |
| dbp:stdinchi |
1 (xsd:integer) |
| dbp:stdinchikey |
BTGNGJJLZOIYID-UHFFFAOYSA-N (en) |
| dbp:unii |
DWI62G0P59 (en) |
| dbp:verifiedfields |
changed (en) |
| dbp:verifiedrevid |
464392270 (xsd:integer) |
| dbp:watchedfields |
changed (en) |
| dbp:wikiPageUsesTemplate |
dbt:Respiratory-system-drug-stub dbt:Drugbox dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Drugs.com |
| dcterms:subject |
dbc:Hydrolase_inhibitors dbc:Pivalate_esters dbc:Benzamides dbc:Sulfonamides |
| gold:hypernym |
dbr:Inhibitor |
| rdf:type |
owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Inhibitor114724436 yago:Matter100020827 yago:PhysicalEntity100001930 yago:WikicatHydrolaseInhibitors dbo:Drug yago:Substance100020090 |
| rdfs:comment |
Sivelestat (nombre DCI ONO 5046, comercializado como Elaspol) es un inhibidor de la proteína humana y está siendo probada en el tratamiento de afecciones pulmonares como insuficiencia respiratoria y fibrosis pulmonar. (es) Sivelestat (INN, research name ONO 5046, marketed as Elaspol) is an inhibitor of human neutrophil elastase. It is used in the treatment of acute respiratory failure and preliminary studies show it may also improve neuropathic pain. (en) シベレスタット（Sivelestat）は、ヒト好中球エラスターゼの選択的阻害薬である。急性呼吸不全の治療に用いられる。商品名エラスポール。開発コードONO 5046。 (ja) |
| rdfs:label |
Sivelestat (es) シベレスタット (ja) Sivelestat (en) |
| owl:sameAs |
freebase:Sivelestat yago-res:Sivelestat wikidata:Sivelestat dbpedia-es:Sivelestat dbpedia-ja:Sivelestat dbpedia-sh:Sivelestat dbpedia-sr:Sivelestat https://global.dbpedia.org/id/4kdJT |
| prov:wasDerivedFrom |
wikipedia-en:Sivelestat?oldid=1033010982&ns=0 |
| foaf:depiction |
wiki-commons:Special:FilePath/Sivelestat.svg wiki-commons:Special:FilePath/Sivelestat_scheme.png |
| foaf:isPrimaryTopicOf |
wikipedia-en:Sivelestat |
| is dbo:wikiPageRedirects of |
dbr:Elaspol dbr:Sivelestat_sodium |
| is dbo:wikiPageWikiLink of |
dbr:Endopeptidase_inhibitor dbr:Elaspol dbr:Neuromyelitis_optica_spectrum_disorder dbr:List_of_drugs:_Si dbr:Sivelestat_sodium |
| is foaf:primaryTopic of |
wikipedia-en:Sivelestat |
