Small Maf (original) (raw)
Small Maf (musculoaponeurotic fibrosarcoma) proteins are basic region leucine zipper-type transcription factors that can bind to DNA and regulate gene regulation. There are three small Maf (sMaf) proteins, namely MafF, MafG, and MafK, in vertebrates. HUGO Gene Nomenclature Committee (HGNC)-approved gene names of MAFF, MAFG and MAFK are “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F, G, and K”, respectively.
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| dbo:abstract | Small Maf (musculoaponeurotic fibrosarcoma) proteins are basic region leucine zipper-type transcription factors that can bind to DNA and regulate gene regulation. There are three small Maf (sMaf) proteins, namely MafF, MafG, and MafK, in vertebrates. HUGO Gene Nomenclature Committee (HGNC)-approved gene names of MAFF, MAFG and MAFK are “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F, G, and K”, respectively. Through the leucine zipper structures, sMafs form homodimers by themselves and heterodimers with other specific bZIP transcription factors, such as transcription factors of the CNC (cap 'n' collar) and Bach families. Because CNC and Bach proteins cannot bind to DNA by themselves, sMafs are indispensable partners of the CNC and Bach families of transcription factors. Through interactions with these transcription factors, sMafs actively participate in transcriptional activation or repression depending on the nature of the heterodimeric partners. (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/W-F1.jpg?width=300 |
| dbo:wikiPageID | 49789079 (xsd:integer) |
| dbo:wikiPageLength | 25773 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1045335827 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:MAFG dbr:MAFK dbr:SUMOylation dbr:Homozygotes dbc:Proteins dbr:GATA1 dbr:GATA2 dbr:GATA4 dbr:GATA6 dbr:GATA_transcription_factor dbr:Heterozygote dbr:BACH1 dbr:BACH2 dbr:MAFF_(gene) dbr:MAF_(gene) dbr:NFE2 dbr:NFE2L1 dbr:NFE2L2 dbr:NFE2L3 dbr:File:W-F1.jpg dbr:File:W-F2.jpg dbr:File:W-F3.jpg |
| dbp:wikiPageUsesTemplate | dbt:Gene dbt:Reflist dbt:Short_description |
| dct:subject | dbc:Proteins |
| rdfs:comment | Small Maf (musculoaponeurotic fibrosarcoma) proteins are basic region leucine zipper-type transcription factors that can bind to DNA and regulate gene regulation. There are three small Maf (sMaf) proteins, namely MafF, MafG, and MafK, in vertebrates. HUGO Gene Nomenclature Committee (HGNC)-approved gene names of MAFF, MAFG and MAFK are “v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F, G, and K”, respectively. (en) |
| rdfs:label | Small Maf (en) |
| owl:sameAs | yago-res:Small Maf wikidata:Small Maf https://global.dbpedia.org/id/2PF7F |
| prov:wasDerivedFrom | wikipedia-en:Small_Maf?oldid=1045335827&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/W-F1.jpg wiki-commons:Special:FilePath/W-F2.jpg wiki-commons:Special:FilePath/W-F3.jpg |
| foaf:isPrimaryTopicOf | wikipedia-en:Small_Maf |
| is dbo:wikiPageWikiLink of | dbr:MAFG dbr:MAFK dbr:BACH1 dbr:MAFF_(gene) dbr:NFE2L1 dbr:NFE2L2 |
| is rdfs:seeAlso of | dbr:MAFG dbr:MAFK |
| is foaf:primaryTopic of | wikipedia-en:Small_Maf |
