Strictosidine (original) (raw)
La Estrictosidina es un alcaloide β-carbolínico, que es intermediario en la biosíntesis de diversos alcaloides.
| Property | Value |
|---|---|
| dbo:abstract | La Estrictosidina es un alcaloide β-carbolínico, que es intermediario en la biosíntesis de diversos alcaloides. (es) Strictosidin ist ein Vincaalkaloid aus und dem Madagaskar-Immergrün (Catharanthus roseus) aus der Familie der Hundsgiftgewächse. In der Synthese der Indolalkaloide spielt Strictosidin eine wichtige Rolle: Es ist der vermutete Vorläufer von über 1400 unterschiedlichen Indol-Terpen-Alkaloiden. Zu erwähnen ist das Opioid Mitragynin, dessen Vorläufer Strictosidin ist, und somit für die Erforschung der Biosynthese von Opioiden neuer Generation eine große Rolle spielt. (de) La strictosidine est un alcaloïde indole-terpénique, de formule C27H34N2O9. C'est un métabolite végétal notamment présent chez Catharanthus roseus, et . (fr) Strictosidine is a natural chemical compound and is classified as a and a vinca alkaloid. It is formed by the Pictet–Spengler condensation reaction of tryptamine with secologanin, catalyzed by the enzyme strictosidine synthase. Thousands of strictosidine derivatives are sometimes referred to by the broad phrase of monoterpene indole alkaloids. Strictosidine is an intermediate in the biosynthesis of numerous pharmaceutically valuable metabolites including quinine, camptothecin, ajmalicine, serpentine, vinblastine, vincristine and mitragynine. Biosynthetic pathways help to define the subgroups of strictosidine derivatives. (en) |
| dbo:alternativeName | Isovincoside (en) |
| dbo:iupacName | Methyl (4S,5R,6S)-5-ethenyl-4-{[(1S)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl}-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5,6-dihydro-4H-pyran-3-carboxylate (en) Methyl 20β-ethenyl-19α-(β-(D)-glucopyranosyloxy)-18-oxa-21-noryohimb-16-ene-16-carboxylate (en) |
| dbo:thumbnail | wiki-commons:Special:FilePath/Strictosidine_skeletal.svg?width=300 |
| dbo:wikiPageID | 45382989 (xsd:integer) |
| dbo:wikiPageLength | 3853 (xsd:nonNegativeInteger) |
| dbo:wikiPageRevisionID | 1068348467 (xsd:integer) |
| dbo:wikiPageWikiLink | dbr:Camptothecin dbr:Quinine dbr:Rubiaceae dbr:Monoterpene dbr:Apocynaceae dbr:Vinblastine dbr:Vincristine dbr:Derivative_(chemistry) dbr:Saccharomyces_cerevisiae dbr:Nyssaceae dbc:Indole_alkaloids dbc:Vinyl_compounds dbr:Chemical_compound dbr:Condensation_reaction dbr:Loganiaceae dbc:Glucosides dbr:Tryptamine dbr:Ajmalicine dbr:Alangiaceae dbr:Biosynthesis dbr:Pictet–Spengler_reaction dbr:Icacinaceae dbr:Secologanin dbr:Serpentine_(Alkaloid) dbr:Strictosidine_synthase dbr:Indole_alkaloids |
| dbp:imagealt | Structure of strictosidine (en) |
| dbp:imagefile | Strictosidine skeletal.svg (en) |
| dbp:iupacname | Methyl 20β-ethenyl-19α--18-oxa-21-noryohimb-16-ene-16-carboxylate (en) |
| dbp:othernames | Isovincoside (en) |
| dbp:pin | Methyl -5-ethenyl-4-{[-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl]methyl}-6-{[-3,4,5-trihydroxy-6-oxan-2-yl]oxy}-5,6-dihydro-4H-pyran-3-carboxylate (en) |
| dbp:wikiPageUsesTemplate | dbt:Chembox dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist |
| dcterms:subject | dbc:Indole_alkaloids dbc:Vinyl_compounds dbc:Glucosides |
| gold:hypernym | dbr:Alkaloid |
| rdf:type | owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound |
| rdfs:comment | La Estrictosidina es un alcaloide β-carbolínico, que es intermediario en la biosíntesis de diversos alcaloides. (es) Strictosidin ist ein Vincaalkaloid aus und dem Madagaskar-Immergrün (Catharanthus roseus) aus der Familie der Hundsgiftgewächse. In der Synthese der Indolalkaloide spielt Strictosidin eine wichtige Rolle: Es ist der vermutete Vorläufer von über 1400 unterschiedlichen Indol-Terpen-Alkaloiden. Zu erwähnen ist das Opioid Mitragynin, dessen Vorläufer Strictosidin ist, und somit für die Erforschung der Biosynthese von Opioiden neuer Generation eine große Rolle spielt. (de) La strictosidine est un alcaloïde indole-terpénique, de formule C27H34N2O9. C'est un métabolite végétal notamment présent chez Catharanthus roseus, et . (fr) Strictosidine is a natural chemical compound and is classified as a and a vinca alkaloid. It is formed by the Pictet–Spengler condensation reaction of tryptamine with secologanin, catalyzed by the enzyme strictosidine synthase. Thousands of strictosidine derivatives are sometimes referred to by the broad phrase of monoterpene indole alkaloids. Strictosidine is an intermediate in the biosynthesis of numerous pharmaceutically valuable metabolites including quinine, camptothecin, ajmalicine, serpentine, vinblastine, vincristine and mitragynine. (en) |
| rdfs:label | Strictosidin (de) Estrictosidina (es) Strictosidine (fr) Strictosidine (en) |
| owl:sameAs | freebase:Strictosidine yago-res:Strictosidine wikidata:Strictosidine dbpedia-de:Strictosidine dbpedia-es:Strictosidine dbpedia-fi:Strictosidine dbpedia-fr:Strictosidine https://global.dbpedia.org/id/2EASe |
| prov:wasDerivedFrom | wikipedia-en:Strictosidine?oldid=1068348467&ns=0 |
| foaf:depiction | wiki-commons:Special:FilePath/Strictosidine_skeletal.svg |
| foaf:isPrimaryTopicOf | wikipedia-en:Strictosidine |
| is dbo:wikiPageRedirects of | dbr:C27H34N2O9 dbr:Isovincoside |
| is dbo:wikiPageWikiLink of | dbr:Camptothecin dbr:Quinine dbr:Alkaloid dbr:Vinervine dbr:Vobasine dbr:Indole_alkaloid dbr:Conophylline dbr:Gelsemine dbr:Stemmadenine dbr:Strychnine dbr:C27H34N2O9 dbr:Catharanthine dbr:Iridoid dbr:Akuammicine dbr:Dregamine dbr:Tabernaemontanine dbr:Triosteum dbr:Palicourea_elata dbr:Strictosidine_beta-glucosidase dbr:Strictosidine_synthase dbr:Isovincoside |
| is foaf:primaryTopic of | wikipedia-en:Strictosidine |
