Stuart A. Aaronson (original) (raw)
- Stuart A. Aaronson (* 28. Februar 1942 in Mount Clemens, Michigan) ist ein US-amerikanischer Krebsforscher. Aaronson machte 1962 seinen Bachelor-Abschluss in Chemie an der University of California in Berkeley und wurde 1966 in Medizin an der Medical School der University of California in San Francisco promoviert (M.D. Abschluss). Danach war er mit einem Stipendium an der University of Cambridge und machte seine Facharztausbildung (Internship) am Moffitt Hospital in San Francisco. Ab 1967 war er im Bereich Krebsviren (Viral Cancerogenesis) an den National Institutes of Health, ab 1969 als Senior Staff Fellow und von 1970 bis 1977 als Leiter der Abteilung Molekularbiologie im Bereich Krebsvirusforschung. Danach war er Leiter des Labors für Zell- und Molekularbiologie des National Cancer Institute. 1993 wurde er Vorstand (Chairman) der Onkologie (Oncological Sciences) am Mount Sinai Medical Center (Direktor des Derald H. Ruttenberg Cancer Center) und ist dort Jane B. and Jack R. Aron Professor of Neoplastic Diseases. 1984 bis 1987 war er wissenschaftlicher Berater der American Cancer Society. 1981 wurde er Mitherausgeber von Cancer Research. Er ist Verfasser von über 530 wissenschaftlichen Aufsätzen (2010) und hält über 50 Patente. Aaronson gelangen wichtige Entdeckungen über Onkogene, teilweise mit Hilfe einer von ihm entwickelten cDNA-Klonierungstechnik (stable expression cDNA cloning). So entdeckte er mit Kollegen die erste normale Funktionsweise eines Onkogens bei v-sis als Wachstumsfaktor in der Zellkommunikation. Er entdeckte erbB2 als verstärkt in Brustkrebs aktivem Gen und entdeckte den für Epithelzellen spezifischen Wachstumsfaktor KGF (Keratinocyte Growth Factor, FGF7) und seine Rolle in der Wundheilung, was zur Entwicklung des Medikaments Kepivance (durch Amgen) zum Beispiel gegen orale Mukositis führte. Mit Kollegen entdeckte er, dass das in Protoonkogenen kodierte MET ein Rezeptor für HGF/SF (Heptatocyte Growth Factor/Scatter Factor) ist. (de)
- Stuart A. Aaronson, M.D. (born February 28, 1942) is an American author and internationally recognized cancer biologist. He has authored more than 500 publications and holds over 50 patents, and was the Jane B. and Jack R. Aron Professor of Neoplastic Diseases and Chairman of Oncological Sciences at The Mount Sinai Hospital in New York City until March 2013, when he assumed the title of Founding Chair Emeritus of the Department of Oncological Sciences. The current Chairman of Oncological Sciences is Ramon E. Parsons. (en)
- Stuart A. Aaronson (Mount Clemens, 28 de fevereiro de 1942) é um pesquisador do câncer estadunidense. Aaronson obteve um bacharelado em química em 1962 na Universidade da Califórnia em Berkeley, obtendo um doutorado em medicina em 1966 na Escola de Medicina da Universidade da Califórnia em São Francisco (título de M.D.). Obteve depois uma bolsa de estudos para a Universidade de Cambridge e realizou uma parte de sua residência médica no Moffitt Hospital em São Francisco (Califórnia). A partir de 1967 trabalhou na área de cancerogênese viral nos Institutos Nacionais da Saúde, a partir de 1969 como Senior Staff Fellow e de 1970 a 1977 diretor do Departamento de Biologia Molecular na especialidade pesquisa do câncer. Foi depois diretor do Laboratório de Biologia Celular e Molecular do National Cancer Institute. Em 1993 foi diretor de oncologia do Hospital Mount Sinai. Recebeu em 1989 o Prêmio Paul Ehrlich e Ludwig Darmstaedter. (pt)
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- https://www.nytimes.com/1983/09/28/us/activation-of-a-cancer-gene-by-single-mutation-reported.html
- https://www.nytimes.com/1984/02/10/us/cancer-gene-linked-to-flaws-in-growth-of-an-ordinary-cell.html
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- Stuart A. Aaronson, M.D. (born February 28, 1942) is an American author and internationally recognized cancer biologist. He has authored more than 500 publications and holds over 50 patents, and was the Jane B. and Jack R. Aron Professor of Neoplastic Diseases and Chairman of Oncological Sciences at The Mount Sinai Hospital in New York City until March 2013, when he assumed the title of Founding Chair Emeritus of the Department of Oncological Sciences. The current Chairman of Oncological Sciences is Ramon E. Parsons. (en)
- Stuart A. Aaronson (* 28. Februar 1942 in Mount Clemens, Michigan) ist ein US-amerikanischer Krebsforscher. Aaronson machte 1962 seinen Bachelor-Abschluss in Chemie an der University of California in Berkeley und wurde 1966 in Medizin an der Medical School der University of California in San Francisco promoviert (M.D. Abschluss). Danach war er mit einem Stipendium an der University of Cambridge und machte seine Facharztausbildung (Internship) am Moffitt Hospital in San Francisco. Ab 1967 war er im Bereich Krebsviren (Viral Cancerogenesis) an den National Institutes of Health, ab 1969 als Senior Staff Fellow und von 1970 bis 1977 als Leiter der Abteilung Molekularbiologie im Bereich Krebsvirusforschung. Danach war er Leiter des Labors für Zell- und Molekularbiologie des National Cancer Inst (de)
- Stuart A. Aaronson (Mount Clemens, 28 de fevereiro de 1942) é um pesquisador do câncer estadunidense. Aaronson obteve um bacharelado em química em 1962 na Universidade da Califórnia em Berkeley, obtendo um doutorado em medicina em 1966 na Escola de Medicina da Universidade da Califórnia em São Francisco (título de M.D.). Obteve depois uma bolsa de estudos para a Universidade de Cambridge e realizou uma parte de sua residência médica no Moffitt Hospital em São Francisco (Califórnia). A partir de 1967 trabalhou na área de cancerogênese viral nos Institutos Nacionais da Saúde, a partir de 1969 como Senior Staff Fellow e de 1970 a 1977 diretor do Departamento de Biologia Molecular na especialidade pesquisa do câncer. Foi depois diretor do Laboratório de Biologia Celular e Molecular do National (pt)
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