| dbo:abstract |
Sulfanegen is an experimental antidote for cyanide poisoning. It is being studied as a prodrug for 3-mercaptopyruvic acid (3-MP). 3-MP has been studied as a potential treatment for cyanide poisoning, but the half-life is too short for it to be clinically effective. Instead, alternative chemicals such as sulfanegen, the hemithioacetal cyclic dimer of 3-MP, are being evaluated that produce 3-MP in vivo to compensate for the short half-life of 3-MP itself. Sulfanegen has been shown to be effective in animal studies. It is being studied as the disodium salt, sulfanegen sodium, and the triethanolamine salt, sulfanegen TEA. One advantage various sulfanegen formulations have over existing treatments for acute cyanide poisoning is that they might be administered by intramuscular injection or orally rather than by intravenous infusion. (en) 2,5-二羟基-1,4-二硫杂环己烷-2,5-二甲酸（Sulfanegen）是一种有机硫化合物，化学式为C6H8O6S2，它是氰化物中毒的实验性解毒剂。它的二钠盐和三乙醇胺盐也在研究。这些盐可以直接通过酸碱中和反应来制备。 (zh) |
| dbo:iupacName |
2,5-Dihydroxy-1,4-dithiane-2,5-dicarboxylic acid (en) |
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| gold:hypernym |
dbr:Antidote |
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| rdfs:comment |
2,5-二羟基-1,4-二硫杂环己烷-2,5-二甲酸（Sulfanegen）是一种有机硫化合物，化学式为C6H8O6S2，它是氰化物中毒的实验性解毒剂。它的二钠盐和三乙醇胺盐也在研究。这些盐可以直接通过酸碱中和反应来制备。 (zh) Sulfanegen is an experimental antidote for cyanide poisoning. It is being studied as a prodrug for 3-mercaptopyruvic acid (3-MP). 3-MP has been studied as a potential treatment for cyanide poisoning, but the half-life is too short for it to be clinically effective. Instead, alternative chemicals such as sulfanegen, the hemithioacetal cyclic dimer of 3-MP, are being evaluated that produce 3-MP in vivo to compensate for the short half-life of 3-MP itself. (en) |
| rdfs:label |
Sulfanegen (en) 2,5-二羟基-1,4-二硫杂环己烷-2,5-二甲酸 (zh) |
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freebase:Sulfanegen yago-res:Sulfanegen wikidata:Sulfanegen dbpedia-zh:Sulfanegen https://global.dbpedia.org/id/X2ZE |
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